Bio

Posizione attuale

 

  • Professore Ordinario di Statistica Medica ed Epidemiologia presso Unisr
  • Dal 2007 Professore incaricato di Statistica presso l’Università degli Studi della Svizzera Italiana sede Lugano
  • Dal 2005 Direttore del CUSSB (University Centre for Statistics in the Biomedical Sciences)cussb.unisr.it

.

 

 

Breve Curriculum

 

  • 2015 Presidente della Società Italiana Di Biometria (International Biometrics Socienty, Italian Region) con decorrenza 2016-2020.
  • 2005-2015 Professore Associato in Statistica presso Unisr
  • 2001 – 2004 Technical University in Munich (Germany) responsabile dell’unità di Statistica dell MSIF (Multiple Sclerosis International Foundation), Sylvia Lawry Centre.
  • 1996 – 2000 periodo post-doc presso la Duke University, UCLA, e Johns Hopkins University. (semestri estivi)
  • 1996-2000 Docente di Statistica presso Unisr
  • 1992-1996. Dottorato in Statistica ( Chapel Hill, PhD program University of North Carolina-USA joint with University of Trento)
  • 1995-1996 Tesi di Dottorato presso il Dipartimento di Biostatistica dell’Università di Copenhagen (Denmark)
  • 1991: Laurea in Economia con indirizzo statistico.

 

Principali collaborazioni scientifiche:

 

INTERNAZIONALI

  • SFI (Statistics for Innovation Department) (Oslo, Norwey). Prof. Frigessi
  • Institute of Statistics and Probability (Groeningen, Holland)
  • Inter Disciplinary Institute of Data Science (USI-Switzerland)
  • Institute of Bioinformatics and Statistics, Department of Molecular Biology, (Netherlands)
  • Cancer Institute, Amsterdam.
  • Walter and Hiliza Hall, Medical Centre, Melbourne- Australia
  • Department of Decision Sciences, Tel Aviv, (Israel).
  • MRC Cambridge,(UK)

NAZIONALI

  • Istituto di Statistica Medica e Biometria Università degli Studi di Milano
  • Università Bocconi di Milano
  • Politecnico di Milano (facoltà di bioingegneria)
  • Università RomaTre

 

Interessi di ricerca principali.

  • Modelli grafici e reti bayesiane per lo studio delle malattie complesse
  • Modelli statistici per lo studio dell’evoluzione di malattia negli studi longitudinali (applicazioni in malattie complesse, virologia, oncologia.)
  • Modelli statistici per la genetica e genomica.
  • Studio della struttura di dipendenza sottostante alla System Biology.
  • Modelli di sopravvivenza multivariata a rischi competitivi
  • Studio di paradossi probabilistici in biomedicina
  • Valutazione dei fattori prognostici
  • Modelli predittivi per il corso di malattia
  • Studio di biomarcatori biologici e clinici

Pubblicazioni (una selezione)

2016

Pellin D., Di Serio M (2016). A novel scan statistics approach for clustering identification and comparison in binary genomic data. BMC BIOINFORMATICS, ISSN: 1471-2105, doi: DOI: 10.1186/s12859-016-1173-8
A. Esposito, A. Palmisano, S. Antunes, G. Maccabelli, C. Colantoni, P.M.V. Rancoita, F. Baratto, Di Serio M, G. Rizzo, F. De Cobelli, P. Della Bella, A. Del Maschio (2016). Cardiac CT With Delayed Enhancement in the Characterization of Ventricular Tachycardia Structural Substrate : Relationship Between CT-Segmented Scar an

Brombin C, Di Serio M (2016). Evaluating treatment e effect within a multivariate stochastic ordering framework: NPC methodology applied to a study on Multiple Sclerosis. STATISTICAL METHODS IN MEDICAL RESEARCH, vol. 25, p. 366-384, ISSN: 0962-2802, doi: 10.1177/096228021245420

