Attività didattica a.a. 2016/2017

prevista ed erogata


PhD Student Invited Lectures

  • Venizelos Papayannopoulos, 05 dicembre 2016. Prof. Papayannopoulos will have an informal meeting/lunch with the PhD students
  • Alberto Mantovani, 14 dicembre 2016. “Inflammation and cancer: from bench to bedside”. After the seminar, Prof. Mantovani will have an informal meeting/lunch with the PhD students.
  • Fiona Powrie, 09 maggio 2017. Gut reactions: Immune pathways in the intestine in health and disease”

How not to bore the pants off your audience: efficient communication in English - 2017 edition

Prof. Michael John, from February 07th to April 04th 2017

Every biomedical professional understands the importance of the dictum Publish or perish. In today’s world dominated by TV and the Internet, where the simple transmission of data is not enough, it might be more correct to say Communicate or perish. Communicating your discoveries and techniques to the rest of the scientific community could improve the lives of millions of people and, less nobly, give your career a boost and earn you endless research funds. However, it isn’t easy to communicate fluently and elegantly when the language you have to use is not your own.

The course aims to show how you can use English as a tool-of-the-trade in the same way that you might eventually use a stethoscope or a microscope. There will be numerous suggestions on how to prepare for and deliver an oral presentation at a congress to a peer audience and how to survive the dreaded question-time session. IT lab sessions will focus on effective slide creation.

The main part of the course will be dedicated to student group and individual oral presentations where the theoretical skills previously examined will be put into practice. During this phase, the rest of the class will be expected to participate actively by asking questions re the subject of the presentation itself and carrying out overall peer review of the structure and delivery of the work.

Statistics in Bioresearch

Prof. Riccardo Fesce, Insubria University (July 2017)

Most theoretical aspects will be touched by discussing the statistical problems and experimental data proposed by the students.

“Regeneration” , SRSI - Nature Conference

from November 16th to November 18th.

The conference is organized in collaboration with Nature Journal. To find all useful information, visit the official website:

PhD Students Invited Lecture: Unraveling the Antibody Repertoire - Prof. Antonio Siccardi

March 10, 2016 – 17:00, room Agnodice (Dibit1)



Hands on - Translational Genomics and Bioinformatics

Course Objectives

  • This course aims at following small groups of PhD students for a year to provide them with essential but robust tools to address the most common questions asked by a quantitative analysis of of biological
  • In particular, the students will analyze RNA-seq data, ChIP-seq and exome At the beginning of the course the intermediate and final educational goals will be defined and they will be evaluatedby appropriate written assessments.

Course Structure

  • The course is structured in bi-weekly meetings with the bioinformaticians of CTGB in the period from January to October The experts will introduce a theme, illustrate the bioinformatics tools to be adopted, and assign analyzes to be carried out individually by the course participants in the following two weeks.
  • At the next meeting, the performance of individual students will be evaluated, the difficulties will be analyzed, and a new theme will be It is important to note that the tutors will remain available during the two weeks of individual work, although students will be encouraged to self-­‐”problem- solving” (either individually or as a group), before seeking the tutors’help.
  • Participants will be trained to the use of bioinformatics platforms and interactive programming using
  • Periodically, external experts will also be invited to introduce participants to the most popular platforms and bioinformatics tools including R Studio, Galaxy, G en Hub, Docker and advanced pathway Even in these cases, tutors will assign the tasks to be performed individually to the course participants.
  • After completing the course, a final exam will take place to assess the achievement by students of the goals originally

“Sympathy for the Devil”: How Technology Transfer Can Boost Your Research

Course Objectives

A 2-days PhD course on technology transfer from academia to industry and on how reiterative cycles thereof may profit both parties in the collective effort towards innovation.

The course will be organized in 1-hr lectures (45’ plus question time) from the different figures involved in the process, with the idea of having a variety of point-of-views (POVs) on the subject.

Course Structure

The lectures will be delivered in the mornings, while the afternoons will be devoted to interactive activities between students and lecturers.

Day 1. POVs:

The Scientist (Attilio Bondanza, UniSR)

The Technology Transfer Officer (Paola Pozzi, OSR)

Coffee break

The Patent Attorney (Simon O’Brien, D&Young IP, London)

The Lawyer (Valentina Bonomo, Studio Lombardi, Molinari e Segni, Milano)

Lunch (speakers only)

From 14,30 to 17,30: selected case studies presented and discussed by the speakers within small groups

18,00. End of day 1, get together event with the students at the “Faculty Club”. Speakers Dinner

Day 2. POVs

The Business Planner (Marija Zecevic, Proteostasis, Milano)

The Bioentrepreneur (Pierluigi Paracchi, Genenta Science, Milano)

Coffee break

The Biotech (Claudio Bordignon, MolMed Spa, Milano)

The Big Pharma (Pablo Umana to be confirmed, Roche-Glycart, Zurich)

Lunch (speakers only)

From 14,30 to 17,30: selected case studies presented and discussed by the speakers within small groups.


