Kahlberg Andrea Luitz Professore AssociatoMedicineMED/22
ssociate Professor of Vascular Surgery, Vita-Salute San Raffaele University School of Medicine, Milan, Italy
Chief Resident, Department of Vascular Surgery, San Raffaele Hospital, Milan, Italy
Place and date of birth:
Milan, January 31, 1981
1999 High School diploma, Liceo Classico G. Parini, Milan
2005 Medical Degree, 110/110 summa cum laude, honorable mention, at Vita-Salute San Raffaele University School of Medicine, Milan
2006: National Board of Medical Examiners, Milan
2011: Board Certification in Vascular Surgery, at Vita-Salute San Raffaele University School of Medicine, Milan (Director: Prof. Roberto Chiesa); 70/70 cum laude
Execution of more than 8,000 vascular or endovascular surgical operations, of which 3000 as first operator, mainly related to the treatment, in election or emergency, of:
- Abdominal and thoracic aortic aneurysms, by means of surgical reconstruction (bypass) or endovascular treatment (stent-grafts / endoprostheses)
- Cerebrovascular disesase - Carotid, vertebral or subclavian artery stenosis (endarterectomy or angioplasty / stent)
- Lower limb ischemia, by means of surgical reconstruction (bypass) or endovascular treatment (angioplasty / PTA / stent)
- Thoracic outlet syndrome, by means of muscular lysis (scalenotomy) or removal of anomalous ribs
- Venous insufficiency of the lower limbs, by means of surgery (saphenectomy / phlebectomy) or endovascular (radiofrequency ablation of the saphenous vein)
Execution of about 25,000 diagnostic tests of Vascular Surgery, including non-invasive (Doppler ultrasound) and invasive vascular diagnostic examinations (angiography).
From 2006 to 2014: Lecturer, Ancillary Courses in Vascular Surgery, Vita-Salute San Raffaele University School of Medicine.
Since 2008: Tutor for qualifying activities in Surgery and Surgical Specialties, Vita-Salute San Raffaele University School of Medicine, San Raffaele Hospital
2009 - 2010: Tutor of 9 editions of the course "Planning and sizing of aortic disease with OsiriX” held at San Raffaele Scientific Institute, Milan (Directors: Prof. Roberto Chiesa, Prof. Germano Melissano ).
2011: Coordinator of the Seminar "The disease of the visceral arteries" held at San Raffaele Scientific Institute, part of the educational program of the aggregated Residency Program of Vascular Surgery in Lumbardy
From 2011 to 2014: Lecturer of the Residency Program in Vascular Surgery, Vita-Salute San Raffaele University School of Medicine, Milan (Director: Prof. Roberto Chiesa), carrying out formal and practical teaching.
2014: Coordinator of the course "Planning EVAR: from workstation to treatment", held at San Raffaele Scientific Institute
2014 – today: Tenured professor at Vita-Salute San Raffaele University School of Medicine, with teaching duties in the Degree Course of Medicine and Surgery, in the International MD Program, Degree Course in Nursing, Degree Course of Dental Hygienist
2014 – present: Thesis co-advisor, Vita-Salute San Raffaele University School of Medicine - Milano
2014 – present: Coordinator of the project “VASCULAR SURGERY PROGRAM - From Medical Students to Medical Doctors”, for students of the III-IV-V-VI year of the Degree Course in Medicine and Surgery and the International MD Program, Vita-Salute San Raffaele University School of Medicine - Milano
2015: Visiting Professor at University Hospital Zürich - CH, Cardio-Thoracic-Vascular Department (Director: Prof. Dr. Med. Mario Lachat, FECTS, FEBVS)
2016: Course director “Hands-on EVAR Endovascular course on simulators” during the 7th International Congress Aortic and Peripheral Surgery "How To Do It" - Milano, Italy
2016 – 2017: Course director “Aortic Complex Surgery Workshop” (3 editions) IRCCS San Raffaele - Milano, Italy
2018 – 2019: Course director “Challenging Anatomy: Practical TEVAR Workshop” (2 editions) IRCCS San Raffaele - Milano, Italy
2019: Co-Convenor of 3 workshops of the ESVS Academy, during the Annual Meeting of the European Society for Vascular Surgery (Hamburg, Germany)
