Giordano Leone Professore AssociatoMedicineMED/31





Degree in Medicine and Surgery on 20/07/1995 at the University of Pavia with a score of 110/110

Qualified to practice the Medical Profession at the University of Pavia in the first session 1996 (May 1996)

Specialization in Otolaryngology awarded on 11/13/2000 at the University of Turin, scoring seventy points out of seventy cum laude (70 cum laude/70)

Second Level Master in Aesthetic Surgery awarded at the University of Milan, Academic Year 2011/2012


From 2005 to 2022 Adjunct Professor at the Vita-Salute San Raffaele University, Faculty of Medicine and Surgery- School of Specialization in Otolaryngology 

Since  01-11-2022    University Associate Professor  for the S.S.D.

MED/31 – Otolaryngology at the Faculty of Medicine and Surgery ,   Vita Salute San Raffaele University, Milan

Activity tutor and path tutor for postgraduates of the Specialization School of Otolaryngology

Co-Supervisor in the drafting and implementation of numerous research projects for degree theses in Medicine and Surgery and Specialization thesis  in Otolaryngology 


Since 04/02/2002  full-time Medical Ent Doctor and later Senior Ent Medical Doctor  at the Otolaryngology Operating Unit, IRCCS San Raffaele Institute, Milan

Over 5,000 ENT surgical procedures performed as main surgeon

He focuses his interest on major oncological surgery of the head and neck and reconstructive surgery with local flaps, pedunculated and revascularized with microsurgical techniques

Coordinator of the Disease Unit Head and Neck Cancer ,   San Raffaele Hospital


Author / Co-author of

71  scientific papers including publications in national and international scientific journals, 8 book chapters 

Principal Investigator PI of the study entitled: “ Neurophysiological Intraoperative Monitoring During Neck Dissection.NIMED” Prospective Randomized Monocentric Study Unit:

Otolaryngology , Clinical Department : Head and Neck Department, Research Division: Neuroscience  Scientific Institute San raffaele Hospital

 Main Outcome: Impact of intraoperative monitoring of the spinal accessory nerve to reduce its  damage  during neck dissection

Principal Investigator PI of the study entitled:” Use of indocyanine green angiography in reconstructive surgery of head and neck”  prot HeadNeckSurg ,  a prospective observational study compared with an historical cohort

Co-Pi in the study entitled :” Economic and health  implications of two different follow-up strategies in  advanced head and neck cancer effectively treated INT 48/14 protocol of Fondazione IRCCS National Cancer Institute

-Registered since 1997 in the SIO “ Italian Society of Otorhinolarynology and Head and Neck Surgery”

-Founding Partner   ‘A.I.O.C.C. “ Italian Association of Head and Neck Oncology” and registered since 2010

-Member of the  European Head and Neck Society

 Editorial Board  Member of   “Global Journal of Otolaryngology” 

 Editorial Board Member  and Associate Editor of  "Otolaryngology Open Access Journal" (OOAJ)

Reviewer of  scientific journals  including  Laryngoscope, Acta Otorhinolaryngologica Italica 


-Winner of the “Best Dissection Award” XX Course  Andreas Vesalius, Intensive course of dissective Anatomy and Operative Techniques; Modern Fundamental Techniques of Rhinological Surgery (Endoscopic , Aesthetic Reconstructive); Brussels, November 18-22 , 2003 di Anatomia Dissettiva e Tecniche Operatorie; Moderne tecniche Fondamentali di Chirurgia Rinologica (Endoscopica, Estetica, Ricostruttiva); Bruxelles , 18-22 novembre 2003

-Winner of the AOOI Award named after prof. Francesco Marzetti during the 108th Sio Congress, Rome 25-28 May 2022

Award for the best video entitled:” The use of fluorescence with indocyanine gree in head and neck  oncological surgery : advantages and possible fiels of application “

-Prix Poster Cancerologie,115 Congrès de la Sociètè Française d’ORL et de chirurgie de la Face et du Cou

“Laryngectomie subtotale avec trachèo-hyoidopexie: expèrience multicentrique”

Bussi M., Rizzotto G., Succo G., Recanati P., Pazzaia T., Crosetti E., Giordano L.

(11 nov 20022)


Google Schoolar:



Galli A.,  Giordano L.,  Biafora M., Tulli M., Di Santo D., Bussi M.

Voice prosthesis rehabilitation after total laryngectomy: are satisfaction and quality of life maintained over time?

Acta Otorhinolaryngologica Italica 2019; 39:162-168

DOI 10.14639/0392-100X-2227

Tulli M., Re M., Bondi S., Ferrante L.,Dajko M.,  Giordano L.,  Gioacchini F.M.,Galli A.,  Bussi M.