L. Barcellini, E. Borroni, J. Brown, E. Brunetti, D. Campisi, P.F. Castellotti, L. Codecasa, F. Cugnata, Di Serio M, M. Ferraresi, D. Goletti, M. Lipman, P.M.V. Rancoita, G. Russo, M. Tadolini, E. Vanino and D.M. Cirillo (2016). First evaluation of QuantiFERON-TB Gold Plus performance in contact screening. EUROPEAN RESPIRATORY JOURNAL, ISSN: 0903-1936
L. Barcellini, E. Borroni, J. Brown, E. Brunetti, L. Codecasa, F. Cugnata, P. Dal Monte, Di Serio M, D. Goletti, G. Lombardi, M. Lipman, P.M.V. Rancoita, M. Tadolini and D.M. Cirillo (2016). First independent evaluation of QuantiFERON-TB Plus performance. EUROPEAN RESPIRATORY JOURNAL, vol. 47, p. 1587-1590, ISSN: 0903-1936

Biasco, D. Pellin, S. Scala, F. Dionisio, L. Basso-Ricci, L. Leonardelli, S. Scaramuzza, C. Baricordi, F. Ferrua, M.P. Cicalese, S. Giannelli, V. Neduva, D.J. Dow, M. Schmidt, C. Von Kalle, M.G. Roncarolo, F. Ciceri, P. Vicard, E. Wit, Di Serio M, L. Naldini, A. Aiuti (2016). In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases. CELL STEM CELL, vol. 19, p. 107-119, ISSN: 1934-5909

G. Farinelli, R.J. Hernandez, A. Rossi, S. Ranucci, F. Sanvito, M. Migliavacca, C. Brombin, A. Pramov, Di Serio M, C. Bovolenta, B. Gentner, A. Bragonzi and A. Aiuti (2016). Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response. MOLECULAR THERAPY, ISSN: 1525-0016
M. Sessa, L. Lorioli, F. Fumagalli, S. Acquati, D. Redaelli, C. Baldoli, S. Canale, I.D. Lopez, F. Morena, A. Calabria, R. Fiori, P. Silvani, P.M.V. Rancoita, M. Gabaldo, F. Benedicenti, G. Antonioli, A. Assanelli, M.P. Cicalese, U. del Carro, M.G. Natali Sora, S. Martino, A. Quattrini, E. Montini, Di Serio M, F. Ciceri, M.G. Roncarolo, A. Aiuti, L. Naldini, A. Biffi (2016). Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial. THE LANCET, vol. 388, p. 476-487, ISSN: 0099-5355

P.M.V. Rancoita, M. Valberg, R. Demicheli, E. Biganzoli, Di Serio M (2016). Tumor dormancy and frailty models: A novel approach. BIOMETRICS, ISSN: 0006-341X

2015

  1. P Rancoita, M Valberg, R Dermicheli, E Biganzoli and C Di Serio, “Tumor dormancy and frailty models: a novel approach”, under second revision Biometrics, 2015.

 

  1. Filippo Trentini, Matteo Malgaroli, Anne Linda Camerini, Clelia Di Serio, Peter Schulz, “Multivariate determinants of self-management in Health Care: assessing Health Empowerment Model by comparison between structural equation and graphical models approaches” Epidemiology Biostatistics and Publich Health Vol 12, Issue 1 2015

 

  1. Mickael Lelek, Nicoletta Casartelli, Danilo Pellin, Ermanno Rizzi, Marco Severgnini, Clelia Di Serio, Thomas Fricke, Felipe Diaz-Griffero, Christophe Zimmer, Pierre Charneau, and Francesca Di Nunzio”Chromatin organization at the nuclear pore favours HIV replication”  , Nature Communications, Vol 6, February 2015
  2. Rossella Baldan, Paola Maria Vittoria Rancoita, Clelia Di Serio, and Daniela Maria Cirillo, “Epidemic MRSA clone ST22-IV is more resistant to multiple host- and environment-related stresses compared with ST228-I”, Journal of antibicrobic chemotherapy, Vol 70, issue 3, 2015

