De Cobelli Francesco Professore ordinarioMedicinaMED/36

Biografia

Pubblicazioni

English version

Biografia

Curriculum Vitae

Studi
1991 Laurea In Medicina e Chirurgia – Università degli Studi di Milano
1995 Specializzazione in Radiologia – Università degli Studi di Milano

Esperienze professionali
1988 Research fellow in Fisiologia (Dipartimento di fisiologia e biofisica Case Western Reserve University – Cleveland; USA)
1989-1990 Studente interno in Medicina Interna (Divisione di Medicina Interna H.S Raffaele-Milano)
1991-1992 Medico Specializzando in Radiologia (Servizio di Radiologia – Ospedale San Paolo – Milano)
1992-1995 Medico Specializzando in Radiologia (Servizio di Radiologia –Istituto Scientifico H San Raffaele – Milano)
Dal 1996 Assistente Ospedaliero e successivamente Dirigente di I° livello presso il Servizio di Radiologia dell’Istituto Scientifico H San Raffaele – Milano.
Dal 2002 Coordinatore di Area di Attività scientifica e didattica del Servizio (attualmente del Dipartimento) di Radiologia dell’Istituto Scientifico H San Raffaele – Milano.
Dal 2007 Dirigente Responsabile di Unità Funzionale di Risonanza Magnetica dell’Unità Operativa (attualmente del Dipartimento) di Radiologia dell’Istituto Scientifico H San Raffaele – Milano.
Dal 2010 Professore associato per il settore scientifico-disciplinare MED 36 (Diagnostica per Immagini e Radioterapia) presso l’Università Vita – Salute San Raffaele.
Dal 2010 Capo Unità di Radiologia Clinica e Sperimentale del Centro di Imaging Sperimentale (CIS) dell’IRCCS San Raffaele.
I principali campi di attività clinica sono stati la Risonanza Magnetica, la Radiologia addominale, la Cardioradiologia e la Radiologia Interventistica.
Ha dato alle stampe n° 58 Pubblicazioni per esteso recensite nel Journal Citation Reports (JCR 2008) con Impact factor complessivo di 297.14 con IF medio di 5.12.
Inoltre, n° 12 Pubblicazioni per esteso non recensite nel JCR, 175 Pubblicazioni in forma di Abstracts e n° 18 Capitoli di libro.
Invited Speaker a più di 100 meetings nazionali e internazionali.

Pubblicazioni

Autore o coautore di 58 pubblicazioni

1. Sironi S, De Cobelli F, Scarfone G, Colombo E, Bolis G, Ferrari A, Del Maschio A. Carcinoma of the cervix: value of plain and gadolinium-enhanced MR imaging in assessing degree of invasiveness. Radiology  1993;188: 797-801. (I.F.=6.00)

2. Sironi S, De Cobelli F, Livraghi T, Villa G, Zanello A, Taccagni G, Del Maschio A. Small hepatocellular carcinoma treated with percutaneous ethanol injection: unenhanced and gadolinium-enhanced MR imaging follow-up. Radiology 1994;192: 407-412. (I.F.=6.00)

