Bio

Professor of Neurosurgery – MD, Specialist in Neurosurgery and ENT Surgery

 

Clinical Activity

 

01/10/2008 to date

Chairman Department of Neurosurgery and Radiosurgery

Scientific Institute San Raffaele, Milan (ITALY)

11/01/2005 – 01/09/2008

Chairman Department of Neurosurgery

Spedali Civili Hospital, Brescia (ITALY)

01/10/2005 – 01/09/2008

Consultant Neurosurgeon at the Department of Neurosurgery

Scientific Institute San Raffaele, Milan (ITALY)

2002

Director Skull Base Surgery Section, Department of Neurosurgery

Scientific Institute San Raffaele, Milan (ITALY)

2001

Senior Active Staff member, Department of Neurosurgery

Scientific Institute San Raffaele, Milan (ITALY)

1996 – 2005

Consultant Neurosurgeon at the Department of Neurosurgery

Lodi County Hospital, Lodi (ITALY)

1992 – 2000

Active Staff member, Department of Neurosurgery

Scientific Institute San Raffaele, Milan (ITALY)

1986 – 1991

Resident in Neurosurgery, Department of Neurosurgery

University of Verona, Verona (ITALY)

 

 

Research Activity

 

Publications

Author of more than 200 publications, mainly of international level

 

Experimental Activities

Head Unit of Experimental Neurosurgery

– Pre-Clinical study on olfactory cell transplantation in spinal cord injuries (Grant of Regione Lombardia “Autologous olfactory ensheathing cell transplantation in humans with spinal cord injuries: an international phase 2 multicentric clinical trial” – 2011/2012)

– Pre-clinical study on use of collagen scaffold in spinal cord and peripheral nerves injuries (PON #2 – RINOVATIS)

 

 

Collaborations

2005 to date

Collaboration with the Department of Bioengineer University of Lecce (ITALY), Harvard Medical School, Boston (USA), Massachussets Institute of Technology Boston (USA) and Dept. of Neurology – Vita-Salute San Raffaele University Milano (ITALY) for the research on applications of collagen scaffolds for the treatment of nervous system injuries.

2000 to date

Collaboration with the Institute of Medical Genetics at the University of Milano to study the cytogenetic of skull base chordomas.

1996 to date

Collaboration with the Max Plank Istitut für Psychiatrie of Munchen (GERMANY) to study the pathology of the pituitary tumors.

1992 to date

Collaboration with the Chair of Maxillo-facial surgery of the University of Milan for the research on new surgical technique for the treatment of cranio-facial malformation and cranio-facial tumors.

1992 to date

Member of the Pituitary Unit (research unit officially recognized by the International Advisory Board of the Neuroscience Department of the San Raffaele Scientific Institute).

 

Active Collaborations

Clinical and Basic Research

Dept. of Neurology, Dept. of Neurosurgery, Dept. of ENT Surgery, Dept. of Endocrinology and Dept. of Pathology at the University Vita-Salute San Raffaele University Milan (ITALY)

Max-Planck-Institut für Psychiatrie, Munchen (GERMANY)

Dept. of Maxillo-Facial Surgery, Institute for Medical Genetics at the University of Milan (ITALY)

The George Washington University Washington DC (USA) Harvard Medical School, Boston (USA)

Massachussets Institute of Technology Boston (USA)

Department of Bioengineer University of Lecce (ITALY)

 

 

Scientific Societies

1998 – 2005

Member of the Scientific Committee of the Italian Skull Base Society

 

Memberships

Congress of Neurological Surgeons (USA)

European Society for Skull Base Surgery

Italian Society for Skull Base Surgery

Italian Society for Neurosurgery

Consultant Neurosurgeon at the Department of Neurosurgery Lodi County Hospital, Lodi (ITALY)

 

Scientific Reviewer

Pituitary (PITU), Editor-in-Chief Dr. Shlomo Melmed

 

Academic appointments and Teaching activity

 

University

2014

Director, International University Master in Radiosurgery, Vita-Salute San Raffaele University – School of Medicine, Milano (ITALY)

15/07/2011 to date

Member of the Dean Committee of the Vita-Salute San Raffaele University – School of Medicine, Milano (ITALY)

2010 to date

Member of the Technical Commission – Cooperation Agreement between the University of Extremadura (Spain) and Vita-Salute San Raffaele University (Italy)

2012 to date

Member of the Technical Commission – Cooperation Agreement between the George Washington University (USA) and Vita-Salute San Raffaele University (Italy)