Advanced MR Techniques in Neuroradiology

April 10th, 2017, 14:30

14.30-15 – Visit to 3T scanner (Prof. A. Falini)

15-15.30 – Diffusion MRI, basic principles (Antonella Castellano)

15.30-16 – Diffusion MRI, clinical application (Antonella Castellano)

16-16.30 – Perfusion MRI, basic principles (Gian Marco Conte)

16.30-17 – Perfusion MRI, clinical application (Nicoletta Anzalone)

17-18 Practical workshop:

DTI and tractography (A. Castellano, A. Iadanza )

T1 and T2* MR perfusion (Gian Marco Conte)

Sede: Auletta di Neuroradiologia, settore C piano -2

In-vivo Imaging in Preclinical research

22nd June, 2017

14.00 Carlo Tacchetti – SRSI Experimental Imaging Center: rationale and organization

14.20 Antonio Esposito – MRI

14.40 Spinelli Antonello – Optical Imaging

15.00 Massimo Venturini – Ultrasonography

15.20 Gianpaolo Zerbini – Small Rodent eye’s imaging

15.40 Rosamaria Moresco – PET/SPECT based translational molecular imaging


16.20 Linda Chaabane – Novel MRI methods for pH and cellular imaging

16.35 Antonello Spinelli – Small animal image-guided radiotherapy systems

16.50 Laura Perani – Echocardiography in mice

17.05 Palmisano Anna – Multiparametric MRI of skeletal muscles in mice

17.20 Flavio Curnis – Assessment of tumor microvessels: the contribute of In-vivo imaging

17.35 Antonella Castellano – Multiparametric MRI in pdx models of gioblastoma.

17.50 Preclinical Imaging Facility visit

Genomics in the clinic

29th and 30th June, 2017

The aim of this course is to provide an overview of Next Generation Sequencing techniques and their translation to a clinical diagnostics context.

Main topics:

  • Next Generation Sequencing (NGS). The NGS revolution: comparison with standard Sanger sequencing; NGS platform overview and comparison (454, Solid, Illumina, Ion Torrent); overview of the NGS applications applied in a clinical diagnostics context (whole-­‐genome sequencing, targeted re-­‐sequencing, RNA-­‐seq and DNA methylation analysis).
  • NGS applications: focus on DNA Whole-­‐genome sequencing, whole-­‐ exome sequencing, gene panels: technical features and comparison. Examples of translation into clinical diagnostics: NGS in cohort genetics and genetic predisposition studies; radiogenomics; development of predictive and prognostic biomarkers.
  • Bioinformatics analysis of whole-­‐exome sequencing data. Introduction to the bioinformatics pipeline of whole-­‐exome sequencing data; examples of analysis output and interpretation (genome browsers and genetic variant lists).
  • Clinical microbiomics: understanding bacterial diversity through 16S rRNA and whole genome Clinical applications: the role of human microbiota in disease development; sequencing of bacterial pathogens.
  • NGS applications: focus on RNA Technical features and comparison of different RNA-­‐seq techniques, and introduction to the bioinformatics pipeline; examples of translation of RNA sequencing into clinical diagnostics.

The Course will be 12 hours long, on two consecutive days.


Genome Editing: technology, applications and ethical implications

9th November

 09:30 – 13:00  Morning session

09:30 – 10:15  Opening remarks and introduction to genome editing – Luigi Naldini, SR-Tiget

10:15 – 11:00  Targeted editing of the (epi)genome: technological aspects and applications – Angelo Lombardo, SR-Tiget

11:30 – 12:15  Innate Immunity and Vector Sensing in HSPC: Implications for Gene Editing – Anna Kajaste-Rudnitski, SR-Tiget

12:15 – 13:00  Artificial Nucleases in HSPCs: understanding the biology for better cellular products – Raffaella Di Micco, SR-Tiget

14:30 – 16:00  Afternoon session

Journal club (for CMP students; moderator: Cecilia Cotta-Ramusino, Editas Medicine)


10th November

09:30 – 12:30  Morning session

09:30 – 10:15  Genome editing: a company perspective – Cecilia Cotta-Ramusino, Editas Medicine

10:15 – 11:00  Ethical implications of genome editing applications – Giuseppe Novelli, Università degli Studi di Roma “Tor Vergata”

11:30 – 12:30  Round table (moderator: Giuseppe Novelli, Università degli Studi di Roma “Tor Vergata”)


Organizing committee:

Luigi Naldini – SR-Tiget

Angelo Lombardo – SR-Tiget

Federica Basilico – SR-Tiget

Attività didattica a.a. 2015/2016


From Transplantation to Gene Therapy: Cellular therapy in evolution

From Transplantation to Gene Therapy: Cellular therapy in evolution
The EBMT Cellular Therapy and Immunobiology Workin Party Symposium
November 11th – 13th, 2015

Cell-to-Cell Communication

Cell-to-Cell Communication
From November 31st to December 3rd , from 9:00 am
Room: Pinta (Dibit1)