3. Scattoni V, Colombo R, Nava L, Da Pozzo L, De Cobelli F, Vanzulli A, Del Maschio A, Freschi M, Rigatti P. Imaging of renal cell carcinoma with gadolinium-enhanced magnetic resonance: radiological and pathological study. Urol Int 1995; 54:121-127. (I.F.=0.89)
4. Sironi S, De Cobelli F, Zerbi A, Balzano G, Di Carlo V, Del Maschio A. Pancreatic carcinoma: MR assessment of tumor invasion of the peripancreatic vessels. J Comput Assist Tomo 1995; 19(5): 739-744. (I.F.=1.45)
5. Scattoni V, Da Pozzo LF, Colombo R, Nava L, Rigatti P, De Cobelli F, Vanzulli A, Del Maschio A. Dynamic gadolinium-enhanced magnetic resonance imaging in staging of superficial bladder cancer. J Urol 1996;155:1594-1599. (I.F.=3.95)
6. Sironi S, De Cobelli F, Zerbi A, Angeli E, Balzano G, Taccagni G, Di Carlo V, Del Maschio A. Pancreatic adenocarcinoma: assessment of vascular invasion with high-field MR imaging and a phased-array coil. Am J Roentgenol 1996;167: 997-1001. (I.F.=2.94)
7. De Cobelli F, Mellone R, Salvioni M, Vanzulli A, Sironi S, Manunta P, Lanzani C, Bianchi G, Del Maschio A. Renal artery stenosis: value of screening with three-dimensional phase-contrast MR angiography with a phased-array multicoil. Radiology 1996;201:697-703. (I.F.=6.00)
8. Castrucci M, Sironi S, De Cobelli F, Salvioni M, Del Maschio A. Plain and gadolinium-DTPA-enhanced MR imaging of hepatocellular carcinoma treated with transarterial chemoembolization. Abdom Imaging 1996; 21: 488-494. (I.F.=1.48)
9. De Cobelli F, Vanzulli A, Sironi S, Mellone R, Angeli E, Venturini M, Garancini MP, Quartagno R, Bianchi G, Del Maschio ARenal artery stenosis: evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography. Radiology 1997;205:689-695. (I.F.=6.00)
10. Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 1999;48:1600-1606. (I.F.=8.40)
11. Sironi S, Livraghi T, Meloni F, De Cobelli F, Ferrero C, Del Maschio A. Small hepatocellular carcinoma treated with percutaneous RF ablation: MR imaging follow-up. Am J Roentgenol 1999; 173: 1225-1229. (I.F.=2.94)
12. De Cobelli F, Venturini M, Vanzulli A, Sironi S, Salvioni S, Angeli E, Scifo P, Garancini MP, Quartagno R, Bianchi G, Del Maschio A. Renal arterial stenosis: prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography. Radiology 2000; 214: 373-380. (I.F.=6.00)
13. Fiorina P, De Cobelli F, Fragasso G, Fazio R, Pozza G, Del Maschio A, Secchi A. Magnetic resonance image (MRI) of an acquired aorto-pulmonary fistula, associated with cerebral and paradoxical embolism.. Int J Cardiol 2002; 83:85-86. (I.F.=3.12)
14. Venturini M, Angeli E, Salvioni M, De Cobelli F, Trentin C, Carlucci M, Staudacher C, Del Maschio A. Hemorrhage from a right hepatic artery pseudoaneurysm: endovascular treatment with a coronary stent-graft. J Endovasc Ther 2002; 9(2): 221-224. (I.F. 2.68)
15. Picchio M, Landoni C, Messa C, Gianolli L, Matarrese M, De Cobelli F, Del Maschio A, Fazio F. Positive [11C]choline and negative [18F]FDG with positron emission tomography in recurrence of prostate cancer. Am J Roentgenol 2002; 179: 482-484. (I.F.=2.94)
16. Picchio M, Messa C, Landoni C, Gianolli L, Sironi S, Brioschi M, Matarrese M, Matei DV, De Cobelli F, Del Maschio A, Rocco F, Rigatti P, Fazio F. Value of [11C]choline-positron emission tomography for re-staging prostate cancer: a comparison with [18F]fluorodeoxyglucose-positron emission tomography. J Urol 2003;169: 1337-1340. (I.F.=3.95)
17. Orsenigo E, De Cobelli F, Salvioni M, Cristallo M, Fiorina P, Del Maschio A, Di Carlo V, Secchi A. Successful endovascular treatment for gastroduodenal artery pseudoaneurysm with an arteriovenous fistula after pancreas transplantation.Transpl Int. 2003;16: 694-696. (I.F.=3.11)
18. Picchio M, Sironi S, Messa C, Mangili G, Landoni C, Gianolli L, Zangheri B, Viganò R, Aletti G, De Marzi P, De Cobelli F, Del Maschio A, Ferrari A, Fazio F.  Advanced ovarian carcinoma: usefulness of [(18)F]FDG-PET in combination with CT for lesion detection after primary treatment.Q J Nucl Med 2003;47(2): 77-84. (I.F.=2.64)
19. Perseghin G, Lattuada G, Danna M, Sereni LP, Maffi P, De Cobelli F, Battezzati A, Secchi A, Del Maschio A, Luzi L. Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes. Am J Physiol-Endoc M 2003;285:1174-1181. (I.F.=3.86)
20. Brasca LE, Zanello A, De Gaspari A, De Cobelli F, Zerbi A, Fazio F, Del Maschio A. Intrapancreatic accessory spleen mimicking a neuroendocrine tumor: magnetic resonance findings and possible diagnostic role of different nuclear medicine tests.. eur Radiol 2004; 14 (7) : 1322-1323. (I.F:=3.65).
21. De Cobelli F, Fiorina P, Perseghin G, Magnone M, Venturini M, Zerbini G, Zanello A, Mazzolari G, Monti L, Di Carlo V, Secchi A, Del Maschio A. L-arginine-induced vasodilation of the renal vasculature is preserved in uremic type 1 diabetic patients after kidney and pancreas but not after kidney-alone transplantation. Diabetes Care 2004; 27(4): 947-954. (I.F:=7.35).
22. Perseghin G, Comola M, Scifo P, Benedini S, De Cobelli F, Lanzi R, Costantino F, Lattuada G, Battezzati A, Del Maschio A, Luzi L. Postabsorptive and insulin stimulated energy and protein metabolism in patients with myotonic dystrophy type 1.  Am J Clin Nutr 2004;80 (2): 357-364. (IF 6.74).
