Danese Silvio Professore OrdinarioMedicinaMED/12

Silvio Danese is a Gastroenterologist and Professor of Gastroenterology at Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy, since October 2021, where he is Head Gastroenterology and Gastrointestinal Endoscopy Unit.

Before that, Prof Danese was Head of IBD Centre and ImmunoCentre at IRCCS Humanitas, Rozzano, Milan, Italy, and Professor of Gastroenterology at Humanitas University.

Silvio Danese trained in Gastroenterology at Policlinico Gemelli, Rome and graduated as a PhD, working from 2001 to 2004 in Dr. Claudio Fiocchi’s laboratory at the Case Western Reserve University, Cleveland, Ohio, USA.

 

His main research area of interest is the investigation of the fundamental mechanisms underlying IBD pathogenesis, while his daily clinical activity is related to IBD service. He is actively involved in many international clinical trials in IBD and has published more than 700 papers in several journals, including New England Journal of Medicine, Lancet, Gastroenterology, Gut, Journal of Clinical Investigation.

 

He is a member of many organizations related to the IBD field, including the European Crohn´s and Colitis Organization (ECCO), where he is Past President (2018 – 2020).

ORCID ID: https://orcid.org/0000-0001-7341-1351

EDUCATION AND TRAINING

1999 Degree in Medicine, Catholic University School of Medicine, “A. Gemelli” Hospital, Rome, Italy, 110/110 Cum Laude

1993 High School Diploma in Scientific Studies, Liceo Scientifico Galileo Galilei, Potenza, 60/60

RESIDENCY PROGRAM

2003 Residency in Gastroenterology, Residency Program in Gastroenterology, Catholic University School of Medicine, Rome, Italy, 70/70 Cum Laude

ACADEMIC CAREER

2013 Full Professor of Gastroenterology (Professore Ordinario), National Scientific Habilitation, Italy

2013 Full Professor of Internal Medicine (Professore Ordinario), National Scientific Habilitation, Italy

2004 PhD in Metabolism, Catholic University School of Medicine, Rome, Italy

2001 – 2002 Post-doctoral fellowship, Case Western Reserve University, Cleveland, Ohio, USA

2002 – 2004 Research Associate, Case Western Reserve University, Cleveland, Ohio, USA

ACADEMIC APPOINTMENTS

2021 – present Full Professor of Gastroenterology, Vita-Salute San Raffaele University, Milano, Italy

2015 – 2021 Full Professor of Gastroenterology, Humanitas University, Rozzano, Milano, Italy

2015 – 2020 Director, Residency Program of Gastroenterology, Humanitas University, Rozzano, Milano, Italy

2019 – present Faculty Member, PhD Program in MOLECULAR AND EXPERIMENTAL MEDICINE, Humanitas University, Rozzano, Milano, Italy

2007 – 2014 Teacher, School of Medicine of Università degli Studi di Milano, Milano, Italy CLINICAL

PROFESSIONAL EXPERIENCES

2021 – present Director, Gastroenterology and Gastrointestinal Endoscopy Unit Istituto Clinico San Raffaele, Milano

2016 – 2021 Director, Immunocenter, (IBD, Rheumatology, Dermatology) Istituto Clinico Humanitas, Rozzano, Milano

2008 – 2021 Head, IBD Center, Department of Gastroenterology, Istituto Clinico Humanitas, Rozzano, Milano

2006 – 2008 Staff member, Gastroenterology Unit, Department of Gastroenterology, Istituto Clinico Humanitas, Rozzano, Milano

THE LAST GRENTS
· 5 years grant from European Community on Immune mediate diseases. Work package coordinator. (400.000 Euro) (2011)

·4 years grant from NIH for the project: The lymphatic system in Inflammatory bowel disease (1.000.000 US $) (2011)

· 2 years Grant from The Broad Foundation for the project: The role of Triggered Receptor Expressed on Myeloid cell-2 (TREM-2) and intestinal flora in colon cancer development (220.000 Euro) (2012)

· 3 years Grant from AIRC for the project: The role of Triggered Receptor Expressed on Myeloid cell-2 (TREM-2) and intestinal flora in colon cancer development (360.000 Euro) (2013)

· 3 years Grant from the Italian Ministery of Health for the project: New cellular and molecular mechanisms in Colitis-Associated Colorectal Cancer: implications for innovative therapeutic approaches (450.000 Euro) (2013)

· 4 years Grant from Italian Ministery of Health (FIRB-Futuro in Ricerca) for the project: New cellular and molecular mechanisms in Colitis-Associated Colorectal Cancer: implications for innovative therapeutic approaches (448.000 Euro) (2013)

· 2 years Grant from Humanitas Research Hospital for the project: The role of TREM-2 in IBD pathogenesis: implications for novel therapeutic approaches (100.000 Euro) (2014)

· 3 years Grant from AIRC for the project: Role of TRPV-4 in the pathogenesis of Colorectal Cancer (450.000 Euro) (2017)

· 2 years Grant from the Broad Medical Research Program for the project: Resolution of IBD by promoting endogenous lipid-mediated pro-resolving pathways: a novel approach to pathogenesis and therapy (140.800 Euro) (2017)

· Coordinator of a 5 year Grant from the Horizon 2020, H2020-JTI-IMI2-2018-15 IMI, Innovative Medicines Initiative 2 for the ImmUniverse project: Better control and treatment of immune-mediated diseases by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies (15,5 millions Euro) (2020) · Coordinator of a

3 years grant from EURONANOMED III for the project: Gut-targeted RNA[1]based nanoparticles for fibrostenotic Crohn’s Disease: a novel therapeutic approach (1 million Euro) (2020)

 

(Ott-2021)

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