Anzalone Nicoletta Emanuela Professore associatoMedicineMED/37 Neuroradiologia

PROFESSIONAL ACTIVITIES

-  2017 – Present.

Associate professor of Neuroradiology, Università Vita-Salute, Scientific Institute  HS Raffaele,  Milan, Italy

- 2002 - Present

Head Neuroradiology Unit of Advanced Vascular Imaging , Neuroradiology Dept, Scientific Institute  HS Raffaele Milan

1997 –  2002 Senior staff Neuroradiology Dept, Scientific Institute  HS Raffaele,Milan  

1989  - 1997  Staff Neuroradiologist, Neuroradiology  Dept, Scientific Institute  HS Raffaele, Milan

TEACHING ACTIVITIES

- 2017– Present.

Associate  professor of Neuroradiology, Vita e salute University, Scientific Institute  HS Raffaele, Milan

  1994 – 2004

Professor of Neuroradiology  at the Università degli Studi Milan, Neurology specialty course

MEDICAL DEGREE

April 5th 1985

School of Medicine (Università degli Studi, Milan. Italy).(Cum laude)

GRADUATE TRAINING

Specialty: Neurology(1985-1989) University of Milan. (Cum laude)

Speciality: Radiology (1989-1993) University of Milan. (Cum laude)

PUBLISHED PAPERS

92 articles reported on Scopus, h-index 25

13 book chapters mainly focused on cerebrovascular diseases

AWARDS

European Society of Neuroradiology Scientific Award 1992

AFFILIATED SOCIETIES AND MEMBERSHIP

Italian Association of Neuroradiology (executive member 2017-present)

Secretary  of Italian Association of Neuroradiology (2017-present)

Italian Society of Radiology (executive member 2010)

Member of ASNR vessel wall imaging  study group

Member of the European Society of Neuroradiology (2016-present)

INVITED LECTURES

A part from several italian lectures at national congresses of Neurology,Neurosurgery ,Radiology and neuroradiology societies, invited speaker at :

• European Congress of Radioloy 1999, ‘05, ‘06, ‘08, ‘09, ’12, ’15,’20,’21.
• European Society of Neuroradiology 2005, ‘09, ’15, ’18,’19,’20
• Cardiovascular and Interventional Radiological Society of Europe 2006
• European Course of Neuroradiology 2009,’11,’17
• Korean Society of Magnetic Resonance in Medicine 2012
• Congreso Internacional, V reunion anual de integracion en imagenologia (Mexico City) 2009, ‘14
• Asian Oceanian Society of Radiology (Taipei) 2010
• State of the art MRI European Symposium 2012
• Update in Clinical Neuro MRI 2014
• Satellite Meeting RSNA 2009, ‘14
• Invited Professor a Mayo Clinic , Rochester 2018
• American Society of Functional Neuroradiology 2020

ORGANIZATIONAL SKILLS

Organizer of several courses and meetings of the Neuroradiological and Radiological Italian societies

Coordinator of multicentric studies on brain tumour imaging. In particular PI of national multicentric studies to test new gadolinium contrast media in brain tumors and PI of a multicentric study to test brain MR Perfusion techniques

at 3T in brain tumors with the aim to stundardize the acquisition . This last study has been published in Radiology in 2018 .

As a neuroradiologist expert in advanced techniques in brain tumor imaging  cooperated in clinical trials on brain primary lymphomas designing a protocol to study the effect of new therapies on tumor vascularization to promote chemotherapic agents target effect. This last study has been published on Blood in 2019.