2014

  1. Baldan R, Cigana C, Testa F, Bianconi I, De Simone M, Pellin D, Di Serio M, Bragonzi A, Cirillo DM. (2014). Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infection. PLOS ONE, vol. 9, ISSN: 1932-6203, doi: 10.1371
  2. Danilo Pellin, Clelia Di Serio (February 2014), “Clusters Identification in Binary Genomic Data: The Alternative Offered by Scan Statistics Approach”, Lecture Notes in Computer Science Volume 8452, pp 149-158
  3. Brombin, C., Di Serio M, Rancoita, P. M. V (2014). Joint modeling of HIV data in multicentre observational studies: a comparison among different approaches. STATISTICAL METHODS IN MEDICAL RESEARCH, vol. 23, ISSN: 0962-2802, doi: 10.1177/0962280214526192
  4. Pietro Ciampi, Celeste Scotti, Alessandro Nonis, Matteo Vitali, Di Serio M, Giuseppe M Peretti, Gianfranco Fraschini (2014). The Benefit of Synthetic Versus Biological Patch Augmentation in the Repair of Posterosuperior Massive Rotator Cuff Tears: A 3-Year Follow-up Study. THE AMERICAN JOURNAL OF SPORTS MEDICINE, vol. 42, p. 1169-1175, ISSN: 0363-5465
  5. Daniela Cesana, Marco Ranzani, Monica Volpin, Cynthia Bartholomae, Caroline Duros, Alexandre Artus, Stefania Merella, Fabrizio Benedicenti, Lucia Sergi Sergi, Francesca Sanvito, Chiara Brombin, Alessandro Nonis, Di Serio M, Claudio Doglioni, Christof von Kalle, Manfred Schmidt, Odile Cohen-Haguenauer, Luigi Naldini, Eugenio Montini (2014). Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo. MOLECULAR THERAPY, vol. 22, ISSN: 1525-0016

2013

  1. Brombin, C., Diomede, L., Tudor, D., Drillet, A. S., Pastori, C., Poli, E., Ri- va, A., Uberti-Foppa, C., Galli, M., Di Serio, C., Bomsel, M. and Lopalco, L. (2013). A nonparametric procedure for defining a new humoral immunological profile in a pilot study on HIV infected patients. PLoS One 8:e58768. DOI: 10.1371/journal.pone.0058768.
  2. Alessandra Biffi,Eugenio Montini,Laura Lorioli,Martina Cesani,Francesca Fumagalli,Tiziana Plati,Cristina Baldoli,Sabata Martino,Andrea Calabria,Sabrina Canale,Fabrizio Benedicenti,Giuliana Vallanti,Luca Biasco,Simone Leo,Nabil Kabbara,Gianluigi Zanetti,William B. Rizzo,Nalini A. L. Mehta,Maria Pia Cicalese,Miriam Casiraghi,Jaap J. Boelens,Ubaldo Del Carro,David J. Dow,Manfred Schmidt,Andrea Assanelli,Victor Neduva,Clelia Di Serio,Elia Stupka,Jason Gardner,Christof von Kalle,Claudio Bordignon,Fabio Ciceri,Attilio Rovelli,Maria Grazia Roncarolo,Alessandro Aiuti,Maria Sessa,and Luigi Naldini, “Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy”. Science 23 August 2013: 1233158, Published online 11 July 2013
  3. Alessandro Aiuti,Luca Biasco,Samantha Scaramuzza,Francesca Ferrua,Maria Pia Cicalese,Cristina Baricordi,Francesca Dionisio,Andrea Calabria,Stefania Giannelli,Maria Carmina Castiello,Marita Bosticardo,Costanza Evangelio,Andrea Assanelli,Miriam Casiraghi,Sara Di Nunzio,Luciano Callegaro,Claudia Benati,Paolo Rizzardi,Danilo Pellin,Clelia Di Serio,Manfred Schmidt,Christof Von Kalle,Jason Gardner,Nalini Mehta,Victor Neduva,David J. Dow,Anne Galy,Roberto Miniero,Andrea Finocchi,Ayse Metin,Pinaki P. Banerjee,Jordan S. Orange,Stefania Galimberti,Maria Grazia Valsecchi,Alessandra Biffi,Eugenio Montini,Anna Villa,Fabio Ciceri,Maria Grazia Roncarolo,and Luigi Naldini, “Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome”. Science 23 August 2013: 1233151Published online 11 July 2013
  4. Gagliani N., Magnani C.F., Huber S., Gianolini E., Pala M., Licona-Limon P., Guo B., De Broski H., Bulfone A., Trentini F., Di Serio C., Roncarolo M.G. et al (2013) “Co-expression of CD49b e LAG-3 identifies human and murine Tr1 cells”, Nature Medicine

2012

  • Danilo Pellin, Paolo Miotto, Alessandro Ambrosi, Daniela Maria Cirillo, and Clelia Di Serio, “A Genome-Wide Identification Analysis of Small Regulatory RNAs in Mycobacterium tuberculosis by RNA-Seq and Conservation Analysis”, (2012) PLoS ONE 7(3): e32723.doi:10.1371/journal.pone.0032723
  • Miotto P, Forti F, Ambrosi A, Pellin D, Veiga DF, Gabor Balazsi, Maria L. Gennaro, Clelia Di Serio, Daniela Ghisotti, Daniela M. Cirillo (2012), “Genome-Wide Discovery of Small RNAs in Mycobacterium tuberculosis”. PLoS ONE 7(12): e51950. doi:10.1371/journal.pone.0051950
  • Capotondo A, Milazzo R, Politi LS, Quattrini A, Palini A, Plati T, Merella S, Nonis A, Di Serio C, Montini E, Naldini L, Biffi A. “Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation”, PNAS 2012 Aug 23. doi: 10.1073/pnas.1205858109
  • Brombin, C., Di Serio, C. (2012) Evaluating treatment effect within a multivariate stochastic ordering framework: NPC methodology applied to a study on Multiple Sclerosis. Statistical Methods in Medical Research. DOI: 10.1177/0962280212454203. Article published online before print.
  • Brombin, C., Di Serio, C. and Crippa, M. (2012) Modeling cancer cells growth. Communications in Statistics-Theory and Methods. Special Issue-Statistics for complex problems, 41, 3043-3059.
  • Cantore, A., Nair, N., Della Valle, P., Di Matteo, M., Màtrai, J., Sanvito, F., Brombin, C., Di Serio, C., D’Angelo, A., Chuah, M., Naldini, L., VandenDries- sche, T. (2012) Hyper-functional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice. Blood. 120, 4517-20. DOI: 10.1182/blood- 2012-05-432591.
  • Xynos A, Neguembor MV, Caccia R, Licastro D, Nonis A, Di Serio C, Stupka E,Gabellini D. Overexpression of facioscapulohumeral muscular dystrophy region gene1 causes primary defects in myogenic stem cells. J Cell Sci. 2013 May 15;126(Pt10):2236-45. doi: 10.1242/jcs.121533. Epub 2013 Mar 22. PubMed PMID: 23525014

CURRENT POSITION:

Full Professor (permanent position) in medical statistics and epidemiology by Vita-Salute San Raffaele University.

Since 2007 Appointment as Professor in Statistics by State Swiss University (Lugano)

Since 2005 Director of University Centre for Statistics in the Biomedical Sciences (CUSSB) by international Science Park San Raffaele. www.cussb.unisr.it

 

Short CV

In 2015 elected President of International Biometrics Society, Italian region. (2016-2020)

2005-2015 Associate Professor in Statistics (Vita-Salute San Raffaele University)

2001 – 2004 Technical University in Munich (Germany) head of the core of Statistics for MSIF (Multiple Sclerosis International Foundation), Sylvia Lawry Centre.

1996 – 2000 post-doc by Duke University, UCLA, and Johns Hopkins University.

1996 Awarded with PhD in Statistics (Trento University)

1992-1996:PhD program in Statistics (jointly Trento University and University of North Carolina at Chapel Hill-North Carolina,USA).

1995-1996 junior statistician by Biostatistics Department in Copenhagen, PhD Thesis (Denmark)

1991: degree in economics and statistics.

 

MAIN INTERNATIONAL SCIENTIFIC COLLABORATION

INTERNATIONAL

  • SFI (Statistics for Innovation Department) (Oslo, Norwey). Frigessi
  • Institute of Statistics and Probability (Groeningen, Holland)
  • Inter Disciplinary Institute of Data Science (USI-Switzerland)
  • Institute of Bioinformatics and Statistics, Department of Molecular Biology, (Netherlands)
  • Cancer Institute, Amsterdam.
  • Walter and Hiliza Hall, Medical Centre, Melbourne- Australia
  • Department of Decision Sciences, Tel Aviv, (Israel).
  • MRC Cambridge,(UK)

NATIONAL

  • Istituto di Statistica Medica e Biometria Università degli Studi di Milano
  • Università Bocconi di Milano
  • Politecnico di Milano (facoltà di bioingegneria)
  • Università RomaTre

 

Main research interests.