23. Venturini M, Angeli E, Salvioni M, De Cobelli F, Ronzoni M, Aldrighetti L, Stella M, Carlucci M, Staudacher C, Di Carlo V, Ferla G, Villa E, Del Maschio A.  Complications after percutaneous transaxillary implantation of a catheter for intraarterial chemotherapy of liver tumors: clinical relevance and management in 204 patients.. Am J Roentgenol 2004;182:1417-1428. (I.F.=2.94).
24. Venturini M, Angeli E, Maffi P, Fiorina P, Bertuzzi F, Salvioni M, De Cobelli F, Socci C, Aldrighetti L, Losio C, Di Carlo V, Secchi A, Del Maschio A. Technique, complications, and therapeutic efficacy of percutaneous transplantation of human pancreatic islet cells in type 1 diabetes: the role of US. Radiology 2005; 234: 617-624. (I.F.=6.00).
25. Lattuada G, Costantino F, Caumo A, Scifo P, Ragogna F, De Cobelli F, Del Maschio A, Luzi L, Perseghin G. Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients.. Diabetologia 2005;48: 741-747. (I.F.=6.42).
26. Perseghin G, Fiorina P, De Cobelli F, Scifo P, Esposito A, Canu T, Danna M, Gremizzi C, Secchi A, Luzi L, Del Maschio A. Cross-sectional assessment of the effect of kidney and kidney-pancreas transplantation on resting left ventricular energy metabolism in type 1 diabetic-uremic patients: a phosphorous-31 magnetic resonance spectroscopy study. J Am Coll Cardiol 2005; 46(6):1085-1092. (I.F.=11.44)
27. De Cobelli F,  Esposito A, Mellone R, Papa M, Besana R, Del Maschio A. Late enhancement of a left ventricular cardiac fibroma assessed with gadolinium-enhanced cardiovascular magnetic resonance. circulation 2005; 112:242-243. (I.F.=14.60)
28. Lang CC, Gugliotta F, Santinelli V, Mesas C, Tomita T, Vicedomini G, Augello
G, Gulletta S, Mazzone P, De Cobelli F, Del Maschio A, Pappone C. Endocardial impedance mapping during circumferential pulmonary vein ablation of atrial fibrillation differentiates between atrial and venous tissue. Hearth Rhythm 2006; 3(2):171-178. (I.F.=4.44)
29. Fragasso G, Perseghin G, De Cobelli F, Esposito A, Palloshi A, Lattuada G, Scifo P, Calori G, Del Maschio A, Margonato A. Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure. Eur Hearth J 2006;27(8):942-948. (I.F.=8.92)
30. De Cobelli F, Pieroni M, Esposito A, Belloni E, Chimenti C, Mellone R, Canu T, G. Perseghin, C. Gaudio, A. Maseri, A. Frustaci,  A. Del Maschio. Delayed gadolinium-enhanced cardiac magnetic resonance in patients with chronic myocarditis presenting with heart failure or recurrent arrhythmias. J Am Coll Cardiol 2006;47(8):1649-1654. (I.F.=11.44)
31. Pieroni M, Chimenti C, De Cobelli F, Morgante E, Del Maschio A, Gaudio C, Russo MA, Frustaci A. Fabry’s disease cardiomyopathy: echocardiographic detection of endomyocardial glycosphingolipid compartmentalization.. J Am Coll Cardiol 2006;47(8):1663-1671.  (I.F.= 11.44)
32. Perseghin G, Bonfanti R, Magni S, Lattuada G, De Cobelli F, Canu T, Esposito A, Scifo P, Ntali G, Costantino F, Bosio L, Ragogna F, Del Maschio A, Chiumello G, Luzi L. Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease.Am J Physiol-Endroc M 2006; 291(4):697-703. (I.F.=3.86)
33. Perseghin G, Lattuada G, De Cobelli F, Ntali G, Esposito A, Burska A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Serum resistin and hepatic  fat content in nondiabetic individuals. J Clin Endocr Metab 2006; 91(12):5122-5. (I.F.=6.32)
34. Schaefer FK, Schaefer PJ, Altiohann C, Bourne M, De Cobelli F, Goyen M, et al. A multicenter, site-independent, blinded study to compare the diagnostic accuracy of contrast-enhanced magnetic resonance angiography using 1.0M gadobutrol (Gadovist) to intraarterial digital subtraction angiography in body arteries. Eur J Radiol 2007;61(2):315-23. (I.F:=2.34).
35. Coli S, Magnoni M, Melisurgo G, Persico P, Doldi N, De Cobelli F, Del Maschio A, Cianflone D, Maseri A. Myocardial infarction complicating the initial phase of an ovarian stimulation protocol.Int J Cardiol 2007;31;115(1): 56-7. (I.F.=3.12)
36. Fiorina P, Perseghin G, De Cobelli F, Gremizzi C, Petrelli A, Monti L, Maffi P, Luzi L, Secchi A, Del Maschio A. Altered kidney graft high-energy phosphate metabolism in kidney-transplanted end-stage renal disease type 1 diabetic patients: a cross-sectional analysis of the effect of kidney alone and kidney-pancreas transplantation. Diabetes Care  2007;30(3):597-603. (I.F:=7.35).
37. Perseghin G, Lattuada G, De Cobelli F, Ragogna F, Ntali G, Esposito A, Belloni E, Canu T, Terruzzi I, Scifo P, Del Maschio A, Luzi L. Habitual physical activity is associated with intrahepatic fat content in humans. Diabetes Care 2007; 30(3):683-688. (I.F:=7.35).
38. Belloni E, De Cobelli F, Esposito A, Mellone R, Gentinetta F, Meloni C, Del Maschio A. Myocarditis associated with clozapine studied by cardiovascular magnetic resonance. J Cardiov Magn Reson 2007; 9:591-593. (I.F.=2.15)
39. Perseghin G, Ntali G, De Cobelli F, Lattuada G, Esposito A, Belloni E, Canu T, Costantino F, Ragogna F, Scifo P, Del Maschio A, Luzi L. Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance. Diabetes Care 2007; 30(6):1520-6. (I.F:=7.35).
40. Perseghin G, De Cobelli F, Esposito A, Lattuada G, Terruzzi I, La Torre A, Belloni E, Canu T, Scifo P, Del Maschio A, Luzi L, Alberti G. Effect of the sporting discipline on the right and left ventricular morphology and function of elite male track runners: a magnetic resonance imaging and phosphorus 31 spectroscopy study. Am Heart J 2007; 154(5):937-42. (I.F:=4.29).
41. Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation. J Clin Endocrinol Metab 2007;92(12):4883-8. (I.F:=6.32).
42. Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Ntali G, Ragogna F, Canu T, Scifo P, Del Maschio A, Luzi L. Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver. Hepatology 2008; 47(1):51-58. (I.F.=11.35)
43. Manfredi AA, Capobianco A, Esposito A, De Cobelli F, Canu T, Monno A, Raucci A, Sanvito F, Doglioni C, Nawroth PP, Bierhaus A, Bianchi ME, Rovere-Querini P, Del Maschio A. Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes. J Immunol 2008; 180(4):2270-2275. (I.F:=6.00).
44. Scotti C, Camnasio F, Rizzo N, Fontana F, De Cobelli F, Peretti GM, Fraschini G. Mammary-type myofibroblastoma of popliteal fossa. Skeletal Radiol 2008; 37(6):549-553. (I.F:=1.08).
45. Chimenti C, Hamdani N, Boontje NM, De Cobelli F, Esposito A, Bronzwear  JC, Stienen GJ, Russo MA, Paulus WJ, Frustaci A, van der Velden J. Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease.  2008;172(6):1482-90. Am J Pathol 2008;172(6):1482-90. (I.F:=5.70)
46. Belloni E, De Cobelli F, Esposito A, Mellone R, Perseghin G, Canu T, Del Maschio A. MRI of cardiomyopathy.Am J Roentgenol 2008; 191: 1702-1710 (I.F.=2.94).
47. Esposito A, De Cobelli F, Perseghin G, Pieroni M, Belloni E, Mellone R, Canu T, Gentinetta F, Scifo P, Chimenti C, Frustaci A, Luzi L, Maseri A, Del Maschio A. Impaired left ventricular energy metabolism in patients with Hypertrophic Cardiomyopathy is related to the extension of Fibrosis at Gadolinium Delayed Enhanced MR Imaging. Heart 2009;95(3):228-33. (I.F:=4.96)
48. Perseghin G, De Cobelli F, Esposito A, Belloni E, Lattuada G, Canu T, Invernizzi PL, Ragogna F, La Torre A, Scifo P, Alberti G, Del Maschio A, Luzi L. Left ventricular function and energy metabolism in middle-aged men undergoing long-lasting sustained aerobic oxidative training. Heart 2009 Apr;95(8):630-5. (I.F:=4.96)
49. Marano R, De Cobelli F, Floriani I, Becker C, Herzog C, Centonze M, Morana G, Gualdi GF, Ligabue G, Pontone G, Catalano C, Chiappino D, Midiri M, Simonetti G, Marchisio F, Olivetti L, Fattori R, Bonomo L, Del Maschio A; NIMISCAD Study Group. Italian multicenter, prospective study to evaluate the negative predictive value of 16- and 64-slice MDCT imaging in patients scheduled for coronary angiography (NIMISCAD-Non Invasive Multicenter Italian Study for Coronary Artery Disease). Eur Radiol 2009;19(5):1114-23 (I.F:=3.65)
50. Morbiducci U, Ponzini R, Rizzo G, Cadioli M, Esposito A, De Cobelli F, Del Maschio A, Montevecchi FM, Redaelli A. In Vivo Quantification of Helical Blood Flow in Human Aorta by Time-Resolved Three-Dimensional Cine Phase Contrast Magnetic Resonance Imaging. Ann Biomed Eng 2009;37(3):516-31. (I.F:=2.60)
51. De Cobelli F,  Esposito A, Belloni E, Pieroni M, Perseghin G, Chimenti C, Frustaci A, Del Maschio A. Delayed-gadolinium enhancement cardiac magnetic resonance for differentiation of Anderson-Fabry disease from symmetric hypertrophic cardiomyopathy. Am J Roentgenol 2009;192(3):97-102 (I.F. 2.94)
52. Melissano G, Bertoglio L, Civelli V, Amato AC, Coppi G, Civilini E, Calori G, De Cobelli F, Del Maschio A, Chiesa R. Demonstration of the Adamkiewicz artery by multidetector computed tomography angiography analysed with the open-source software OsiriX. Eur J Vasc Endovasc Surg. 2009;37(4):395-400. (I.F. 3.00)
53. Esposito A. De Cobelli F, Belloni E, Ravelli S, Scotti R, Sabbadini MG, Del Maschio A. Magnetic resonance imagin of a hypereosinophilic endocarditis with apical thrombotic obliteration in Churg-Strauss Syndrome complicated with acute abdominal aortic embolic occlusion. Int J Cardiol 2009 [Epub ahead of print] (I.F. 3.12)
54. Perna L, Fiorino C, Cozzarini C, Broggi S, Cattaneo GM, De Cobelli F, Mangili P, Di Muzio N, Calandrino R. Sparing the penile bulb in the radical irradiation of clinically localised prostate carcinoma: A comparison between MRI and CT prostatic apex definition in 3DCRT, Linac-IMRT and Helical Tomotherapy. Radiother Oncol 2009; 93(1):57-63. (I.F. 3.99)
55. Perseghin G, Caumo A, Lattuada G, De Cobelli F, Ntali G, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance. Diabetic Med 2009;26(9):847-54. (I.F. 3.17)
56. Mezzi G, Arcidiacono PG, Carrara S, Perri F, Petrone MC, De Cobelli F, Gusmini S, Staudacher C, Del Maschio A, Testoni PA. Endoscopic ultrasound and magnetic resonance imaging for re-staging rectal cancer after radiotherapy. World J Gastroenterol 2009; 28;15(44):5563-7. (I.F. 2.08)
57. Gregorc V, Citterio G, Vitali G, Spreafico A, Scifo P, Borri A, Donadoni G, Rossoni G, Corti A, Caligaris-Cappio F, Maschio AD, Esposito A, De Cobelli F, Dell’acqua F, Troysi A, Bruzzi P, Lambiase A, Bordignon C. Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours. Eur J Cancer 2009 Nov 7. [Epub ahead of print] (I.F. 4.47)
58. Magnoni M, Esposito A, Coli S, Scuteri L, De Cobelli F, Cianflone D,  Del Maschio A, Maseri A. Two Different Mechanisms of Myocardial Ischemia Involving 2 Separate Myocardial Segments in a Patient With Normal Coronary Angiography. Circulation 2010 Jan 5;121(1):e1-3. (I.F.=14.60)