GRANTS (as PI)

PI of phase I, II and III studies on MR contrast media in vascular and tumoral pathology of the central nervous system

PROFESSIONAL COMPETENCE

Main field of interest: Neurovascular imaging ( papers and commentaries on international journals on the application of MRA in extra-intracranial arteries ; definition of MRA protocols in the study of cerebral aneurysms);

Paramagnetic contrast media (international cooperations with major Pharmaceutical industries , member and coordinator of advisory boards, coordination of multicentre studies on validation and comparison of gadolinium contrast media, editorial publication on AJNR);

MR studies in tumour (member of dedicated international advisory boards with publication of specific reviews on the topic of perfusion; coordination of a multicenter study on validation of different PWI acquisition techniques in brain gliomas)

Reviewer for European Journal of Radiology, European Radiology, Journal of Neurology, Neurological Sciences, American Journal of Neuroradiology, Neuroradiology

Associate Editor of Frontiers Radiology

Pubblicazioni 2016-2018

 

1. Santarosa C, Castellano A, Conte GM, Cadioli M, Iadanza A, Terreni MR, Franzin A, Bello L, Caulo M, Falini A, Anzalone N. (2016). Dynamic contrast enhanced and dynamic susceptibility contrast perfusion MR imaging for glioma grading: preliminary comparison of vessel compartment and permeability parameters using hotspots and histogram analysis. Eur J Radiol ,85(6): 1147-56

 

2. Moroni, F., Ammirati, E., Magnoni, M., D’Ascenzo, F., Anselmino, M., Anzalone, N., Rocca, M. A., Falini, A., Filippi, M., & Camici, P. G. (2016). Carotid atherosclerosis, silent ischemic brain damage and brain atrophy: A systematic review and meta-analysis. Int J Cardiol, 223, 681-687

 

 

3. Conte GM, Castellano A, Altabella L, Iadanza A, Cadioli M, Falini A, Anzalone N.(2017). Reproducibility of dynamic contrast enhanced MRI and dynamic susceptibility contrast MRI in the study of brain gliomas: a comparison of data obtained using different commercial software. Radiol Med ,122(4): 294-302

 

4. Ammirati E, Moroni F, Magnoni M, Rocca MA, Messina R, Anzalone N, De Filippis C, Scotti I, Besana F, Spagnolo P, Rimoldi OE, Chiesa R, Falini A, Filippi M, Camici PG. (2017). Relation between characteristics of carotid atherosclerotic plaques and brain white matter hyperintensities in asymptomatic patients. Sci Rep,7 (1)

 

5. Endrikat J, Anzalone N. (2017). Gadobutrol in India- A comprhensive review of safety and efficacy. Magn Reson Insights, 10

 

6. Mapelli P, Zerbetto F, Incerti E, Conte GM, Bettinardi V, Fallanca F, Anzalone N, Di Muzio N, Gianolli L, Picchio M. (2017). 18F-FAZA PET/CT Hypoxia Imaging of High Grade Glioma before and after radiotherapy. Clin Nucl Med 42(12): 525-526

 

7. Anzalone N, Castellano A, Cadioli M, Conte GM, Cuccarini V, Bizzi A, Grimaldi M, Costa A, Grillea G, Vitali P, Aquino D, Terreni MR, Torri V, Erickson BJ, Caulo M (2018). Brain gliomas: Multicenter standardized assessment of Dynamic contrast enhanced and dynamic susceptibility contrast MR images. Radiology 287 (3): 933-943

 

8. Schwarz G, Anzalone N, Baldoli C, Impellizzeri M, Minicucci F, Comi G, Colombo B. (2018). Pediatric sporadic hemiplegic migrain( ATP1A2 gene): a case report and brief literature review. Neurol Sci 39(supp1): 69-71

 

9. Palesi F, De Rinaldis A, Vitali P, Castellazzi G, Casiraghi L, Germani G, Bernini S, Anzalone N, Ramusino MC, Denaro FM, Sinforiani E, Costa A, Magenes G, D’Angelo E, Gandini Wheeler-Kingshott CAM, Micieli G. (2018). Specific patterns of white matter alterations help distinguishing Alzheimer’s and vascular dementia. Front Neurosci 12:274

 

10. Altabella L, Broggi S, Mangili P, Conte GM, Pieri V, Iadanza A, Del Vecchio A, Anzalone N, di Muzio N, Calandrino R, Falini A, Castellano A. (2018). Integration of diffusion magnetic resonance tractography into tomotherapy radiation treatment planning for high grade gliomas. Phys Med 55:127-134