The Prognostic Value of Anterior Commissure Involvementin T1 Glottic Cancer: A Systematic Review and Meta-Analysis

Laryngoscope, 2019 ; 00:1-9

Galli A., Tulli M., Giordano L., Biafora M., Di Santo D., Bondi S., Piccioni L. O., Bussi M.

Fine needle aspiration cytology for parotid neoplasms: risk of malignancy through inconclusive results and lower grade tumors

European Archives of Oto-Rhino-Laryngology and Head & Neck 2019;  ISSN 0937-4477

Doi 10.1007/s00405-019-05733-w

Ferraro M., Battista R.A.,  Giordano L., Bussi M.

Tailored Nasal Reconstruction after Dog-bite  Injuri in a Young Woman

Indian J Plast Surg  2020

 DOI  10.1055/s-0040-1709811

Galli A., Colombo M., Carrara g., Lira Luce F., Paesano P.L., Giordano L., Bondi S., Tulli M., Mirabile A., De Cobelli F., Bussi M.

Low skeletal  muscle mass as predictor of postoperative complications and decreased overall survival in locally advanced head and neck squamous cell carcinoma: the role of ultrasound of rectus femoris muscle

European Archives of Oto-Rhino-Laryngology and Head & Neck 2020; DOI 10.1007/s00405-020-06123-3

Mirabile A., Biafora M., Giordano L., Arrigoni G., Cangi M. G., dell’Oca I., Lira Luce F.,  Di Santo D., Galli A., Tulli M., Mellone R.,  Valsecchi D., Gregorc V., Bussi M.

Uncommon Site of Metastasi and Prolonged  Survival in Patients with Anaplastic Thyroid Carcinoma : A systematic Review of the Literature

Cancers 2020, 12, 2585;


Battista R.A., Giordano L., Giordano Resti A., Bordato A., Trimarchi M., Familiari M., Ferraro M., Bandello F.M., Bussi M.

Combination of Mustardè cheek advancement flap and paramedian  forehead flap as  a reconstructive option in orbital exenteration

European Journal of Ophthalmology 2020, 1-6

DOI: 10.1177/1120672120976550

Lombardi D., Tomasoni M., Paderno A., Mattavelli D., Ferrari M., Battocchio S., Missale F., Mazzola F., Peretti G., Mocellin D., Borsetto D., Fussey J.M., Nankivell P., Skalidi N., Bussi M., Giordano L.,Galli A., Arrigoni G., Raffetti E., Pracy P., Vander Poorten V., Nicolai P.

The impact of nodal status in major salivary gland carcinoma: A multicenter experience and proposal of a novel N-classification

Oral Oncology Volume 112 2021, 105076

Trimarchi M., Vinciguerra A., Giordano Resti A., Giordano L.,

 Bussi M.

Multidisciplinary approach  to lacrimal system diseases

Acta Otorhinolaryngologica Italica 2021; 4(Suppl.1)

doi: 10.14639/0392-100X-suppl.1-41-2021-XX

Galli A., Tulli M., Vella A., Familiari M.,   Giordano L., Bondi S., Di Santo D.,  Biafora M., M.,  Bussi M.

The importance of patient perspective in function-sparing parotid surgery for benign neoplasms: clinical reappraisal

Acta Otorhinolaryngologica Italica 2021;  41:1-10

doi: 10.14639/0392-100X-N1463

Capriotti V., Mattioli F., Guida F., Marcuzzo A. V., Lo Manto A., Martone A., Molinari G., Fabbris C., Menegaldo A., Calvanese L., Latini G., Cingolani C., Gradoni P., Boscolo Nata F.,    Giordano L., Indelicato P., Pilolli F., Mevio N., Roncoroni L., Papi S., Meschiari M., Tominz R., D’Ascanio L., Dragonetti A. G., Torelli L., Trenti L., Spinato G., Boscolo-Rizzo P., Bussi M., Cossarizza A., Presutti L., Tirelli G.

COVID-19  in the tonsillectomized population

Acta Otorhinolaryngologica Italica 2021;  41:197-205

doi: 10.14639/0392-100X-N1436

Galli A., Bondi S., Canevari C., Tulli M., Giordano L., Di Santo D.,  Gianoli L.,  Bussi M.

High-risk early-stage oral tongue squamous cell carcinoma, when free margins are not enough: Critical review

Head & Neck 2021;  

doi: 10.1002/hed.26718

Bramati C., Melegatti M.N. , Lalla F., Giordano L.

