Criscuolo Elena Ricercatore a tempo determinatoMedicineMED/07 Microbiologia e Microbiologia clinica

Biography

Publications

Biography

Short narrative

Elena Criscuolo obtained her PhD in Molecular Medicine at the Vita-Salute San Raffaele University in 2016, working on the antibody response elicited during the Herpes Simplex Virus (HSV) infection and the protection conferred in vivo by human monoclonal antibodies. Then, she remained in Massimo Clementi’s laboratory of Microbiology and Virology as a postdoctoral research fellow, working on synergy evaluation of anti-herpetic compounds acting on different steps of the virus life cycle, on the characterization of sera from HSV infected subjects, and modeling HSV reactivation dynamics in a patterned human neuron-to-keratinocyte circuit reconstituted in a microfluidic device. Then, she focused her work also on the characterization of entry mechanisms of SARS-CoV-2, the evaluation of antiviral drugs against the infection, and the dissection of the humoral response of COVID-19 patients.

Unique identifiers

ORCID ID: 0000-0003-0185-3147

Scopus Author ID: 55372657000

Researcher ID: I-1918-2019

Google Scholar: https://scholar.google.com/citations?hl=it&user=AH3XXP5U4wkC

 

LinkedIn: linkedin.com/in/elena-criscuolo-3821b618

ResearchGate: researchgate.net/profile/Elena_Criscuolo/?ev=prf_act

 

Education

2016    Ph.D. in Molecular Medicine, Vita-Salute San Raffaele University, Milan (IT)

2011    Master’s Degree Course in Medical, Molecular and Cellular Biotechnology, Vita-Salute San Raffaele University, Milan (IT)

2009    Bachelor’s Degree Course in Medical and Pharmaceutical Biotechnology, Vita-Salute San Raffaele University, Milan (IT)

 

Positions and Training

2021 – oggi       Researcher (RTDa), Vita-Salute San Raffaele University, Milan (IT)

2016 – 2021      Postdoctoral Fellow, Vita-Salute San Raffaele University, Milan (IT)

 

 

Honors and Awards

2019           “La Torretta” Award, BCC Milan

2018           “Cecilia Cioffrese” Award, Carlo Erba Foundation

Professional Activities

Journal ReviewerAnnual Research & Review in Biology, International Journal of Molecular Sciences, Viruses, Microbial Pathogenesis, Vaccines, Microorganisms, Pathogens, Antibiotics, Journal of Clinical Medicine, Journal of Infection, Journal of Immunology Research, Microbiology Research Journal International

Editorial BoardEpidemiologia, Journal of Clinical Medicine (section Immunology), Microorganisms

Professional Societies

Member of Italian Society for Virology (SIV-ISV)

Teaching experience

Professor of the course of Clinical Microbiology the bachelor’s degree course in Obstetrics (Faculty of Medicine and Surgery) at Vita-Salute San Raffaele University for the A.Y. 2021/22.

Contract professor of the course of Microbiology at the bachelor’s degree course in Biotechnological Research in Medicine (Faculty of Medicine and Surgery) at Vita-Salute San Raffaele University for the A.Y. 2019/20, 2020/21, 2021/22.

Contract professor for the Professionalizing Activities (APRO) of laboratory technical skills at the master’s degree course in Medicine and Surgery for the A.Y. 2021/22.

(Nov. 2021)

Publications

FULL PAPERS

  1. Storti B, Quaranta P, Di Primio C, Clementi N, Mancini N, Criscuolo E, Speziax PG, Carnicelli V, Lottini G, Paolini E, Freer G, Lai M, Costa M, Beltram F, Diaspro A, Pistello M, Zucchi R, Bianchini P, Signore G, Bizzarri R (2021). A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in Vero E6 cells. Computational and Structural Biotechnology Journal (IF = 7.271)

 

  1. Della-Torre E, Criscuolo E, Lanzillotta M, Locatelli M, Clementi N, Mancini N, Dagna L, on behalf of theCOVID-BioB study group (2021). IL-1 and IL-6 inhibition affects the neutralising activity of anti-SARS-CoV-2 antibodies in patients with COVID-19. The Lancet Rheumatology – DOI: 10.1016/S2665-9913(21)00321-0 (IF = 8.136)

 

  1. Maugeri N, De Lorenzo R, Clementi N, Diotti RA, Criscuolo E, Godino C, Tresoldi C, Bio Angels for COVID-BioB Study Group, Bonini C, Clementi M, Mancini N, Ciceri F, Rovere-Querini P, Manfredi AA (2021). Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19. Journal of thrombosis and haemostasis – DOI: 10.1111/jth.15575 (IF = 5.824)

 