  • Graphical modelling and Bayesian network analysis for complex disorders
  • Statistical modeling for longitudinal data (applications in oncology, virology,complex diseases)
  • Modelling unobserved dependence structures.Simpson paradox
  • Bioinformatics modelling (gene-expression microarray, aCGH, SNP microarray; Analysis of NGS data]
  • Competing risks dependence in survival analysis and oncology
  • Risk prediction models in oncology

 

RECENT PUBBLICATIONS

2015

  1. P Rancoita, M Valberg, R Dermicheli, E Biganzoli and C Di Serio, “Tumor dormancy and frailty models: a novel approach”, under second revision Biometrics, 2015.

 

  1. Filippo Trentini, Matteo Malgaroli, Anne Linda Camerini, Clelia Di Serio, Peter Schulz, “Multivariate determinants of self-management in Health Care: assessing Health Empowerment Model by comparison between structural equation and graphical models approaches” Epidemiology Biostatistics and Publich Health Vol 12, Issue 1 2015

 

  1. Mickael Lelek, Nicoletta Casartelli, Danilo Pellin, Ermanno Rizzi, Marco Severgnini, Clelia Di Serio, Thomas Fricke, Felipe Diaz-Griffero, Christophe Zimmer, Pierre Charneau, and Francesca Di Nunzio”Chromatin organization at the nuclear pore favours HIV replication”  , Nature Communications, Vol 6, February 2015
  2. Rossella Baldan, Paola Maria Vittoria Rancoita, Clelia Di Serio, and Daniela Maria Cirillo, “Epidemic MRSA clone ST22-IV is more resistant to multiple host- and environment-related stresses compared with ST228-I”, Journal of antibicrobic chemotherapy, Vol 70, issue 3, 2015

2016

Pellin D., Di Serio M (2016). A novel scan statistics approach for clustering identification and comparison in binary genomic data. BMC BIOINFORMATICS, ISSN: 1471-2105, doi: DOI: 10.1186/s12859-016-1173-8
A. Esposito, A. Palmisano, S. Antunes, G. Maccabelli, C. Colantoni, P.M.V. Rancoita, F. Baratto, Di Serio M, G. Rizzo, F. De Cobelli, P. Della Bella, A. Del Maschio (2016). Cardiac CT With Delayed Enhancement in the Characterization of Ventricular Tachycardia Structural Substrate : Relationship Between CT-Segmented Scar an

Brombin C, Di Serio M (2016). Evaluating treatment e effect within a multivariate stochastic ordering framework: NPC methodology applied to a study on Multiple Sclerosis. STATISTICAL METHODS IN MEDICAL RESEARCH, vol. 25, p. 366-384, ISSN: 0962-2802, doi: 10.1177/096228021245420

L. Barcellini, E. Borroni, J. Brown, E. Brunetti, D. Campisi, P.F. Castellotti, L. Codecasa, F. Cugnata, Di Serio M, M. Ferraresi, D. Goletti, M. Lipman, P.M.V. Rancoita, G. Russo, M. Tadolini, E. Vanino and D.M. Cirillo (2016). First evaluation of QuantiFERON-TB Gold Plus performance in contact screening. EUROPEAN RESPIRATORY JOURNAL, ISSN: 0903-1936
L. Barcellini, E. Borroni, J. Brown, E. Brunetti, L. Codecasa, F. Cugnata, P. Dal Monte, Di Serio M, D. Goletti, G. Lombardi, M. Lipman, P.M.V. Rancoita, M. Tadolini and D.M. Cirillo (2016). First independent evaluation of QuantiFERON-TB Plus performance. EUROPEAN RESPIRATORY JOURNAL, vol. 47, p. 1587-1590, ISSN: 0903-1936

Biasco, D. Pellin, S. Scala, F. Dionisio, L. Basso-Ricci, L. Leonardelli, S. Scaramuzza, C. Baricordi, F. Ferrua, M.P. Cicalese, S. Giannelli, V. Neduva, D.J. Dow, M. Schmidt, C. Von Kalle, M.G. Roncarolo, F. Ciceri, P. Vicard, E. Wit, Di Serio M, L. Naldini, A. Aiuti (2016). In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases. CELL STEM CELL, vol. 19, p. 107-119, ISSN: 1934-5909

