Massimo Alfano was born in Bergamo, Italy, in 1967, and obtained both his Degree in Biological Science at the University of Milan in 1992, where he also received his PhD in 2001. Since 1995, he has been involved with AIDS research in the AIDS Immunopathogenesis Unit of the San Raffaele Scientific Institute. From 1997 to 2000 he was Visiting Scientist in the Laboratory of AIDS Molecular Biology, lead by Michael Bukrinsky, at the Picower Institute in NY, USA. Since 2001 Massimo Alfano is a Staff Scientist in the AIDS Immunopathogenesis Unit of the San Raffaele Scientific Institute. He is author of more than 50 scientific articles and reviews published on international peer-journals.
Massimo Alfano is coordinating projects aimed to the comprehension of cellular factors modulating HIV infection, with the scope of identifying restriction factors (i.e., proteins or receptors) that could help in the characterization of viral latency and expression. Targeting cellular rather than viral genes may have advantages in terms of conservation of the gene and lack of selection of viral resistant mutants in comparison to canonical anti-retroviral therapy.