01/17/2008 to date

Director Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)

01/10/2008 to date

Full time professor, Vita-Salute San Raffaele University, Milan (ITALY)

2007 to date

Clinical Professor of Neurosurgery

The George Washington University Neurological Institute, Washington D.C. (USA)

2005 – 2008

Director Residency Program in Neurosurgery, University of Brescia (ITALY)

2005 – 2008

Full time professor, University of Brescia (ITALY)

2004 – 2005

Associate Professor of Neurosurgery, University of Brescia (ITALY)

2004 – 2005

Professor of Clinical Neuroanatomy, Vita-Salute San Raffaele University, Milan (ITALY)

September 2004

Visiting Professor of Neurosurgery, Residency Program

The George Washington University Neurological Institute, Washington D.C. (USA)

October 2002

Visiting Professor of Neurosurgery, Residency Program

The George Washington University Neurological Institute, Washington D.C. (USA)

2000 – 2002

Professor of Clinical Neurosurgery

School of Medicine, Vita-Salute San Raffaele University, Milan (ITALY)

2000 – 2002

Professor of Surgical Anatomy of the Skull and Brain

School of Medicine, Vita-Salute San Raffaele University, Milan (ITALY)

2000 – 2002

Professor of Clinical Neurosurgery,

Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)

1995 – 2000

Tutor of Clinical Neurosurgery

Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)

1999 – 2000

Tutor of Neurosurgery at the School of Medicine and Residency Program

University of Milan (Policlinic Hospital, San Raffaele Hospital, Sacco Hospital), University of Milano

Bicocca (San Gerardo Hospital, Monza) (ITALY)

1994 – 2000

Instructor of Neuroanatomy, Chair of Human Anatomy

University of Milan, Milan (ITALY)

1992 – 1996

Instructor of Neuroanatomy

Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)
Italian Ministry of Health

2010-2011

Member of the Joint Commission for cooperation between Italy and Malta

2011

Consultant for the Italian Ministry of Health for neurosurgery and tissue engineering

 

 

School of Nursing

1990 – 1996

Professor of Neurosurgery at the School of Nursing at the Verona University Hospital and at the San Raffaele University Hospital in Milan (ITALY)

 

Post-graduated courses

Organizer, instructor, lecturer in more than 45 courses in Italy and abroad.

(see annex I/02 for detailed description)

 

 

Education and training     

1980

High School leaving Certificate, Classical Lyceum

1986

First Class medical degree Cum Laude and university honour

 

 

Licensure and Certification         

2005

Swiss licence to practice medicine and surgery in the specialty of neurosurgery

2000

Specialty in ENT Surgery with top marks

University of Milan, Milan (ITALY)

1991

Specialty in Neurological Surgery with top marks

University of Verona, Verona (ITALY)

1986

Italian license to practice medicine and surgery with top marks

University of Parma, Parma (ITALY)

 

 

Postdoctoral Training

 

Courses attended IN ITALY

1997

8th course in vascular surgery techniques, Milan (ITALY)

1996

International course on intra-operative cranial nerves monitoring

Italian Society for Skull Base Surgery, Parma (ITALY)

1995

Cranio-cervical junction surgery, Italian Society for Skull Base Surgery, Milan (ITALY)

1995

Trans-craniofacial approaches, Italian Society for Skull Base Surgery, Rome (ITALY)

1994

Lateral approaches to the skull base, Piacenza (ITALY)

 

1991

International Course on Transcranial Doppler, Montesilvano (PE,ITALY)

1991

4th microsurgery workshop, Microsurgical Research Institute, Prato (ITALY)

1991

Annual course of the Italian Society for Neurosurgery, Abano (PD, ITALY)

1989

Annual course of the Italian Society for Neurosurgery, Abano (PD, ITALY)

1988

Cerebral arterio-venous malformations, Verona (ITALY)

1987

Cerebral aneurysms: imaging, Verona (ITALY)
Courses attended OUTSIDE ITALY

1999

Congress of the American Association of Neurological Surgeons, New Orleans (USA)

Antero-lateral approaches to tumors and aneurysms (Credit 4), Cavernous sinus surgery (Credit 2),

Angiografically occult vascular malformations (Credit 2), Lateral skull base (Credit 2), Intracranial endoscopy (Credit 2)

1996

Course de chirurgie de la base du crâne (Prof Magnan), Marseille (FRANCE)

