Piemonti Lorenzo Professore associatoMedicineMED/13 – Endocrinologia
Lorenzo Piemonti, MD, born in Carate Brianza, graduated with Summa cum Laude at the University of Milan in 1994, and specialized with Summa Cum Laude in Endocrinology and Metabolic Diseases and in Micro and Experimental surgery at the University of Milan in 2000 and 2004, respectively. At the San Raffaele Scientific Institute (Milan, Italy), he serves as Director of Diabetes Research Institute (https://research.hsr.it/en/institutes/diabetes-research-institute.html) and Director of Human Islet Transplantation Program He also serves as Chief of the Beta Cell Biology Unit (https://research.hsr.it/en/institutes/diabetes-research-institute/beta-cell-biology.html), and Director of Human Islet Processing Facility, and coordinator of European Consortium for Islet Transplantation that has been providing Human beta Cell Products for research and clinical applications at OSR, in Italy and across state barriers in Europe since 2000. He also serve as Professor in Endocrinology at University “Vita Salute San Raffaele” of Milan and as Visiting Professor at Vrije Universiteit of Brussel. His area of expertise is mainly focused on diabetes and pancreatology. In particular, he has large experience about diabetes therapy and pathophysiology, regenerative medicine and pancreatic cancer. In addition, his research interests include beta cell replacement, immune tolerance induction strategies, dendritic cell biology, and stem cells. He currently serves as section Editor of Cell Transplantation-the Regenerative Medicine Journal and as associated editor of Transplant International, as member of editorial board of Acta Dibetologia, as treasurer of the International Pancreas and Islet Transplantation Association (2019-2023, IPITA) of The Transplantation Society (TTS), as member of the National Committee for Food Safety (2018-2021, Italian Ministry of Health), as member of the steering committee of The European Pancreas and Islet Transplant Registry (EPITR 2020-2025), as member of the National Board and scientific coordinator of the Italian Society of Diabetes (SID, 2020-2024) and previously (2011-2017) as member of the European Pancreas and Islet Transplantation Association (EPITA) committee of European Society for Organ Transplantation (ESOT) and Councilor of IPITA (2015-2019).
Publication activity (March 2021): Lorenzo Piemonti authored a total of 235 original articles published in peer-reviewed journals surveyed in PubMed. h-index (24/03/2021): 52 Web of Science; 55 Scopus; 63 Google Scholar. Considering the period 2015-2020 Lorenzo Piemonti authored a total of 106 original articles published in peer-reviewed journals for an impact factor of 585.331 (mean impact factor: 5.522)
Selected publications (2020-2021)
Piemonti L, Sordi V, Pellegrini S, Scotti GM, Scavini M, Sioli V, Gianelli Castiglione A, Cardillo M. Circulating CXCL10 and IL-6 in solid organ donors after brain death predict graft outcomes. Sci Rep. 2021 Mar 23;11(1):6624. doi: 10.1038/s41598-021-86085-6. PMID: 33758270.
Dispinseri S, Lampasona V, Secchi M, Cara A, Bazzigaluppi E, Negri D, Brigatti C, Pirillo MF, Marzinotto I, Borghi M, Rovere-Querini P, Tresoldi C, Ciceri F, Scavini M, Scarlatti G, Piemonti L. Robust neutralizing antibodies to SARS-CoV-2 develop and persist in subjects with diabetes and COVID-19 pneumonia. J Clin Endocrinol Metab. 2021 Jan 29:dgab055. doi: 10.1210/clinem/dgab055. Epub ahead of print. PMID: 33513242
Pellegrini S, Pipitone GB, Cospito A, Manenti F, Poggi G, Lombardo MT, Nano R, Martino G, Ferrari M, Carrera P, Sordi V, Piemonti L. Generation of β cells from iPSC of a MODY8 patient with a novel mutation in the carboxyl ester lipase (CEL) gene. J Clin Endocrinol Metab. 2021 Jan 8:dgaa986. doi: 10.1210/clinem/dgaa986. Epub ahead of print. PMID: 33417713.
Bolla AM, Gandolfi A, Borgonovo E, Laurenzi A, Caretto A, Molinari C, Catalano RS, Bianconi E, Monti P, Sordi V, Pellegrini S, Lampasona V, Costa S, Scavini M, Bosi E, Piemonti L. Rapamycin Plus Vildagliptin to Recover β-Cell Function in Long-Standing Type 1 Diabetes: A Double-Blind, Randomized Trial. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e507-e519. doi: 10.1210/clinem/dgaa791. PMID: 33124663.
Lampasona V, Secchi M, Scavini M, Bazzigaluppi E, Brigatti C, Marzinotto I, Davalli A, Caretto A, Laurenzi A, Martinenghi S, Molinari C, Vitali G, Di Filippo L, Mercalli A, Melzi R, Tresoldi C, Rovere-Querini P, Landoni G, Ciceri F, Bosi E, Piemonti L. Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study. Diabetologia. 2020 Dec;63(12):2548-2558. doi: 10.1007/s00125-020-05284-4. Epub 2020 Oct 8. PMID: 33029657; PMCID: PMC7541098.
Secchi M, Bazzigaluppi E, Brigatti C, Marzinotto I, Tresoldi C, Rovere-Querini P, Poli A, Castagna A, Scarlatti G, Zangrillo A, Ciceri F, Piemonti L§, Lampasona V§. COVID-19 survival associates with the immunoglobulin response to the SARS-CoV-2 spike receptor binding domain. J Clin Invest. 2020 Dec 1;130(12):6366-6378. doi: 10.1172/JCI142804. PMID: 32991329; PMCID: PMC7685720. (§ these authors equally contributed to the study)
Maffi P, Lundgren T, Tufveson G, Rafael E, Shaw JAM, Liew A, Saudek F, Witkowski P, Golab K, Bertuzzi F, Gustafsson B, Daffonchio L, Ruffini PA, Piemonti L; and the REP0211 Study Group; REP0211 Study Group. Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes. Diabetes Care. 2020 Apr;43(4):710-718. doi: 10.2337/dc19-1480. Epub 2020 Feb 4. PMID: 32019854
Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L. Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study. Transplantation. 2020 Jan;104(1):190-196. doi: 10.1097/TP.0000000000002777. PMID: 31365472.
Piemonti L. Islet Transplantation. 2019 Jul 21. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from http://www.ncbi.nlm.nih.gov/books/NBK278966/
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