2008 - 2010: Coordinator of the multi-center research project "Italian National Registry for the study of the results of endovascular treatment for aortoesophageal and aortobronchial fistulas, and for fistulas secondary to the placement of endovascular thoracic aortic stent-grafts"
2009 - present: Researcher of the Functional Unit "Study and treatment of aortic disease Unit", San Raffaele Scientific Institute
2009 - 2010: Scientific collaborator of the international multicenter registry "RESTORE" on thoracic endovascular aorticrepair with the Relay stent-graft
2011 - 2013: Co-Investigator for the multicenter international trial "A Clinical Study of the Safety and Performance of the Treovance Stent-Graft with Navitel Delivery System for Patients With infrarenal Abdominal Aortic Aneurysms" (Protocol no. IP-0007-10)
2011 - 2018: Research Coordinator for the international multicenter trial "OvationTM Abdominal Stent Graft System Post-Market Study" (Protocol no. 771-0008)
2011 - 2016: Research Coordinator for the international multicenter trial "Zenith TX2-Low-Profile (LP) Clinical Study (TX2-LP)" (ClinicalTrials.gov Identifier: NCT00923754)
2011 - 2012: Research Coordinator for the international multicenter trial "ABSORB BTK - A clinical evaluation of the bioresorbable Everolimus-Eluting Vascular Scaffold System for the treatment of subjects with critical limb ischemia from occlusive vascular disease of the tibial arteries" (ClinicalTrials.gov Identifier: NCT01341340)
2013 - 2015: Research Coordinator for the international multicenter trial "The Activ8 Study - A multicenter non-randomized controlled study to evaluate Cre8 BTK performance in patients with critical limb ischemia" (Protocol no. P31301)
2013 – 2014: Investigator for the international study "New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: the European Registry of Endovascular Aortic Repair Complications", in collaboration with the EuRec study group.
2013 – 2015: Investigator for the international study "Aorto-bronchial and aorto-pulmonary fistulation after thoracic endovascular aortic repair: an analysis from the European Registry of Endovascular Aortic Repair Complications (EuREC)", in collaboration with the EuRec study group.
2013 – 2016: Principal Investigator of the national multicenter study MAEFISTO (Multicenter Study on Aorto-Enteric Fistulization after Stent-grafting of the Abdominal Aorta)
2014 – present: Investigator of the randomized prospective study “CURITIBA TRIAL - CUstodiol vs RInger: what is The Intrarenal Best Agent?” (ClinicalTrials.gov Identifier: NCT02327611)
2015 – present: Investigator of the randomized prospective study “NIMAS - Monitoraggio neurofisiologico intraoperatorio nella chirurgia aortica” (ClinicalTrials.gov Identifier: NCT02644681)
2015 – present: Investigator of the international sponsored trial “Insight: Studio multicentrico sponsorizzato, in aperto, prospettico, post-approvazione sul sistema di innesto stent INCRAFT® AAA in soggetti con aneurismi aortici addominali” (ClinicalTrials.gov Identifier: NCT02477111; Promotore: Cordis Corp.)
2016 – present: Investigator of the international sponsored trial STP185 “PQ Bypass Stent Graft System Long Segment Lesion Peripheral Artery Revascularization Feasibility Study” (ClinicalTrials.gov Identifier: NCT03128424; Promotore PQ Bypass Medical)
2016 – present: Investigator of the international sponsored trial STP115 “ PQ Bypass Systems for Femoropopliteal Bypass II STP115” (ClinicalTrials.gov Identifier: NCT02471638; Promotore PQ Bypass Medical)
2016 – present: Local Principal Investigator of the international first-in-human study “Innovative Sirolimus self expanding drug-eluting stent for the treatment of peripheral disease: evaluation of safety and efficacy. The ILLUMINA study” (Protocollo N. P41302; Responsabile dello Studio: Cardiovascular European Research Center - CERC)
2016 – present: Local Principal Investigator of the international randomized trial “Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities (VOYAGER PAD)” (ClinicalTrials.gov Identifier: NCT02504216; Promotore: Bayer)
2016 – present: Investigator of the international sponsored trial “Prot. 10219493DOC - Valiant Evo International Clinical Trial” (ClinicalTrials.gov Identifier: NCT02625324; Promotore: Medtronic Bakken Research Center B.V.)
