Ospedale San Raffaele
Ospedale San Raffaele, acknowledged by the Italian Ministry of Health as Research Hospital for “molecular medicine”, integrates basic and clinical research through a translational approach, through which laboratory discoveries translate quickly into clinical therapies and where clinical needs drive basic research.
The institute aims to understand the mechanisms underlying a variety of human diseases and to identify new targets and therapeutic strategies to treat them.
Among the principal clinical areas of investigation are the central and peripheral nervous systems pathologies, cancer, and immune-mediated, infectious, genetic, cardiovascular and metabolic diseases.
Alongside the improvement of therapies, the institute seeks to develop new
technologies in genomics and imaging, which are fundamental for early diagnosis and personalized medicine. The Institute is recognized as a global authority in cell and gene therapy, and is at the forefront of research in many other fields.
The organizational structure of the OSR Research Area consists in 4 Research Divisions, 4 Research Institutes and 4 Research Centers.
To know more about the OSR Scientific Reasearch you can visit the web page: https://research.hsr.it/en/our-mission.html
Immunology, Transplantation and Infectious Diseases
The Division of Immunology, Transplantation and Infectious Diseases comprises several research units, which work both on independent projects and integrated multidisciplinary programs.
Studies on fundamental mechanisms underlying the immune cell physiology are performed and compared with the alterations characterizing pathological processes, aiming at both elucidating the molecular bases of diseases and defining new therapeutic strategies for a wide range of pathological conditions such as cancer, infections, autoimmunity, allergy and organ transplantation.
Scientists affiliated to the Division of Neuroscience work together to investigate key and hot issues in neuroscience, with emphasis on the areas of neurobiology, neuroepidemiology, neuropathology, neurophysiology, neuroimmunology, psychopathology and neuroimaging.
The focus of the Division of Experimental Oncology is to develop translational research programs and clinical research. Extensive collaborations and joint activities foster the implementation of translational research through access to a large number of patients and samples and combined resource platforms. Cancer genetics cancer microenvironment; cancer immunology and immunotherapy.
Genetics and Cell Biology
Cutting edge areas in the Division of Genetics and Cell Biology are the
physiopathology of cell stress and iron metabolism, chromatin dynamics,
genetics and epigenetics. Internationally competitive groups are working
in cell adhesion, migration and polarity. Molecular mechanism underlying
diseases (conformational diseases, cystic kidney disorders, neuromuscular
diseases, inflammation, iron-related diseases, disorders of human reproduction, osteoporosis and bone diseases) are being investigated by many groups with robust animal and cellular models and patients’ biological samples.
Istituto San Raffaele Telethon per la Terapia Genica (SR-Tiget)
Instituto di Neurologia Sperimentale (INSPE)
Instituto di Ricerca sul Diabete (DRI)
Instituto di Ricerca Urologica (URI)
The 4 Institutes include clinical and translational research units that work in collaboration with Ospedale San Raffaele physicians and patients.
For details about please visit the webpage: https://research.hsr.it/en/institutes/index.html
Experimental Imaging Center
Center for Omics Sciences (COSR)
Center of Advanced Services for In-Vivo Testing
High Field MR Center (Centro Eccellenza Risonanza Magnetica Alto Campo)
The 4 research centers provide forefront technologies and methods in the field of genetics, bioinformatics, medical imaging, IT and animal research.
For more details about their activity you can visit the webpage: