Della Torre Emanuel Ricercatore a tempo determinatoMedicineMED/16




A little profile

After receiving his Medical Degree, Board Certification in Allergy and Clinical Immunology, and PhD in Basic and Applied Immunology, Dr. Della Torre worked for 3 years in the United States at the “Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard Medical School” in Boston. Thanks to a Cariplo Foundation research grant, Dr. Della Torre returned to Italy in 2018 and established his lab within the Division of Genetic and Cell Biology of San Raffale Hospital (Milan, Italy). Dr. Della Torre is now Assistant Professor of Rheumatology at Vita-Salute San Raffaele University and Senior Consultant at the Unit of Immunology, Rheumatology, Allergy, and Rare Disease (UnIRAR) of San Raffaele Hospital.  Dr. Della Torre authored more than 100 scientific publications on international peer-reviewed journals and achieved prestigious awards such as the Collegio Ghislieri and the Cariplo Foundation awards for young researchers, the TRIDEO award, the MyFirst AIRC research grant, and the Career Research Grant Award from the FOREUM Foundation. With his seminal works Dr. Della Torre contributed to the characterization of a novel autoimmune disease known as “IgG4-related disease” and is currently considered “World Expert of IgG4-related disease” by the prestigious Expertscape platform. Up to September 2022, his scientific publications received more than 6000 citations with an H-index of 35. Dr. Della Torre presented his studies in different national and international immune-rheumatologic congresses, organized a number of scientific meetings, and co-authored 10 medical books. He presently serves as reviewer for more than 50 peer-reviewed journals and as associated editor for three international scientific journals.



2018 - PhD in Basic and Applied Immunology (Università Vita-Salute San Raffaele, Milan, Italy)

2014 - European Board Certification in Allergy and Clinical Immunology (Università Vita-Salute San Raffaele, Milan, Italy)

2008 – Medical Degree (Università Vita-Salute San Raffaele, Milan, Italy)


Academic Career

2021-present – Assistant Professor of Rheumatology (Università Vita-Salute San Raffaele, Milan, Italy)

2021-present – Member of the Scientific Board of the PhD Program in Clinical and Experimental Medicine (Università Vita-Salute San Raffaele, Milan, Italy)

2014-present - Invited Lecturer at Milano-Bicocca University, Padova University, Pavia University, Modena e Reggio Emilia University, Boston Harvard Medical School.

2017-2021 - Academic Researchers (Università Vita-Salute San Raffaele, Milan, Italy)

2018 - Tutor for the Immunology Program at Harvard Medical School (Boston, USA)

2014-2017 – Contract Professor (Università Vita-Salute San Raffaele, Milan, Italy)


Clinical Career

2020-present - Consultant Rheumatologist, Immunologist and Allergist at the Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR) (San Raffaele Hospital, Milan, Italy)

2014-2020 – Consultant Immunologist and Allergist at the Unit of Internal Medicine (San Raffaele Hospital, Milan, Italy)

2014-present – Head of the:

- IgG4-Related Disease Clinic

- Autoimmune pancreatitis Clinic

- Retroperitoneal Fibrosis Clinic

at San Raffaele Hospital (Milan, Italy)


Research Activity

2019-present – Principal Investigator / Group Leader (Division of Genetic and Cell Biology, San Raffaele Hospital, Milan, Italy)

2016-2018 - Post-doctoral research fellowship (The Ragon Institute of MGH, MIT, Harvard - Boston, USA)

2013-2014 - Research fellowship (Cancer Center del Massachussetts General Hospital - Boston, USA)

2007-2008 - Research fellowship (National Institutes of Health (NIH) - Bethesda, USA)



2022-present – Disease Coordinator of the IgG4-related disease European working group of the European Reference Network (ERN) on Rare Connective Tissue and Musculoskeletal Diseases (ReCONNET)

2009-present – Member of the:

- European Academy of Allergology and Clinical Immunology (EAACI) 

- European League Against Rheumatism (EULAR)

- Italian Society of Allergy and Clinical Immunology (SIAIC)

2014-present - Member of the:

- Italian Society of Rheumatology (SIR)


Professional Honors

2021 - MyFirst AIRC Grant

2021 - FOREUM Career Research Grant

2019 - “Cariplo – Giovani Ricercatori” Research Grant

2019 - “Best oral communication” (Italian Society of Rheumatology annual meeting)

2019 - “Best oral communication” (European League Against Rheumatism annual meeting) 

2018 - “Best oral communication” (Italian Society of Rheumatology annual meeting)

2016  - “Progressi in Medicina e Biologia” award (Collegio Ghislieri di Pavia)

2016 - “American College of Rheumatology (ACR) and the European League Against  Rheumatism (EULAR) collaborative Research Grant

2015 - “TRIDEO” (TRansforming IDEas in Oncological research) AIRC Research Grant.

2014 - “FIRA Onlus”(Fondazione Italiana Ricerca sull’Artrite) Research Grant

(Update july 2022)


Selected publications

1. Della-Torre E, et al. IL-1 and IL-6 inhibition affects the neutralising activity of anti-SARS-CoV-2 antibodies in patients with COVID-19. Lancet Rheumatol. 2021 Dec;3(12):e829-e831

2. Della-Torre E, et al. Respiratory Impairment Predicts Response to IL-1 and IL-6 Blockade in COVID-19 Patients With Severe Pneumonia and Hyper-Inflammation. Front Immunol. 2021 Apr 29;12:675678

3. Della-Torre E, et al. B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease. J Allergy Clin Immunol. 2020 Mar;145(3):968-981.e14.

4. Lanzillotta M, Mancuso G, Della-Torre E. Advances in the diagnosis and management of IgG4 related disease. BMJ. 2020 Jun 16;369:m1067.

5. Della-Torre E, et al. Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study. Ann Rheum Dis. 2020 Oct;79(10):1277-1285.

6. Minici C, Rigamonti E, Lanzillotta M, Monno A, Rovati L, Maehara T, Falconi M, Pillai S, Manfredi AA, Della-Torre E. B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma. Oncoimmunology. 2020 Jul 16;9(1):1794359.

7. Della-Torre E, et al. A CD8- Subset of CD4+ SLAMF7+ Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment. Arthritis Rheumatol. 2018 Mar 2. doi: 10.1002/art.40469.

8. Della-Torre E, et al. B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease. Ann Rheum Dis. 2015 Dec;74(12):2236-43.

(Update july 2022)

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