Using English to communicate biomedical science 2016

from February 16th to April 14th – 17:30 – 18:30

New insights into muscle stem cell regenerative dysfunction with aging

Pura Munoz-Canoves (Pompeu Fabra University, Barcelona) – lunch with PhD students
February 19, 2016 – 1:00 pm
Room: 4A1 (Dibit1)

PhD Students Invited Lecture: Unraveling the Antibody Repertoire - Prof. Antonio Siccardi

March 10, 2016 – 17:00, room Agnodice (Dibit1)


March 18-20, 2016
Baveno (Hotel Dino)

Principi e strumenti di qualità nella ricerca scientifica

Principi e strumenti di qualità nella ricerca scientificaIng Antonella Lanati
April 4-8, 2016 – 9:30-13:30, 14:30-18:30
Room: Salk (Dibit1)

Science publishing – Behind the scenes at Nature

Public lecture: Science publishing – Behind the scenes at Nature
Francesca Cesari, Chief Biological Science Editor of Nature (International weekly Journal of Science)
April 11, 2016 – 14:30
Room: San Rafaele

Phospholipid related disorders: gene discovery in mouse and human

Teaching lecture: Phospholipid related disorders: gene discovery in mouse and human
Miriam Meisler – Professor of Human Genetics and Professor of Neurology at the University of Michigan, Ann Arbor
May 3, 2016 – 11:00
Room: Pinta (Dibit1)

Changing the Face of Modern Medicine: Stem Cells & Gene Therapy

Attività didattica a.a 2014/2015


Web Tools for the Analysis of Gene Function, Expression and Regulation

Web Tools for the Analysis of Gene Function, Expression and Regulation – Courses of Bioinformatics
Wednesday, 25th February 2015
Friday, 27th February 2015
Wednesday, 4th March 2015
Friday, 6th March 2015
Wednesday, 11th March 2015
Hours: 14:00-16:00

Corsi comuni ai seguenti Curricula: Biologia e Bioterapia del Cancro, Biologia Cellulare e Molecolare, Immunologia di Base e Applicata e Neuroscienze

Using English to communicate biomedical science 2015
From 17th March to 7th May
Lessons on Tuesdays and Thursdays, 17.30-18.30

Molecular Biology of Prions – PhD-Students-Invited Lecture
Prof. Adriano Aguzzi
April 24th 2015
From 10:00 am – Laboraf meeting room (Dibit2, Building San Gabriele, floor -1)

Antibody Based Cancer Immunotherapy – PhD Students invited lecture
Dr. Christian Klein – Head Oncology Programs at Roche Pharmaceutical Research and Early Development, Oncology Discovery & Translational Area, Roche Innovation Center Zurich – Schlieren, Switzerland.
Friday May, 29th 2015
at 3:00pm in Aula Caravella Pinta

Cell-to-Cell Communication
From November 31st to december 3rd , from 9:00 am
Room: Pinta (Dibit1)


Career Management Course
3rd and 4th March 2015
Partecipacipazione estesa anche ai dottorandi del curriculum in Neuroscienze


Principles of Exoperimental Neurology
Every Tuesday from October 20th to November 17th, 9:00 am
Room: San Paolo (DiMeR)

Attività didattica a.a 2013/2014


“Where Will a Career in Science Take You?”

“Where Will a Career in Science Take You?”
Prof. S. Bertuzzi September 25th (16:00-18:30)

Statistics in Bioresearch

Statistics in Bioresearch
September 17th and 24th (9.30-12.30)

Using English to Communicate Biomedical Science

Science meets European Patent Office

Science meets European Patent Office
November 27th 2014 – Aula San Paolo

Protein Folding Homeostasis in the endoplasmic reticulum

Protein Folding Homeostasis in the endoplasmic reticulum – Plenary Lecture
November 27th 2014 – Aula Caravella Pinta

RNA localization for Cell Size Regulation

RNA localization for Cell Size Regulation – Pleanary Lecture
December 1st 2014 – Aula Leonardo

Functional Analysis of melanoma driver genes

Functional Analysis of melanoma driver genes – Plenary Lecture
December 2nd 2014

Normal and Neoplastic Stem Cells

Normal and Neoplastic Stem Cells – Leonardo Lecture
Irving L. Weissman
February 4th, 2015 – Aula San Raffaele (10:00 am)


Permanent Education in Immunology (PEI)
on Wednesdays

Workshop “Imaging the Immune System”
with Italian-Swiss Immunological Societies
October 23rd and 24th 2014


Cell Biology of Disease June 30th – July 4th, 2014



Corso di Statistica


Students Workshop2014 PhD Meeting
November 7th and 8th – Camogli

Molecular Oncology Lectures – Plenary Seminar
Hassan Jumaa
November 25th, 2014 (10.30 am)

Career Managment
March 3rd and 4th, 2015 (Room Nina, 9:00 am)

Il Corso di Dottorato di Ricerca Internazionale in Medicina Molecolare
a partire dall’a.a. 2015/2016 si articola in 4 Curricula: