Clementi Nicola Professore AssociatoMedicineMEDS-03/A - Microbiologia e microbiologia clinica

Nicola Clementi is Associate Professor of Medical Microbiology and Clinical Microbiology at Vita-Salute San Raffaele University in Milan and serves as Microbiologist and Virologist at IRCCS San Raffaele Hospital.

His professional activity lies at the interface between translational research, advanced diagnostics, and academic education, with a particular interest in understanding host–pathogen interactions and applying genomic technologies to infectious disease medicine.

After obtaining his Master's Degree in Biological Sciences from the Università Politecnica delle Marche and completing his postgraduate specialization in Microbiology and Virology at Vita-Salute San Raffaele University, he pursued his academic career within the same institution, serving as Adjunct Professor from 2012 to 2015, Assistant Professor (RTD-A) from 2016 to 2020, and Assistant Professor (RTD-B) from 2021 to 2023. In 2009, he was a Visiting Scientist at the Queen's Medical Centre, University of Nottingham (UK), conducting research in molecular virology. Since 2024, he has held the position of Associate Professor of Medical Microbiology and Clinical Microbiology.

At IRCCS San Raffaele Hospital, since 2022 he has coordinated the Molecular Microbiology and Drug-Resistance Sequencing Unit, dedicated to the development and implementation of next-generation sequencing (NGS)-based approaches for infectious disease diagnostics and antimicrobial resistance profiling. The unit focuses on the genomic characterization of viral and bacterial pathogens, the application of metagenomics in clinical settings, and the development of innovative diagnostic strategies for complex infections, including central nervous system infections, infective endocarditis, and osteoarticular infections. Since 2020, he has also coordinated virological activities within the Biosafety Level 3 (BSL-3) laboratory, where he oversees the isolation and phenotypic characterization of emerging viruses, including SARS-CoV-2 and Mpox virus. In addition, he serves as consultant microbiologist for the Institute's Hematopoietic Stem Cell Transplant Program.

Professor Clementi's scientific activity focuses on molecular virology, infection immunology, and the genomics of clinically relevant microorganisms. His main research interests include emerging and re-emerging viral infections, mechanisms of viral transmission and adaptation, the development and characterization of human monoclonal antibodies for therapeutic and diagnostic purposes, antimicrobial resistance investigated through advanced genomic approaches, and the interplay between the microbiota and the immune system. In recent years, he has made significant contributions to understanding immune responses against SARS-CoV-2, characterizing viral variants through next-generation sequencing, and developing innovative models for the study of viral infections.

Since 2025, he has coordinated the G2P Microbe–Host Dynamics Lab, a research laboratory dedicated to investigating host–microbe interactions through multidisciplinary approaches integrating microbiology, immunology, genomics, and molecular biology. He coordinates and participates in numerous national and international competitive research projects in the fields of emerging infectious diseases, antimicrobial resistance, and novel therapeutic strategies. These include the regional IN SIGNO project funded by the Lombardy Foundation for Biomedical Research (FRRB), initiatives supported by the Italian Ministry of University and Research through PRIN grants, and activities within the national INF-ACT programme dedicated to emerging infectious diseases.

Teaching represents a central component of his institutional activity. He serves as Coordinator of the Microbiology course within the International MD Program (IMDP), Coordinator of the Microbiology course in the BSc programme in Biotechnological Research in Medicine, and Coordinator of the Molecular Virology course in the MSc programme in Biotechnology and Medical Biology. He is actively involved in teaching within undergraduate medical and biotechnology curricula as well as postgraduate specialization schools, contributing to the education and training of students, residents, and young researchers. He is Director of Studies of the PhD Programme in Clinical and Experimental Medicine and a faculty member of the National PhD Programme dedicated to One Health approaches to infectious diseases. Throughout his academic career, he has supervised or co-supervised more than forty undergraduate and postgraduate theses, including specialization dissertations.

Professor Clementi is the author of more than one hundred peer-reviewed scientific publications, contributing to landmark studies in the fields of virology, immunology, and clinical microbiology. His scientific output has received more than 3,300 citations indexed in Scopus. By integrating basic research, diagnostic activity, and academic education, Nicola Clementi promotes a multidisciplinary approach aimed at translating scientific knowledge into clinical practice, with the goal of developing innovative strategies for the prevention, diagnosis, and treatment of infectious diseases.

• ORCID: 0000-0002-1822-9861
• Scopus ID: 24802102000
• Web of Science ResearcherID: G-8545-2014
• Scholar: https://scholar.google.it/citations?user=vL09u9sAAAAJ&hl=it
• IRCCS San Raffaele Scientific Institute: https://research.hsr.it/en/divisions/immunology-transplantation-and-infectious-diseases/nicola-clementi.html
• San Raffaele Hospital - OSR:  https://medicinadilaboratorio.hsr.it/static/upl/Cd/CdS_02-2025Italiano2.pdf

 

UniSR UNIFIND: https://unifind.unisr.it/get/person/clementi-nicola