Management of two rare cases  of dermatofibrosarcoma protuberans arising in the parotid region

BMJ case report 2021;14:e243837

 doi:10.1136/bcr-2021- 24383   

Mattioli F. , Fermi M., Martone A., Ghirelli M.,    Giordano L., Di Santo D., Bussi M.,  Presutti L.

Supraclavicular artery fascial flap (SAFF): A new tool in salvage total laryngectomy

Acta Otorhinolaryngologica Italica 2021;  41:1-7

ISSN 0392-100x

doi: 10.14639/0392-100X-N1152

Gagliardi F.,    Giordano L

Temporal flaps in  head and neck reconstructive surgery: a systematic review on surgical techniques

Central European Neurosurgery 2021.  

Gagliardi F.,    Giordano L., Bussi M., Mortini P.

Local Pterional advancement  flap: a minimally-invasive option to reconstruct spheno-temporal extracranial soft tissues dehiscences in fragile patients

Journal of Craniofacial Surgery 2021;

doi: 10.1097/SCS.0000000000008051



Familiari M., Di Santo D., Galli A., Dané G.,  Giordano L.,,Mellone R.,    Bussi M.

 Spontaneous extracapsular parathyroid adenoma hemorrhage: when surgery is required?

Endocrine 2021;

Fussey J.,, Tomasoni M., Tirelli G., Giordano L., Galli A.,Colangeli R., Cazzador D., Tofanelli M., da Mosto M.C., Bianchini C., Pelucchi S., Ubavasiri K., Elsayed M., Long P., Raratziotis A., Hajiioanou J., Piazza C., Deganello A., Lombardi D.,  Nicolai P., Pracy P., Nankivell P., Borsetto D., Boscolo-Rizzo P.

Prognostic indicators in clinically node-negative malignant primary salivary tumours of the parotid: a multicentre experience  

Oral Oncology  123 (2021) 105577

DOI: 10.1016/j.oraloncology.2021.105577

Galli A., Colombo M., Prizio C.,Carrara G., Lira Luce F., Paesano P.L., Della Vecchia G., Giordano L., Bondi S., Tulli M., Di Santo D., Mirabile A., De Cobelli F., Bussi M.

Skeletal  muscle depletion and major posoperative complicationsmass as predictor of postoperative complications in locally advanced head and neck cancer: a comparison between  ultrasound of rectus femoris muscle and neck cross-sectional imaging

Cancers 2022,14,347

Familiari M., Ferrario F., Giordano L., Di Santo D., Indelicato P., Battista R.A., Bussi M.

 Management of obstructive pathology of the salivary glands in elderly patients: a preliminary study

The Journal  of Laryngology & Otology 2021

 DOI: 10.1017/S0022215121003881

Bramati C., Biafora M., Galli A., Giordano L.

Use of  platelet-rich plasma in irradiated patients to treat and prevent complications of head and neck surgery

BMJ case report 2022;15:e247766

DOI: 10.1136/bcr-2021-247766

Giordano L., Galli A., Familiari M., Canta D., Irem Ayhan., Biafora M., Battista R.A.,  Bussi M.

Head and neck pedicled flap autonomization using a new high-resolution indocyanine green fluorescence video-angiography device  

Head & Neck 2022; 1-4  

DOI: 10.1002/hed.27051

Giordano L.,  Familiari M., Galli A., Bright H., Bussi M.

Trimming of Facial  Artery Miomucosal Flap (FAMM) using Indocyanine Green Fluorescence Video-Angiography: Operative Nuances  

Ann Surg Oncol 2022;

Galli A., Giordano L.

ASO  Author Reflections: The Role of Indocyanine Green Fluorescence Video Angiography in Enhancing the Accuracy of Head and Neck Surgical Oncology  

Ann Surg Oncol 2022;

Barbieri D., Melegatti M.N., Vinciguerra A., Indelicato P., Giordano L., Bondi S., Biafora M., Trimarchi M., Bussi M.

The use of near-infrared autofluorescence during total laryngectomy with hemi-or total thyroidectomy    

European Archives of Oto-Rhino-Laryngology 2022;

DOI: 10.1007/s00405-022-07584-4

Barbieri D., Indelicato P., Vinciguerra A., Salerno E., Battista R.A., Di Marco F.,  Giordano L., Lira Luce F., Bondi S., Biafora M., Trimarchi M., Bussi M.

The impact of near-infrared autofluorescence on postoperative hypoparathyroidism during total thyroidectomy: a case-control study     

Endocrine 2022;

Il titolare del presente curriculum vitae, pubblicato online sul portale, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.