English version

CURRICULUM VITAE

Name and Degree: Francesco De Cobelli, M.D.
Date and place of birth: May 18, 1966; Bergamo, Italy
Citizenship: Italian

EDUCATION


Diplomat, Maturitá Scientifica (General Science) 1985
Scientific high-school F. Lussana, Bergamo,

BOARD CERTIFICATION
Board certification as Phisician 1991
Università degli Studi di Milano (grade=110/110)

Board certification in Radiology 1995
Università degli Studi di Milano (grade=70/70)

CLINICAL AND RESEARCH FELLOWSHIPS
Research fellow in Phisiology 1988
(Physiology and Biophysics dept. Case Western Reserve University-Cleveland; USA)

Clinical fellow in Internal Medicine 1989-1990
(Internal Medicine Dept. H.S Raffaele-Milan)

Resident in Radiology 1991-1995
(Radiology Dept. H.S Raffaele-Milan)

PROFESSIONAL POSITIONS

Staff radiologist 1996-present
(Radiology Dept. H.S Raffaele-Milan)

Coordinator University and Research Programm 2001-present
(Radiology Dept. H.S Raffaele-Milan)

Chief Magnetic Resonance Unit 2006-present
(Radiology dept. H.S Raffaele-Milan)

Chief of Clinical and Experimental Radiology Unit 2010-present
(Experimental Imaging Centre H S Raffaele – Milan)

MEMBERSHIPS
Member, Italian Society of Radiology 1992- present
Member, European Society of Radiology 1995-present
Member, Radiological Society of North America 1999-present
Member of Scientific Board, Italian Society of Cardiac Radiology 2000-present

REFEREE OF SCIENTIFIC JOURNALS
“European Radiology”
“European Urology”
“International Journal of Cardiology”
“American Journal of Cardiology”
“European Journal of Radiology”

ACADEMIC APPOINTMENTS
Tutor of Phisics (University Vita-Salute S.Raffaele – Milan) 1999-present
Tutor of Anatomy (University Vita-Salute S.Raffaele – Milan) 1999-present.
Adjunct Professor of Radiology (University Vita-Salute S.Raffaele – Milan) 2001-present
Adjunct Professor of Urology (University Vita-Salute S.Raffaele – Milan) 2001-present
Adjunct Professor for “Adrenal disease imaging” at the Corso of Endocrinology and Metabolic Diseases – Università Vita e Salute San Raffaele, School of Medicine, 2005-06 – present.
Adjunct Professor for “Imaging of Bowel, liver, biliary tract and pancreas disease” at the Corso of Gastroenterology – Università Vita e Salute San Raffaele, School of Medicine, 2005-06 – present.
Adjunct Professor for “Imaging in Oncology” at the Corso of Oncology Vita e Salute San Raffaele, School of Medicine, 2005-06 – present.
Adjunct Professor for “Imaging in Cardiology” at the Corso of Cardiology Vita e Salute San Raffaele, School of Medicine, 2005-06 – present.
Associate Professor for Imaging and Radiotherapy at Vita e Salute San Raffaele, School of Medicine, 2010-present

Invited Speaker at more than 100 national and international meetings.

Author or Coauthor of 58 Publications with total Impact factor (JCR 2008): 297.14. 