  1. Conforti A, Marra E, Palombo F, Roscilli G, Ravà M, Fumagalli V, Muzi A, Maffei M, Luberto L, Lione L, Salvatori E, Compagnone M, Pinto E, Pavoni E, Bucci F, Vitagliano G, Stoppoloni D, Pacello ML, Cappelletti M, Ferrara FF, D’Acunto E, Chiarini V, Arriga R, Nyska A, Di Lucia P, Marotta D, Bono E, Giustini L, Sala E, Perucchini C, Paterson J, Ryan KA, Challis A, Matusali G, Colavita F, Caselli G, Criscuolo E, Clementi N, Mancini N, Groß R, Seidel A, Wettstein L, Münch J, Donnici L, Conti M, De Francesco R, Kuka M, Ciliberto G, Castilletti C, Capobianchi MR, Ippolito G, Guidotti LG, Rovati L, Iannacone M, Aurisicchio L (2021). COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19. Molecular Therapy – DOI: 10.1016/j.ymthe.2021.09.011 (IF = 8.986)

 

  1. Severa M, Diotti RA, Etna MP, Rizzo F, Fiore S, Ricci D, Iannetta M, Sinigaglia A, Lodi A, Mancini N, Criscuolo E, Clementi M, Andreoni M, Balducci S, Barzon L, Stefanelli P, Clementi N, Coccia EM (2021). Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection. PLOS Pathogens – DOI: 10.1371/journal.ppat.1009878 (IF = 6.218)

 

  1. Ferrari D, Clementi N, Spanò SM, Albitar-Nehme S, Ranno S, Colombini A, Criscuolo E, Di Resta C, Tomaiuolo R, Viganó M, Mancini M, De Vecchi E, Locatelli M, Mangia A, Perno CF, Banfi G (2021). Harmonization of six quantitative SARS-CoV-2 serological assays using sera of vaccinated subjects. Clinica Chimica Acta – DOI: 10.1016/j.cca.2021.08.024 (IF = 3.786)

 

  1. Sposito B, Broggi A, Pandolfi L, Crotta S, Clementi N, Ferrarese R, Sisti S, Criscuolo E, Spreafico R, Long JM, Ambrosi A, Liu E, Frangipane V, Saracino L, Bozzini S, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Chou J, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I (2021). The interferon landscape along the respiratory tract impacts the severity of COVID-19. Cell – DOI: 10.1016/j.cell.2021.08.016 (IF = 41.582)

 

 

  1. Castelli M, Baj A, Criscuolo E, Ferrarese R, Diotti RA, sampaolo M, novazzi F, Dalla Gasperina D, Focosi D, Ferrari D, Locatelli M, Clementi M, Clementi N, Maggi F, Mancini N (2021). Characterization of a Lineage C.36 SARS-CoV-2 Isolate with Reduced Susceptibility to Neutralization Circulating in Lombardy, Italy. Viruses – DOI: 10.3390/v13081514 (IF = 5.048)

 

  1. Clementi N, Ghosh S, De Santis M, Castelli M, Criscuolo E, Zanoni I, Clementi M, Mancini N (2021). Viral Respiratory Pathogens and Lung Injury. Clinical Microbiology Reviews – DOI: 10.1128/CMR.00103-20 (IF = 24.43)

 

  1. Criscuolo E*, Diotti RA*, Ferrarese R, Alippi C, Viscardi G, Signorelli C, Mancini N, Clementi M, Clementi N (2021) Fast inactivation of SARS-CoV-2 by UV-C and ozone exposure on different materials. Emerging Micobes and Infections – DOI: 10.1080/22221751.2021.1872354 (IF= 5.776)

[*First authorship shared]

 

  1. Clementi N, Scagnolari C, D’Amore A, Palombi F, Criscuolo E, Frasca F, Pierangeli A, Mancini N, Antonelli G, Clementi M, Carpaneto A, Filippini A. (2020) Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro. Pharmacological Research – DOI: 10.1016/j.phrs.2020.105255 (IF= 5.893)

 

  1. Criscuolo E, Diotti RA, Strollo M, Rolla S, Ambrosi A, Locatelli M, Burioni R, Mancini N, Clementi M, Clementi N. (2020) Weak correlation between antibody titers and neutralizing activity in sera from SARS‐CoV‐2 infected subjects. Journal of Medical Virology – DOI: 10.1002/jmv.26605 (IF= 2.021)

 

  1. Caputo V, Diotti RA, Boeri E, Hasson H, Sampaolo M, Criscuolo E, Bagaglio S, Messina E, Uberti-Foppa C, Castelli M, Burioni R, Mancini N, Clementi M, Clementi N. (2020) Detection of low-level HCV variants in DAA treated patients: comparison amongst three different NGS data analysis protocols. Virology Journal – DOI: 10.1186/s12985-020-01381-3 (IF= 2.579)

 

  1. Clementi N, Criscuolo E, Diotti RA, Ferrarese R, Castelli M, Dagna L, Burioni R, Clementi M, Mancini N. (2020) Combined prophylactic and therapeutic use maximizes hydroxychloroquine anti-SARS-CoV-2 effects in vitro. Frontiers in Microbiology - DOI: 10.3389/fmicb.2020.01704 (IF= 4.236)

 

  1. Clementi N, Ferrarese R, Criscuolo E, Diotti RA, Castelli M, Scagnolari C, Burioni R, Antonelli G, Clementi M, Mancini N. (2020) Interferon-β 1a Inhibits SARS-CoV-2 in Vitro When Administered After Virus Infection. The Journal of Infectious Diseases - DOI: 10.1093/infdis/jiaa350 (IF= 5.022)

 

(Nov. 2021)

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