G. Farinelli, R.J. Hernandez, A. Rossi, S. Ranucci, F. Sanvito, M. Migliavacca, C. Brombin, A. Pramov, Di Serio M, C. Bovolenta, B. Gentner, A. Bragonzi and A. Aiuti (2016). Lentiviral Vector Gene Therapy Protects XCGD Mice From Acute Staphylococcus aureus Pneumonia and Inflammatory Response. MOLECULAR THERAPY, ISSN: 1525-0016
M. Sessa, L. Lorioli, F. Fumagalli, S. Acquati, D. Redaelli, C. Baldoli, S. Canale, I.D. Lopez, F. Morena, A. Calabria, R. Fiori, P. Silvani, P.M.V. Rancoita, M. Gabaldo, F. Benedicenti, G. Antonioli, A. Assanelli, M.P. Cicalese, U. del Carro, M.G. Natali Sora, S. Martino, A. Quattrini, E. Montini, Di Serio M, F. Ciceri, M.G. Roncarolo, A. Aiuti, L. Naldini, A. Biffi (2016). Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial. THE LANCET, vol. 388, p. 476-487, ISSN: 0099-5355

P.M.V. Rancoita, M. Valberg, R. Demicheli, E. Biganzoli, Di Serio M (2016). Tumor dormancy and frailty models: A novel approach. BIOMETRICS, ISSN: 0006-341X

2014

  1. Baldan R, Cigana C, Testa F, Bianconi I, De Simone M, Pellin D, Di Serio M, Bragonzi A, Cirillo DM. (2014). Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infection. PLOS ONE, vol. 9, ISSN: 1932-6203, doi: 10.1371
  2. Danilo Pellin, Clelia Di Serio (February 2014), “Clusters Identification in Binary Genomic Data: The Alternative Offered by Scan Statistics Approach”, Lecture Notes in Computer Science Volume 8452, pp 149-158
  3. Brombin, C., Di Serio M, Rancoita, P. M. V (2014). Joint modeling of HIV data in multicentre observational studies: a comparison among different approaches. STATISTICAL METHODS IN MEDICAL RESEARCH, vol. 23, ISSN: 0962-2802, doi: 10.1177/0962280214526192
  4. Pietro Ciampi, Celeste Scotti, Alessandro Nonis, Matteo Vitali, Di Serio M, Giuseppe M Peretti, Gianfranco Fraschini (2014). The Benefit of Synthetic Versus Biological Patch Augmentation in the Repair of Posterosuperior Massive Rotator Cuff Tears: A 3-Year Follow-up Study. THE AMERICAN JOURNAL OF SPORTS MEDICINE, vol. 42, p. 1169-1175, ISSN: 0363-5465
  5. Daniela Cesana, Marco Ranzani, Monica Volpin, Cynthia Bartholomae, Caroline Duros, Alexandre Artus, Stefania Merella, Fabrizio Benedicenti, Lucia Sergi Sergi, Francesca Sanvito, Chiara Brombin, Alessandro Nonis, Di Serio M, Claudio Doglioni, Christof von Kalle, Manfred Schmidt, Odile Cohen-Haguenauer, Luigi Naldini, Eugenio Montini (2014). Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo. MOLECULAR THERAPY, vol. 22, ISSN: 1525-0016