1. Sironi S, De Cobelli F, Scarfone G, Colombo E, Bolis G, Ferrari A, Del Maschio A. Carcinoma of the cervix: value of plain and gadolinium-enhanced MR imaging in assessing degree of invasiveness. Radiology  1993;188: 797-801. (I.F.=6.00)
2. Sironi S, De Cobelli F, Livraghi T, Villa G, Zanello A, Taccagni G, Del Maschio A. Small hepatocellular carcinoma treated with percutaneous ethanol injection: unenhanced and gadolinium-enhanced MR imaging follow-up. Radiology 1994;192: 407-412. (I.F.=6.00)
3. Scattoni V, Colombo R, Nava L, Da Pozzo L, De Cobelli F, Vanzulli A, Del Maschio A, Freschi M, Rigatti P. Imaging of renal cell carcinoma with gadolinium-enhanced magnetic resonance: radiological and pathological study. Urol Int 1995; 54:121-127. (I.F.=0.89)
4. Sironi S, De Cobelli F, Zerbi A, Balzano G, Di Carlo V, Del Maschio A. Pancreatic carcinoma: MR assessment of tumor invasion of the peripancreatic vessels. J Comput Assist Tomo 1995; 19(5): 739-744. (I.F.=1.45)
5. Scattoni V, Da Pozzo LF, Colombo R, Nava L, Rigatti P, De Cobelli F, Vanzulli A, Del Maschio A. Dynamic gadolinium-enhanced magnetic resonance imaging in staging of superficial bladder cancer. J Urol 1996;155:1594-1599. (I.F.=3.95)
6. Sironi S, De Cobelli F, Zerbi A, Angeli E, Balzano G, Taccagni G, Di Carlo V, Del Maschio A. Pancreatic adenocarcinoma: assessment of vascular invasion with high-field MR imaging and a phased-array coil. Am J Roentgenol 1996;167: 997-1001. (I.F.=2.94)
7. De Cobelli F, Mellone R, Salvioni M, Vanzulli A, Sironi S, Manunta P, Lanzani C, Bianchi G, Del Maschio A. Renal artery stenosis: value of screening with three-dimensional phase-contrast MR angiography with a phased-array multicoil. Radiology 1996;201:697-703. (I.F.=6.00)
8. Castrucci M, Sironi S, De Cobelli F, Salvioni M, Del Maschio A. Plain and gadolinium-DTPA-enhanced MR imaging of hepatocellular carcinoma treated with transarterial chemoembolization. Abdom Imaging 1996; 21: 488-494. (I.F.=1.48)
9. De Cobelli F, Vanzulli A, Sironi S, Mellone R, Angeli E, Venturini M, Garancini MP, Quartagno R, Bianchi G, Del Maschio ARenal artery stenosis: evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography. Radiology 1997;205:689-695. (I.F.=6.00)
10. Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 1999;48:1600-1606. (I.F.=8.40)
11. Sironi S, Livraghi T, Meloni F, De Cobelli F, Ferrero C, Del Maschio A. Small hepatocellular carcinoma treated with percutaneous RF ablation: MR imaging follow-up. Am J Roentgenol 1999; 173: 1225-1229. (I.F.=2.94)
12. De Cobelli F, Venturini M, Vanzulli A, Sironi S, Salvioni S, Angeli E, Scifo P, Garancini MP, Quartagno R, Bianchi G, Del Maschio A. Renal arterial stenosis: prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography. Radiology 2000; 214: 373-380. (I.F.=6.00)
13. Fiorina P, De Cobelli F, Fragasso G, Fazio R, Pozza G, Del Maschio A, Secchi A. Magnetic resonance image (MRI) of an acquired aorto-pulmonary fistula, associated with cerebral and paradoxical embolism.. Int J Cardiol 2002; 83:85-86. (I.F.=3.12)
14. Venturini M, Angeli E, Salvioni M, De Cobelli F, Trentin C, Carlucci M, Staudacher C, Del Maschio A. Hemorrhage from a right hepatic artery pseudoaneurysm: endovascular treatment with a coronary stent-graft. J Endovasc Ther 2002; 9(2): 221-224. (I.F. 2.68)
15. Picchio M, Landoni C, Messa C, Gianolli L, Matarrese M, De Cobelli F, Del Maschio A, Fazio F. Positive [11C]choline and negative [18F]FDG with positron emission tomography in recurrence of prostate cancer. Am J Roentgenol 2002; 179: 482-484. (I.F.=2.94)
16. Picchio M, Messa C, Landoni C, Gianolli L, Sironi S, Brioschi M, Matarrese M, Matei DV, De Cobelli F, Del Maschio A, Rocco F, Rigatti P, Fazio F. Value of [11C]choline-positron emission tomography for re-staging prostate cancer: a comparison with [18F]fluorodeoxyglucose-positron emission tomography. J Urol 2003;169: 1337-1340. (I.F.=3.95)
17. Orsenigo E, De Cobelli F, Salvioni M, Cristallo M, Fiorina P, Del Maschio A, Di Carlo V, Secchi A. Successful endovascular treatment for gastroduodenal artery pseudoaneurysm with an arteriovenous fistula after pancreas transplantation.Transpl Int. 2003;16: 694-696. (I.F.=3.11)
18. Picchio M, Sironi S, Messa C, Mangili G, Landoni C, Gianolli L, Zangheri B, Viganò R, Aletti G, De Marzi P, De Cobelli F, Del Maschio A, Ferrari A, Fazio F.  Advanced ovarian carcinoma: usefulness of [(18)F]FDG-PET in combination with CT for lesion detection after primary treatment.Q J Nucl Med 2003;47(2): 77-84. (I.F.=2.64)
19. Perseghin G, Lattuada G, Danna M, Sereni LP, Maffi P, De Cobelli F, Battezzati A, Secchi A, Del Maschio A, Luzi L. Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes. Am J Physiol-Endoc M 2003;285:1174-1181. (I.F.=3.86)
20. Brasca LE, Zanello A, De Gaspari A, De Cobelli F, Zerbi A, Fazio F, Del Maschio A. Intrapancreatic accessory spleen mimicking a neuroendocrine tumor: magnetic resonance findings and possible diagnostic role of different nuclear medicine tests.. eur Radiol 2004; 14 (7) : 1322-1323. (I.F:=3.65).
21. De Cobelli F, Fiorina P, Perseghin G, Magnone M, Venturini M, Zerbini G, Zanello A, Mazzolari G, Monti L, Di Carlo V, Secchi A, Del Maschio A. L-arginine-induced vasodilation of the renal vasculature is preserved in uremic type 1 diabetic patients after kidney and pancreas but not after kidney-alone transplantation. Diabetes Care 2004; 27(4): 947-954. (I.F:=7.35).
22. Perseghin G, Comola M, Scifo P, Benedini S, De Cobelli F, Lanzi R, Costantino F, Lattuada G, Battezzati A, Del Maschio A, Luzi L. Postabsorptive and insulin stimulated energy and protein metabolism in patients with myotonic dystrophy type 1.  Am J Clin Nutr 2004;80 (2): 357-364. (IF 6.74).
23. Venturini M, Angeli E, Salvioni M, De Cobelli F, Ronzoni M, Aldrighetti L, Stella M, Carlucci M, Staudacher C, Di Carlo V, Ferla G, Villa E, Del Maschio A.  Complications after percutaneous transaxillary implantation of a catheter for intraarterial chemotherapy of liver tumors: clinical relevance and management in 204 patients.. Am J Roentgenol 2004;182:1417-1428. (I.F.=2.94).
24. Venturini M, Angeli E, Maffi P, Fiorina P, Bertuzzi F, Salvioni M, De Cobelli F, Socci C, Aldrighetti L, Losio C, Di Carlo V, Secchi A, Del Maschio A. Technique, complications, and therapeutic efficacy of percutaneous transplantation of human pancreatic islet cells in type 1 diabetes: the role of US. Radiology 2005; 234: 617-624. (I.F.=6.00).
25. Lattuada G, Costantino F, Caumo A, Scifo P, Ragogna F, De Cobelli F, Del Maschio A, Luzi L, Perseghin G. Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients.. Diabetologia 2005;48: 741-747. (I.F.=6.42).
26. Perseghin G, Fiorina P, De Cobelli F, Scifo P, Esposito A, Canu T, Danna M, Gremizzi C, Secchi A, Luzi L, Del Maschio A. Cross-sectional assessment of the effect of kidney and kidney-pancreas transplantation on resting left ventricular energy metabolism in type 1 diabetic-uremic patients: a phosphorous-31 magnetic resonance spectroscopy study. J Am Coll Cardiol 2005; 46(6):1085-1092. (I.F.=11.44)
27. De Cobelli F,  Esposito A, Mellone R, Papa M, Besana R, Del Maschio A. Late enhancement of a left ventricular cardiac fibroma assessed with gadolinium-enhanced cardiovascular magnetic resonance. circulation 2005; 112:242-243. (I.F.=14.60)
28. Lang CC, Gugliotta F, Santinelli V, Mesas C, Tomita T, Vicedomini G, Augello
G, Gulletta S, Mazzone P, De Cobelli F, Del Maschio A, Pappone C. Endocardial impedance mapping during circumferential pulmonary vein ablation of atrial fibrillation differentiates between atrial and venous tissue. Hearth Rhythm 2006; 3(2):171-178. (I.F.=4.44)
29. Fragasso G, Perseghin G, De Cobelli F, Esposito A, Palloshi A, Lattuada G, Scifo P, Calori G, Del Maschio A, Margonato A. Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure. Eur Hearth J 2006;27(8):942-948. (I.F.=8.92)
30. De Cobelli F, Pieroni M, Esposito A, Belloni E, Chimenti C, Mellone R, Canu T, G. Perseghin, C. Gaudio, A. Maseri, A. Frustaci,  A. Del Maschio. Delayed gadolinium-enhanced cardiac magnetic resonance in patients with chronic myocarditis presenting with heart failure or recurrent arrhythmias. J Am Coll Cardiol 2006;47(8):1649-1654. (I.F.=11.44)
31. Pieroni M, Chimenti C, De Cobelli F, Morgante E, Del Maschio A, Gaudio C, Russo MA, Frustaci A. Fabry’s disease cardiomyopathy: echocardiographic detection of endomyocardial glycosphingolipid compartmentalization.. J Am Coll Cardiol 2006;47(8):1663-1671.  (I.F.= 11.44)
32. Perseghin G, Bonfanti R, Magni S, Lattuada G, De Cobelli F, Canu T, Esposito A, Scifo P, Ntali G, Costantino F, Bosio L, Ragogna F, Del Maschio A, Chiumello G, Luzi L. Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease.Am J Physiol-Endroc M 2006; 291(4):697-703. (I.F.=3.86)
33. Perseghin G, Lattuada G, De Cobelli F, Ntali G, Esposito A, Burska A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Serum resistin and hepatic  fat content in nondiabetic individuals. J Clin Endocr Metab 2006; 91(12):5122-5. (I.F.=6.32)
34. Schaefer FK, Schaefer PJ, Altiohann C, Bourne M, De Cobelli F, Goyen M, et al. A multicenter, site-independent, blinded study to compare the diagnostic accuracy of contrast-enhanced magnetic resonance angiography using 1.0M gadobutrol (Gadovist) to intraarterial digital subtraction angiography in body arteries. Eur J Radiol 2007;61(2):315-23. (I.F:=2.34).
35. Coli S, Magnoni M, Melisurgo G, Persico P, Doldi N, De Cobelli F, Del Maschio A, Cianflone D, Maseri A. Myocardial infarction complicating the initial phase of an ovarian stimulation protocol.Int J Cardiol 2007;31;115(1): 56-7. (I.F.=3.12)
36. Fiorina P, Perseghin G, De Cobelli F, Gremizzi C, Petrelli A, Monti L, Maffi P, Luzi L, Secchi A, Del Maschio A. Altered kidney graft high-energy phosphate metabolism in kidney-transplanted end-stage renal disease type 1 diabetic patients: a cross-sectional analysis of the effect of kidney alone and kidney-pancreas transplantation. Diabetes Care  2007;30(3):597-603. (I.F:=7.35).
37. Perseghin G, Lattuada G, De Cobelli F, Ragogna F, Ntali G, Esposito A, Belloni E, Canu T, Terruzzi I, Scifo P, Del Maschio A, Luzi L. Habitual physical activity is associated with intrahepatic fat content in humans. Diabetes Care 2007; 30(3):683-688. (I.F:=7.35).
38. Belloni E, De Cobelli F, Esposito A, Mellone R, Gentinetta F, Meloni C, Del Maschio A. Myocarditis associated with clozapine studied by cardiovascular magnetic resonance. J Cardiov Magn Reson 2007; 9:591-593. (I.F.=2.15)
39. Perseghin G, Ntali G, De Cobelli F, Lattuada G, Esposito A, Belloni E, Canu T, Costantino F, Ragogna F, Scifo P, Del Maschio A, Luzi L. Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance. Diabetes Care 2007; 30(6):1520-6. (I.F:=7.35).
40. Perseghin G, De Cobelli F, Esposito A, Lattuada G, Terruzzi I, La Torre A, Belloni E, Canu T, Scifo P, Del Maschio A, Luzi L, Alberti G. Effect of the sporting discipline on the right and left ventricular morphology and function of elite male track runners: a magnetic resonance imaging and phosphorus 31 spectroscopy study. Am Heart J 2007; 154(5):937-42. (I.F:=4.29).
41. Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation. J Clin Endocrinol Metab 2007;92(12):4883-8. (I.F:=6.32).
42. Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Ntali G, Ragogna F, Canu T, Scifo P, Del Maschio A, Luzi L. Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver. Hepatology 2008; 47(1):51-58. (I.F.=11.35)
43. Manfredi AA, Capobianco A, Esposito A, De Cobelli F, Canu T, Monno A, Raucci A, Sanvito F, Doglioni C, Nawroth PP, Bierhaus A, Bianchi ME, Rovere-Querini P, Del Maschio A. Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes. J Immunol 2008; 180(4):2270-2275. (I.F:=6.00).
44. Scotti C, Camnasio F, Rizzo N, Fontana F, De Cobelli F, Peretti GM, Fraschini G. Mammary-type myofibroblastoma of popliteal fossa. Skeletal Radiol 2008; 37(6):549-553. (I.F:=1.08).
45. Chimenti C, Hamdani N, Boontje NM, De Cobelli F, Esposito A, Bronzwear  JC, Stienen GJ, Russo MA, Paulus WJ, Frustaci A, van der Velden J. Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease.  2008;172(6):1482-90. Am J Pathol 2008;172(6):1482-90. (I.F:=5.70)
46. Belloni E, De Cobelli F, Esposito A, Mellone R, Perseghin G, Canu T, Del Maschio A. MRI of cardiomyopathy.Am J Roentgenol 2008; 191: 1702-1710 (I.F.=2.94).
47. Esposito A, De Cobelli F, Perseghin G, Pieroni M, Belloni E, Mellone R, Canu T, Gentinetta F, Scifo P, Chimenti C, Frustaci A, Luzi L, Maseri A, Del Maschio A. Impaired left ventricular energy metabolism in patients with Hypertrophic Cardiomyopathy is related to the extension of Fibrosis at Gadolinium Delayed Enhanced MR Imaging. Heart 2009;95(3):228-33. (I.F:=4.96)
48. Perseghin G, De Cobelli F, Esposito A, Belloni E, Lattuada G, Canu T, Invernizzi PL, Ragogna F, La Torre A, Scifo P, Alberti G, Del Maschio A, Luzi L. Left ventricular function and energy metabolism in middle-aged men undergoing long-lasting sustained aerobic oxidative training. Heart 2009 Apr;95(8):630-5. (I.F:=4.96)
49. Marano R, De Cobelli F, Floriani I, Becker C, Herzog C, Centonze M, Morana G, Gualdi GF, Ligabue G, Pontone G, Catalano C, Chiappino D, Midiri M, Simonetti G, Marchisio F, Olivetti L, Fattori R, Bonomo L, Del Maschio A; NIMISCAD Study Group. Italian multicenter, prospective study to evaluate the negative predictive value of 16- and 64-slice MDCT imaging in patients scheduled for coronary angiography (NIMISCAD-Non Invasive Multicenter Italian Study for Coronary Artery Disease). Eur Radiol 2009;19(5):1114-23 (I.F:=3.65)
50. Morbiducci U, Ponzini R, Rizzo G, Cadioli M, Esposito A, De Cobelli F, Del Maschio A, Montevecchi FM, Redaelli A. In Vivo Quantification of Helical Blood Flow in Human Aorta by Time-Resolved Three-Dimensional Cine Phase Contrast Magnetic Resonance Imaging. Ann Biomed Eng 2009;37(3):516-31. (I.F:=2.60)
51. De Cobelli F,  Esposito A, Belloni E, Pieroni M, Perseghin G, Chimenti C, Frustaci A, Del Maschio A. Delayed-gadolinium enhancement cardiac magnetic resonance for differentiation of Anderson-Fabry disease from symmetric hypertrophic cardiomyopathy. Am J Roentgenol 2009;192(3):97-102 (I.F. 2.94)
52. Melissano G, Bertoglio L, Civelli V, Amato AC, Coppi G, Civilini E, Calori G, De Cobelli F, Del Maschio A, Chiesa R. Demonstration of the Adamkiewicz artery by multidetector computed tomography angiography analysed with the open-source software OsiriX. Eur J Vasc Endovasc Surg. 2009;37(4):395-400. (I.F. 3.00)
53. Esposito A. De Cobelli F, Belloni E, Ravelli S, Scotti R, Sabbadini MG, Del Maschio A. Magnetic resonance imagin of a hypereosinophilic endocarditis with apical thrombotic obliteration in Churg-Strauss Syndrome complicated with acute abdominal aortic embolic occlusion. Int J Cardiol 2009 [Epub ahead of print] (I.F. 3.12)
54. Perna L, Fiorino C, Cozzarini C, Broggi S, Cattaneo GM, De Cobelli F, Mangili P, Di Muzio N, Calandrino R. Sparing the penile bulb in the radical irradiation of clinically localised prostate carcinoma: A comparison between MRI and CT prostatic apex definition in 3DCRT, Linac-IMRT and Helical Tomotherapy. Radiother Oncol 2009; 93(1):57-63. (I.F. 3.99)
55. Perseghin G, Caumo A, Lattuada G, De Cobelli F, Ntali G, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance. Diabetic Med 2009;26(9):847-54. (I.F. 3.17)
56. Mezzi G, Arcidiacono PG, Carrara S, Perri F, Petrone MC, De Cobelli F, Gusmini S, Staudacher C, Del Maschio A, Testoni PA. Endoscopic ultrasound and magnetic resonance imaging for re-staging rectal cancer after radiotherapy. World J Gastroenterol 2009; 28;15(44):5563-7. (I.F. 2.08)
57. Gregorc V, Citterio G, Vitali G, Spreafico A, Scifo P, Borri A, Donadoni G, Rossoni G, Corti A, Caligaris-Cappio F, Maschio AD, Esposito A, De Cobelli F, Dell’acqua F, Troysi A, Bruzzi P, Lambiase A, Bordignon C. Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours. Eur J Cancer 2009 Nov 7. [Epub ahead of print] (I.F. 4.47)
58. Magnoni M, Esposito A, Coli S, Scuteri L, De Cobelli F, Cianflone D,  Del Maschio A, Maseri A. Two Different Mechanisms of Myocardial Ischemia Involving 2 Separate Myocardial Segments in a Patient With Normal Coronary Angiography. Circulation 2010 Jan 5;121(1):e1-3. (I.F.=14.60)

Il titolare del presente curriculum vitae, pubblicato online sul portale www.unisr.it, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.