2016 – present: Investigator of the international trial "Paraplegia Prevention in Aortic Aneurysm Repair by Thoraco-abdominal Staging with ‘Minimally-Invasive Segmental Artery Coil- Embolization’: A Randomized Controlled Multi-center Trial (PAPA-ARTIS)", vincitore di finanziamento EUROPEAN COMMISSION Horizon 2020 - Research and Innovation Framework Programme (Tot. EU Grant: € 5,913,922.50; Grant for San Raffaele Hospital: € 166,369) Call: H2020-SC1-2016-RTD Funding scheme: RIA Proposal number: 733203.
2017 – present: Investigator of the prospective local study STEAR: “Evaluation of STaged Endovascular Aneurysm Repair in the management of thoracoabdominal pathology by means of branched and fenestrated devices” Clinical Trials.gov: NCT03342755
2017 – present: Local Principal investigator of the international randomized sponsored trial EMINENT: “A randomized trial comparing the ELUVIA™ drug-eluting stent versus bare Metal self-expanding nitINol stEnts in the treatmeNt of superficial femoral and/or proximal popliteal arTeries” (ClinicalTrials.gov Identifier: NCT02921230; Sponsor: Boston Scientific International SA)
2017 – present: Investigator of the prospective local study PAXA: “Percutaneous Axillary Access in the Endovascular treatment of thoracoabdominal aortic pathology”. Clinical Trials.gov: NCT03223311
2017 – present: Investigator of the prospective local study PEVAR-PRO: “Approccio totalmente percutaneo al trattamento endovascolare degli aneurismi aortici”. Clinical Trials.gov: NCT03484013
2018: Good Clinical Practices Course certification (including ICH E6, Revision 2 Changes)
2018 – present: Investigator of the prospective local study FETOPT: “Evaluation of supra-aortic trunks debranching techniques in open arch repair by means of Frozen Elephant Trunk procedure with two configurations of the Jotec E-Vita hybrid graft.” Clinical Trials.gov: NCT03600077
2018 – present: Investigator of the prospective local study SAPE :“Occlusione endovascolare mediante Plug dell’arteria succlavia prevertebrale propedeutico a procedure aortiche chirurgiche o endovascolari”. Clinical Trials.gov: NCT03620006
2018 – present: Investigator of the prospective local study p-AAA: "Evaluation of open surgical and endovascular treatment of abdominal aortic pathology with hostile necks, para-/juxra-renal and sovrarinal pathology at mid and long term and stratification of the results according to the theoretical equivalent endovascular repair". Clinical Trials.gov: NCT03608683
2018 – present: Investigator for the international multi-center physician-initiated prospective study “STABILISE: A physician-initiated, international, multi-center, prospective and retrospective, non randomized, observational registry of patients with acute/subacute type B aortic dissection treated by means of the STABILISE technique”. Clinical Trials.gov: NCT03707743
2018 – present: Investigator of the prospective local study TVAC: "Studio clinico di ricerca spontaneo, randomizzato e controllato sulla prevenzione delle complicanze della ferita chirurgica per patologia aneurismatica dell’aorta toraco addominale mediante l’utilizzo del sistema a pressione topica negativa “PREVENA™”. Clinical Trials.gov NCT03512470
2018 – 2019: Local Principal investigator of the randomized international trial GE-012-106 “ Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque™ Injection 320 mgI/mL) on Renal Function in Adults with Chronic Kidney Disease (CKD) Stage III or Stage IV Who Have Undergone Endovascular Aneurysm Repair (EVAR)” (ClinicalTrials.gov Identifier: NCT03119662; Sponsor GE Healthcare Ltd.)
2018 – present: Local Principal investigator of the international multicenter study VLFDC “ Contemporary Diagnosis and Management of Aortic Graft Infection” (Promotore: Vascular Low Frequency Disease Consortium - VLFDC)
Reviewer of scientific journals:
Annals of Vascular Surgery (dal 2010)
Journal of Cardiovascular Surgery (dal 2013)
Eurointervention (dal 2014)
Journal of Endovascular Therapy (dal 2015)
JACC - Journal of American College of Cardiology (dal 2019)
Since 2006: Member of the European Society for Vascular Surgery (ESVS)
Since 2010: Member of the Italian Society of Vascular and Endovascular Surgery (SICVE)
2015 – 2017: Vice-President of the Italian College of Assistant Professors in Vascular Surgery
2018 – 2019: President of the Italian College of Assistant Professors in Vascular Surgery
Publications and congress presentations
Author of 68 full scientific publications in international scientific "peer-reviewed" journals cited, in the search engines PubMed / Scopus (11 as first author, 3 as last author, 17 as corresponding author; h-index = 18)
Editor of 2 books of Vascular Surgery, and author of 25 chapters included in 17 books related to Vascular Surgery.
Author or co-author of more than 120 original articles and abstracts published in national and international journals or proceedings relating to oral communications held in major national or international congresses of Vascular Surgery.
Invited speaker and Faculty member of more than 100 international conferences, including: Annual Meeting of the European Society of Vascular Surgery (ESVS), Annual Meeting of the European Society of Cardiovascular Surgery (ESCVS), Veith Symposium (New York), Annual Meeting of the European Association of Cardio-Thoracic Surgery (EACTS), Charing Cross symposium (London), Congresso Internacional de Cirurgia Endovascular (CICE, Sao Paulo), European Congress of Trauma and Emergency Surgery (ESTES), Siena Vascular and Endovascular Course (SIVEC), Roma C.A.P.V.T. Mundi – Carotid Aorta Peripheral Vascular Treatment (Roma),Vascular International Congress (VIP, Padua), Lisbon International Forum on Vascular Diseases (Lisbon), Aortic Surgery: How To Do It (HTDI, Milano), Leipzig Interventional Course (LINC), International Symposium of Endovascular Surgery (Spain), Annual Meeting and Postgraduate Course of the Cardiovascular and Interventional Radiological Society Of Europe (CIRSE), Annual Meeting of the Brazilian Society of Angiology and Vascular Surgery (SBACV).
Lista delle 15 pubblicazioni più significative:
Steiner, S., Sauguet, A., Langhoff, R., Kahlberg, A., Thieme, M., Zeller, T., Garot, P., Commeau, P., Cremonesi, A., Marone, E.M., Scheinert, D.
First-in-Human Experience With Sirolimus-Eluting Self-Expanding Stent for Femoropopliteal Lesions.
(2019) Journal of the American College of Cardiology, 74 (17), pp. 2216-2218.
Kahlberg, A., Mascia, D., Bertoglio, L., Loschi, D., Grandi, A., Melissano, G., Chiesa, R.
New technical approach for type B dissection: From the PETTICOAT to the STABILISE concept
(2019) Journal of Cardiovascular Surgery, 60 (3), pp. 281-288.
Kahlberg, A., Grandi, A., Loschi, D., Vermassen, F., Moreels, N., Chakfé, N., Melissano, G., Chiesa, R.
A systematic review of infected descending thoracic aortic grafts and endografts
(2019) Journal of Vascular Surgery, 69 (6), pp. 1941-1951.e1.
Kahlberg, A., Rinaldi, E., Tshomba, Y., Spelta, S., Mascia, D., Melissano, G., Chiesa, R.
Volumetric analysis of aneurysm thrombosis after thoracic endovascular aortic repair predicts postoperative changes in platelet count and coagulation parameters
(2018) Journal of Cardiovascular Surgery, 59 (3), pp. 419-427.
Kahlberg, A., Ferrante, A.M.R., Miloro, R., Mascia, D., Bertoglio, L., Baccellieri, D., Melissano, G., Chiesa, R.
Late patency of reconstructed visceral arteries after open repair of thoracoabdominal aortic aneurysm
(2018) Journal of Vascular Surgery, 67 (4), pp. 1017-1024.
Kahlberg, A., Melissano, G., Mascia, D., Loschi, D., Grandi, A., Chiesa, R.
How to best treat infectious complications of open and endovascular thoracic aortic repairs
(2017) Seminars in Vascular Surgery, 30 (2-3), pp. 95-102.
Kahlberg, A., Montorfano, M., Cambiaghi, T., Bertoglio, L., Melissano, G., Chiesa, R.
Endovascular Stent-Grafting of the Ascending Aorta for Symptomatic Parietal Thrombus
(2016) Journal of Endovascular Therapy, 23 (6), pp. 969-972.
Kahlberg, A., Rinaldi, E., Piffaretti, G., Speziale, F., Trimarchi, S., Bonardelli, S., Melissano, G., Chiesa, R., Kahlberg, A., Rinaldi, E., Apruzzi, L., Tshomba, Y., Chiesa, R., Piffaretti, G., Castelli, P., Capoccia, L., Sirignano, P., Speziale, F., Segreti, S., Trimarchi, S., Cervi, E., Bonardelli, S., Costantini, E., Baratta, V., Bellosta, R., Sarcina, A.
Results from the Multicenter Study on Aortoenteric Fistulization After Stent Grafting of the Abdominal Aorta (MAEFISTO)
(2016) Journal of Vascular Surgery, 64 (2), pp. 313-320.e1.
Kahlberg, A., Melissano, G., Tshomba, Y., Leopardi, M., Chiesa, R.
Strategies to treat thoracic aortitis and infected aortic grafts
(2015) Journal of Cardiovascular Surgery, 56 (2), pp. 269-280.
Tshomba, Y., Kahlberg, A., Melissano, G., Coppi, G., Marone, E., Ferrari, D., Lembo, R., Chiesa, R.
Comparison of renal perfusion solutions during thoracoabdominal aortic aneurysm repair
(2014) Journal of Vascular Surgery, 59 (3), pp. 623-633.
Zipfel, B., Chiesa, R., Kahlberg, A., Marone, E.M., Rousseau, H., Kaskarelis, I., Riambau, V., Coppi, G., Ferro, C., Sassi, C., Esteban, C., Mangialardi, N., Tealdi, D.G., Nano, G., Schoder, M., Funovics, M., Buz, S., Hetzer, R.
Endovascular repair of traumatic thoracic aortic injury: Final results from the relay endovascular registry for thoracic disease
(2014) Annals of Thoracic Surgery, 97 (3), pp. 774-780.
Czerny, M., Eggebrecht, H., Sodeck, G., Weigang, E., Livi, U., Verzini, F., Schmidli, J., Chiesa, R., Melissano, G., Kahlberg, A., Amabile, P., Harringer, W., Horacek, M., Erbel, R., Park, K.-H., Beyersdorf, F., Rylski, B., Blanke, P., Canaud, L., Khoynezhad, A., Lonn, L., Rousseau, H., Trimarchi, S., Brunkwall, J., Gawenda, M., Dong, Z., Fu, W., Schuster, I., Grimm, M.
New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: The european registry of endovascular aortic repair complications
(2014) European Journal of Cardio-thoracic Surgery, 45 (3), art. no. ezt393, pp. 452-457.
Kahlberg, A., Mascia, D., Marone, E.M., Logaldo, D., Tshomba, Y., Chiesa, R.
The Bolton Treovance endograft: Single center experience
(2014) Journal of Cardiovascular Surgery, 55 (1), pp. 77-84.
Chiesa, R., Kahlberg, A., Mascia, D., Tshomba, Y., Civilini, E., Melissano, G.
Use of a novel hybrid vascular graft for sutureless revascularization of the renal arteries during open thoracoabdominal aortic aneurysm repair
(2014) Journal of Vascular Surgery, 60 (3), pp. 622-630.
Kahlberg, A., Tshomba, Y., Marone, E.M., Castellano, R., Melissano, G., Chiesa, R.
Current results of a combined endovascular and open approach for the treatment of aortoesophageal and aortobronchial fistulae
(2014) Annals of Vascular Surgery, 28 (7), pp. 1782-1788.
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