Maltecca Francesca Ricercatore a tempo determinatoMedicinaMED/03

Biografia

Pubblicazioni

English version

Biografia

Education

2008: PhD in Molecular Medicine, University Vita-Salute San Raffaele, Milan.

2003: Master’s degree in Pharmaceutical Biotechnologies (magna cum laude), University of Milan.

 

Professional Experiences

2019: Project Leader, Ospedale San Raffaele.

2014-2018: Researcher in Medical Genetics (MED/03), Università Vita-Salute San Raffaele.

2008-2013: Postdoc, Neurogenomics Unit, San Raffaele Scientific Institute, G. Casari’s lab.

2007-2008: Visiting scientist, Aarhus University Hospital Skejby, Denmark, P. Bross lab.

2004-2008: PhD student in Molecular Medicine (section of Neuroscience), University Vita-Salute San Raffaele, G.Casari’s lab.

2003-2004: Fellow, University of Milano-Bicocca, M.L. Lavitrano’s lab.

2002-2003: Undergraduate student, San Raffaele Scientific Institute, A. Servadio’s lab.

 

Grants

2019: Research Grant from Ataxia Charlevoix-Saguenay Foundation, Montreal Québec, Canada.

2018-2021: Bando 2016 Ricerca finalizzata, Italian Ministery of Health.

2018: OSR Seed Grant, Ospedale San Raffaele.

2016-2018: Research Grant from Ataxia Charlevoix-Saguenay Foundation, Montreal Québec, Canada. ".

2014-2017: Giovani Ricercatori, bando 2011-2012 from the Italian Ministery of Health.

2012-2014: Young Investigator Award for the SCAs Research, from National Ataxia Foundation, Minneapolis (USA).

 

Teaching appointments

2017-present: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Master degree in Biotechnology and Medical Biology, Course “Molecular Cell Biology”.

2016-present: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Master Degree in Medicine and Surgery, Course of Genetics and Developmental Biology.

2017-2018: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Bachelor Degree in Medical and Pharmaceutical Biotechnology, Course of Genetics and Molecular Biology part II.

2011-2018: Lecturer at the School of Medicine, University Vita-Salute San Raffaele, Bachelor Degree in Nursing, Coordinator of the Course “Fondamenti Biomolecolari della vita”.

2015-2017: Tutor at the School of Medicine, Università Vita-Salute San Raffaele, Bachelor Degree in Medical and Pharmaceutical Biotechnology, Course of Genetics and Molecular Biology part II.

2013-2017: Tutor at the School of Medicine, Università Vita-Salute San Raffaele, International MD Program, Course of Genetics and Developmental Biology

Pubblicazioni

Publications

Duncan EJ, Larivière R, Bradshaw TY, Longo F, Sgarioto N, Hayes MJ, Romano LEL, Nethisinghe S, Giunti P, Bruntraeger MB, Durham HD, Brais B, Maltecca F, Gentil BJ, Chapple JP. Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin. Hum Mol Genet. 2017 Aug 15;26(16):3130-3143.

Maltecca F, Baseggio E, Consolato F, Mazza D, Podini P, Young SM Jr, Drago I, Bahr BA, Puliti A, Codazzi F, Quattrini A, Casari G. Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model. J Clin Invest. 2015 Jan;125(1):263-74.

Mancini C, Roncaglia P, Brussino A, Stevanin G, Lo Buono N, Krmac H, Maltecca F et al. Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. BMC Med Genomics. 2013 Jun 18;6(1):22.

Magnoni R, Palmfeldt J, Christensen JH, Sand M, Maltecca F, Corydon TJ, West M, Casari G, Bross P. Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice. Neurobiol Dis. 2013 Jun;54:12-23.

Maltecca F, De Stefani D, Cassina L, Consolato F, Wasilewski M, Scorrano L, Rizzuto R, Casari G. Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation. Hum Mol Genet. 2012 Sep 1;21(17):3858-70.

Maltecca F, Magnoni R, Cerri F, Cox GA, Quattrini A, Casari G.     Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia            type 28, causes mitochondria-mediated Purkinje cell dark degeneration. J Neurosci. 2009 Jul 22;29(29):9244-54.

Maltecca F, Aghaie A, Schroeder DG, Cassina L, Taylor BA, Phillips SJ, Malaguti M, Previtali S, Guénet JL, Quattrini A, Cox GA, Casari G. The mitochondrial protease AFG3L2 is essential for axonal development. J Neurosci. 2008 Mar 12;28(11):2827-36.

Maltecca F, Filla A, Castaldo I, Coppola G, Fragassi NA, Bruni A, Cocozza S, Casari G, Servadio A & De Michele G. Intergenerational instability and marked anticipation in SCA17. Neurology 2003; 61(10):1441-3.

 

 

 

English version

Curriculum vitae

Education

2008: PhD in Molecular Medicine, University Vita-Salute San Raffaele, Milan.

2003: Master’s degree in Pharmaceutical Biotechnologies (magna cum laude), University of Milan.

Professional Experiences

2014-present: Researcher in Medical Genetics (MED/03), Università Vita-Salute San Raffaele.

2008-2013: Postdoc, Neurogenomics Unit, San Raffaele Scientific Institute, G. Casari’s lab.

2007-2008: Visiting scientist, Aarhus University Hospital Skejby, Denmark, P. Bross lab.

2004-2008: PhD student in Molecular Medicine (section of Neuroscience), University Vita-Salute San Raffaele, G.Casari’s lab.

2003-2004: Fellow, University of Milano-Bicocca, M.L. Lavitrano’s lab.

2002-2003: Undergraduate student, San Raffaele Scientific Institute, A. Servadio’s lab.

Grants

2016-2018: Research Grant from Ataxia Charlevoix-Saguenay Foundation, Montreal Québec, Canada. “.

2014-2017: Giovani Ricercatori, bando 2011-2012 from the Italian Ministery of Health.

2012-2014: Young Investigator Award for the SCAs Research, from National Ataxia Foundation, Minneapolis (USA).

Teaching appointments

2017-present: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Master degree in Medical, Molecular and Cellular Biotechnology, Coordinator of the course “Organellar Pathology”.

2017-present: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Bachelor Degree in Medical and Pharmaceutical Biotechnology, Course of Genetics and Molecular Biology part II.

2016-present: Lecturer at the School of Medicine, Università Vita-Salute San Raffaele, Master Degree in Medicine and Surgery, Course of Genetics and Developmental Biology.

2011-present: Lecturer at the School of Medicine, University Vita-Salute San Raffaele, Bachelor Degree in Nursing, Coordinator of the Course “Fondamenti Biomolecolari della vita”.

2015-2017: Tutor at the School of Medicine, Università Vita-Salute San Raffaele, Bachelor Degree in Medical and Pharmaceutical Biotechnology, Course of Genetics and Molecular Biology part II.

2013-2017: Tutor at the School of Medicine, Università Vita-Salute San Raffaele, International MD Program, Course of Genetics and Developmental Biology.

Il titolare del presente curriculum vitae, pubblicato online sul portale www.unisr.it, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.