1996

5th practical course in Microsurgery of the Skull Base (Prof. Fish), Zurich (SWITZERLAND)

1995

Workshop on the vertebral artery (Prof. George), Paris (FRANCE)

1992

International course on clinical neurosurgery (Prof. Samii), Hannover (GERMANY)

 

 

 

Focus Clinical and Research

Educational Experiences

1999

International Fellowship. Research activity at the Minimally Invasive Surgery skull Base Training Center on microsurgical and endoscopic skull base approaches for clival tumors, vascular microsurgical and

EC/IC by-pass training. Prof L. N. Sekhar, Department of Neurosurgery, The George Washington University Neurological Institute, Washington D.C. (USA)

 

1995

Training on the surgical techniques for the control of vertebral artery in the treatment of vascular and tumoral pathologies of the skull base, the cranio cervical junction and the cervical spine. Prof. B.George, Department of Neurosurgery, Hôspital Lariboisiére, Paris (FRANCE).

1989

Experimental and clinical researches on calcium channel blockers in SAH related vasospasm, Prof N. Kassel. Training in Stereotactic radiosurgery, Prof. L. Steiner. Department of Neurosurgery, Virginia University, Charlottesville (USA).

1986

Training in Neurotrauma, Prof Miller D, Department of Neurosurgery, Western General Hospital, University of Edinburgh, Edinburgh (UK).

 

  

Personal skills and Competences                                 

2008 Surgical instruments set for microsurgery of skull base.

See: K. Storz catalogue – Instruments according to Prof. P. Mortini

2012 Patent: Collagen Scaffold in nervous system regeneration. AS 34576

 

 

Technical skills and competences

competences                    4262 surgical procedures performed, mainly for skull base, brain and spine tumors and cerebrovascular disorders.

Stereotactic Gamma Knife radiosurgical procedures since 1994

Boari N, Spina A, Giudice L, Gorgoni F, Bailo M, Mortini P (2018) Fronto-orbitozygomatic approach: functional and cosmetic outcomes in a series of 169 patients. J Neurosurg. 128: 466-74

Mortini P., Barzaghi L.R., Albano L., Panni P, Losa M (2018) Microsurgical therapy of pituitary adenomas. Endocrine. 59: 72-81

Della-Torre, E; Campochiaro, C; Cassione, EB; Albano, L; Gerevini, S; Bianchi-Marzoli, S; Bozzolo, E; Passerini, G; Lanzillotta, M; Terreni, M; Callea, M; Trimarchi, M; Mortini, P; Tresoldi, M; Acerno, S; Dagna, L (2017) Intrathecal rituximab for IgG4-related hypertrophic pachymeningitis. J Neurol Neurosurg Psychiatry. 89:441-4

Ferrari L, Pistocchi A, Libera L, Boari N, Mortini P, Bellipanni G, Giordano A, Cotelli F, Riva P (2014) FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation. Oncotarget. 5:5712-24

Mortini P, Gagliardi F, Boari N, Losa M (2013) Surgical strategies and modern therapeutic options in the treatment of craniopharyngiomas. Critical Reviews in Oncology/Hematology. 88:514-29

Losa M, Picozzi P, Redaelli MG, Laurenzi A, Mortini P (2010) Pituitary radiotherapy for Cushing’s disease. Neuroendocrinology. 92: 107-10

Di Tomaso T, Mazzoleni S, Wang E, Sovena G, Clavenna D, Franzin A, Mortini P, Ferrone S, Doglioni C, Marincola FM, Galli R, Parmiani G, Maccalli C. (2010) Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res. 16:800-13

Valassi E, Biller BM, Swearingen B, Pecori Giraldi F, Losa M, Mortini P, Hayden D, Cavagnini F, Klibanski A. J (2010) Delayed remission after transsphenoidal surgery in patients with Cushing’s disease. Journal Clin Endocrinol Metab. 95:601-10

Losa M, Bianchi R, Barzaghi R, Giovanelli M, Mortini P. (2009) Persistent adrenocorticotropin response to desmopressin in the early postoperative period predicts recurrence of Cushing’s disease. J Clin Endocrinol Metab. 94:3322-28

Losa M, Gioia L, Picozzi P, Franzin A, Valle M, Giovanelli M, Mortini P (2008) The role of stereotactic radiotherapy in patients with growth hormone-secreting pituitary adenoma. J Clin Endocrinol Metab. 99:2546-52

 

I siti personali del Prof. Mortini sono:

http://www.pietromortini.com
http://www.ipofisi.com

Professor of Neurosurgery

Chairman Department of Neurosurgery, San Raffaele Scientific Institute

 

First Class Medical Degree – University of Parma – 1986

Speciality in Neurological Surgery – University of Verona – 1991.

