Lamanna Jacopo Ricercatore tempo determinato tipo bPsychologyBIO/09 - Fisiologia

After graduating in Biomedical Engineering (MSc) at Politecnico di Milano in 2009, he obtained the PhD in Bioengineering at the same institution in 2013, with a thesis on the non-linear dynamics of synaptic transmission. Then he worked as a Post-doc Research Fellow in the Neurobiology of Learning Unit, Division of Neuroscience, San Raffaele Scientific Institute, where he applied in vitro and in vivo electrophysiology to study synaptic transmission and plasticity. He worked as Contract Professor of Physiology at the Faculty of Medicine and Surgery of Vita-Salute San Raffaele University. From 2016 he has been working as Assistant Professor of Physiology at the Faculty of Psychology of Vita-Salute San Raffaele University where he has been Professor and Coordinator of the course “Neurobiology of Learning and Memory” and “Elements of Anatomy and Physiology of the Nervous System”. In 2017 he received the NARSAD Young Investigator Grant (Brain and Behavior Research Foundation, New York, USA).

Main research interests

 

• Physiological bases of synaptic transmission and plasticity.
• New techniques for measuring neuronal communication in vivo.
• Role of synaptic plasticity in animal behavior and mental disorders.

(Update sep. 2022)

Selected Publications:

Lamanna, J.*, Isotti, F., Ferro, M., Racchetti, G., Anchora, L., Rucco, D., & Malgaroli, A.* (2021). Facilitation of dopamine‐dependent long‐term potentiation in the medial prefrontal cortex of male rats follows the behavioral effects of stress. J. Neurosci. Res.. 2021; 99: 662– 678. https://doi.org/10.1002/jnr.24732 (*co-corresponing authors)

Previdi A, Piazzoni C, Borghi F, Schulte C, Lorenzelli L, Giacomozzi F, Bucciarelli A, Malgaroli A, Lamanna J, Moro A, Racchetti G, Podestà A, Lenardi C, Milani P. Micropatterning of Substrates for the Culture of Cell Networks by Stencil-Assisted Additive Nanofabrication. Micromachines. 2021; 12(1):94. https://doi.org/10.3390/mi12010094

Schulte, C.*, Lamanna, J.*, Moro, A. S., Piazzoni, C., Borghi, F., Chighizola, M., Ortoleva, S., Racchetti, G., Lenardi, C., Podestà, A., Malgaroli, A., & Milani, P. (2018). Neuronal Cells Confinement by Micropatterned Cluster-Assembled Dots with Mechanotransductive Nanotopography. ACS Biomaterials Science and Engineering, 4(12), 4062–4075. https://doi.org/10.1021/acsbiomaterials.8b00916 (*co-first authors)

Lamanna, J., Sulpizio, S., Ferro, M., Martoni, R., Abutalebi, J., & Malgaroli, A. (2019). Behavioral assessment of activity-based-anorexia: how cognition can become the drive wheel. Physiology and Behavior, 202(November 2018), 1–7. https://doi.org/10.1016/j.physbeh.2019.01.016

Criscuolo, E., Spadini, S., Lamanna, J., Ferro, M., & Burioni, R. (2017). Bacteriophages and Their Immunological Applications against Infectious Threats. Journal of Immunology Research, 2017. https://doi.org/10.1155/2017/3780697

Ferro, M.*, Lamanna, J.*, Ripamonti, M., Racchetti, G., Arena, A., Spadini, S., Montesano, G., Cortese, R., Zimarino, V., & Malgaroli, A. (2017). Functional mapping of brain synapses by the enriching activity-marker SynaptoZip. Nature Communications, 8(1), 1229. https://doi.org/10.1038/s41467-017-01335-4 (*equal contribution)

Schulte, C., Ripamonti, M., Maffioli, E., Cappelluti, M., Nonnis, S., Puricelli, L., Lamanna, J., Piazzoni, C., Podestà, A., Lenardi, C., Tedeschi, G., Malgaroli, A., & Milani, P. (2016). Scale invariant disordered nanotopography promotes hippocampal neuron development and maturation with involvement of mechanotransductive pathways. Frontiers in Cellular Neuroscience, 10, 267. https://doi.org/10.3389/fncel.2016.00267

Arena, A., Lamanna, J., Gemma, M., Ripamonti, M., Ravasio, G., Zimarino, V., Vitis, A., Beretta, L., & Malgaroli, A. (2017). Linear transformation of the encoding mechanism for light intensity underlies the paradoxical enhancement of cortical visual responses by sevoflurane. The Journal of Physiology. 2017 Jan 1;595(1):321-339. https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP272215

Lamanna, J., Signorini, M. G., Cerutti, S., & Malgaroli, A. (2015). A pre-docking source for the power-law behavior of spontaneous quantal release: application to the analysis of LTP. Frontiers in Cellular Neuroscience, 9(44). https://doi.org/10.3389/fncel.2015.00044

Montesano, G., Belfiore, M., Ripamonti, M., Arena, A., Lamanna, J., Ferro, M., Zimarino, V., Ambrosi, A., & Malgaroli, A. (2015). Effects of the Concomitant Activation of ON and OFF Retinal Ganglion Cells on the Visual Thalamus: Evidence for an Enhanced Recruitment of GABAergic Cells. Frontiers in Neural Circuits, 9(November), 1–19. https://doi.org/10.3389/fncir.2015.00077

Treccani, G., Musazzi, L., Perego, C., Milanese, M., Nava, N., Bonifacino, T., Lamanna, J., Malgaroli, A., Drago, F., Racagni, G., & others. (2014). Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through non-genomic action of corticosterone. Molecular Psychiatry, 19(4), 401.

Treccani, G., Musazzi, L., Perego, C., Milanese, M., Nava, N., Bonifacino, T., Lamanna, J., Malgaroli, A., Drago, F., Racagni, G., Nyengaard, J. R., Wegener, G., Bonanno, G., & Popoli, M. (2014). Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex. Molecular Psychiatry, 19(4), 433–443. https://doi.org/10.1038/mp.2014.5

Lamanna, J., Malgaroli, A., Cerutti, S., & Signorini, M. G. (2012). Detection of fractal behavior in temporal series of synaptic quantal release events: a feasibility study. Computational Intelligence and Neuroscience, 2012, 704673. https://doi.org/10.1155/2012/704673

Lamanna, J., Esposti, F., Malgaroli, A., & Signorini, M. G. (2011). Fractal behavior of spontaneous neurotransmitter release: from single-synapse to whole-cell recordings. Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2011, 3346–3349. https://doi.org/10.1109/IEMBS.2011.6090907

Lamanna, J., Esposti, F., & Signorini, M. G. (2010). Study of neuronal networks development from in-vitro recordings: A Granger causality based approach. Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2010, 4842–4845. https://doi.org/10.1109/IEMBS.2010.5628017

Esposti, F., Signorini, M. G., Lamanna, J., Gullo, F., & Wanke, E. (2007). How do TTX and AP5 affect the post-recovery neuronal network activity synchronization? Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2007, 3012–3015. https://doi.org/10.1109/IEMBS.2007.4352963

(Update sept. 2022)