2013

  1. Brombin, C., Diomede, L., Tudor, D., Drillet, A. S., Pastori, C., Poli, E., Ri- va, A., Uberti-Foppa, C., Galli, M., Di Serio, C., Bomsel, M. and Lopalco, L. (2013). A nonparametric procedure for defining a new humoral immunological profile in a pilot study on HIV infected patients. PLoS One 8:e58768. DOI: 10.1371/journal.pone.0058768.
  2. Alessandra Biffi,Eugenio Montini,Laura Lorioli,Martina Cesani,Francesca Fumagalli,Tiziana Plati,Cristina Baldoli,Sabata Martino,Andrea Calabria,Sabrina Canale,Fabrizio Benedicenti,Giuliana Vallanti,Luca Biasco,Simone Leo,Nabil Kabbara,Gianluigi Zanetti,William B. Rizzo,Nalini A. L. Mehta,Maria Pia Cicalese,Miriam Casiraghi,Jaap J. Boelens,Ubaldo Del Carro,David J. Dow,Manfred Schmidt,Andrea Assanelli,Victor Neduva,Clelia Di Serio,Elia Stupka,Jason Gardner,Christof von Kalle,Claudio Bordignon,Fabio Ciceri,Attilio Rovelli,Maria Grazia Roncarolo,Alessandro Aiuti,Maria Sessa,and Luigi Naldini, “Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy”. Science 23 August 2013: 1233158, Published online 11 July 2013
  3. Alessandro Aiuti,Luca Biasco,Samantha Scaramuzza,Francesca Ferrua,Maria Pia Cicalese,Cristina Baricordi,Francesca Dionisio,Andrea Calabria,Stefania Giannelli,Maria Carmina Castiello,Marita Bosticardo,Costanza Evangelio,Andrea Assanelli,Miriam Casiraghi,Sara Di Nunzio,Luciano Callegaro,Claudia Benati,Paolo Rizzardi,Danilo Pellin,Clelia Di Serio,Manfred Schmidt,Christof Von Kalle,Jason Gardner,Nalini Mehta,Victor Neduva,David J. Dow,Anne Galy,Roberto Miniero,Andrea Finocchi,Ayse Metin,Pinaki P. Banerjee,Jordan S. Orange,Stefania Galimberti,Maria Grazia Valsecchi,Alessandra Biffi,Eugenio Montini,Anna Villa,Fabio Ciceri,Maria Grazia Roncarolo,and Luigi Naldini, “Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome”. Science 23 August 2013: 1233151Published online 11 July 2013
  4. Gagliani N., Magnani C.F., Huber S., Gianolini E., Pala M., Licona-Limon P., Guo B., De Broski H., Bulfone A., Trentini F., Di Serio C., Roncarolo M.G. et al (2013) “Co-expression of CD49b e LAG-3 identifies human and murine Tr1 cells”, Nature Medicine

2012

  • Danilo Pellin, Paolo Miotto, Alessandro Ambrosi, Daniela Maria Cirillo, and Clelia Di Serio, “A Genome-Wide Identification Analysis of Small Regulatory RNAs in Mycobacterium tuberculosis by RNA-Seq and Conservation Analysis”, (2012) PLoS ONE 7(3): e32723.doi:10.1371/journal.pone.0032723
  • Miotto P, Forti F, Ambrosi A, Pellin D, Veiga DF, Gabor Balazsi, Maria L. Gennaro, Clelia Di Serio, Daniela Ghisotti, Daniela M. Cirillo (2012), “Genome-Wide Discovery of Small RNAs in Mycobacterium tuberculosis”. PLoS ONE 7(12): e51950. doi:10.1371/journal.pone.0051950
  • Capotondo A, Milazzo R, Politi LS, Quattrini A, Palini A, Plati T, Merella S, Nonis A, Di Serio C, Montini E, Naldini L, Biffi A. “Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation”, PNAS 2012 Aug 23. doi: 10.1073/pnas.1205858109
  • Brombin, C., Di Serio, C. (2012) Evaluating treatment effect within a multivariate stochastic ordering framework: NPC methodology applied to a study on Multiple Sclerosis. Statistical Methods in Medical Research. DOI: 10.1177/0962280212454203. Article published online before print.
  • Brombin, C., Di Serio, C. and Crippa, M. (2012) Modeling cancer cells growth. Communications in Statistics-Theory and Methods. Special Issue-Statistics for complex problems, 41, 3043-3059.
  • Cantore, A., Nair, N., Della Valle, P., Di Matteo, M., Màtrai, J., Sanvito, F., Brombin, C., Di Serio, C., D’Angelo, A., Chuah, M., Naldini, L., VandenDries- sche, T. (2012) Hyper-functional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice. Blood. 120, 4517-20. DOI: 10.1182/blood- 2012-05-432591.
  • Xynos A, Neguembor MV, Caccia R, Licastro D, Nonis A, Di Serio C, Stupka E,Gabellini D. Overexpression of facioscapulohumeral muscular dystrophy region gene1 causes primary defects in myogenic stem cells. J Cell Sci. 2013 May 15;126(Pt10):2236-45. doi: 10.1242/jcs.121533. Epub 2013 Mar 22. PubMed PMID: 23525014
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