Speciality in ENT Surgery – University of Milano – 2000.

 

University

17/01/2008 to date

Director Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan

1/02/2008 to date

Professor of Clinical Neurosurgery at The George Washington University, Neurological Institute, Washington D.C. (USA)

10/01/2008 to date

Full time professor, Vita-Salute San Raffaele University, Milan

2005 – 2007

Director Residency Program in Neurosurgery, University of Brescia, Verona (ITALY)

2004 – 2007

Full time professor, University of Brescia, Verona (ITALY)

2004 – 2005

Associate Professor of Neurosurgery, University of Brescia (ITALY)

2004 – 2005

Professor of Clinical Neuroanatomy, Vita-Salute San Raffaele University, Milan (ITALY)

September 2004

Visiting Professor of Neurosurgery, Residency Program The George Washington University Neurological Institute, Washington D.C. (USA)

October 2002

Visiting Professor of Neurosurgery, Residency Program The George Washington University Neurological Institute, Washington D.C. (USA)

2000 – 2002

Professor of Clinical Neurosurgery School of Medicine, Vita-Salute San Raffaele University, Milan (ITALY)

2000 – 2002

Professor of Surgical Anatomy of the Skull and Brain School of Medicine, Vita-Salute San Raffaele University, Milan (ITALY)

2000 – 2002

Professor of Clinical Neurosurgery, Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)

1995 – 2000

Tutor of Clinical Neurosurgery Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan (ITALY)

1999 – 2000

Tutor of Neurosurgery at the School of Medicine and Residency Program University of Milan (Policlinic Hospital, San Raffaele Hospital, Sacco Hospital), University of Milano

Bicocca (San Gerardo Hospital, Monza) (ITALY)

1994 – 2000

Instructor of Neuroanatomy, Chair of Human Anatomy University of Milan, Milan (ITALY)

1992 – 1996

Instructor of Neuroanatomy Residency Program in Neurosurgery, Vita-Salute San Raffaele University, Milan

 

Clinic

01/10/2008 to date

Chairman Department of Neurosurgery Scientific Institute San Raffaele, Milan (ITALY)

11/01/2005 – 01/09/2008

Chairman Department of Neurosurgery Spedali Civili Hospital, Brescia (ITALY)

01/10/2005 – 01/09/2008

Consultant Neurosurgeon at the Department of Neurosurgery Scientific Institute San Raffaele, Milan (ITALY)

2002

Director Skull Base Surgery Section, Department of Neurosurgery Scientific Institute San Raffaele, Milan (ITALY)

2001

Senior Active Staff member, Department of Neurosurgery Scientific Institute San Raffaele, Milan (ITALY)

1996 to date

Consultant Neurosurgeon at the Department of Neurosurgery Lodi County Hospital, Lodi (ITALY)

1992 – 2000

Active Staff member, Department of Neurosurgery Scientific Institute San Raffaele, Milan (ITALY)

 

Collaborations

2005 to date

Collaboration with the Department of Bioengineer University of Lecce (ITALY), Harvard Medical Shool, Boston (USA), Massachussets Insitute of Technology Boston (USA) and Dept. of Neurology – Vita- Salute San Raffaele University Milano (ITALY) for the research on applications of collagen scaffolds or the treatment of nervous system injuries.

2005 to date

Collaboration with University of Brescia – Morphometric analysis of brain circulation

2000 to date

Collaboration with the Institute of Medical Genetics at the University of Milan to study the chordomas from the cytogenetic point of view.

1999 to date

Collaboration with The George Washington University – Neurological Institute (USA) – Development of new treatments for skull base lesions

1996 to date

Collaboration with the Max Plank Istitut für Psychiatrie of Munchen (GERMANY) to study the pathology of the pituitary tumors.

1992 to date

Collaboration with the Chair of Maxillo-facial surgery of the University of Milan for the research on new surgical technique for the treatment of cranio-facial malformation and cranio-facial tumors.

1992 to date

Member of the Pituitary Unit (research unit officially recognized by the International Advisory Board of the Neuroscience Department of the San Raffaele Scientific Institute).

Il titolare del presente curriculum vitae, pubblicato online sul portale www.unisr.it, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.