Kahlberg Andrea Luitz Professore AssociatoMedicinaMED/22

Biografia

Pubblicazioni

English version

Biografia

Posizione attuale:

Dal 2019: Professore associato di Chirurgia Vascolare con funzioni assistenziali, Università Vita-Salute San Raffaele, Milano

Dal 2019: aiuto-primario e coordinatore dell’Area Emergenze Vascolari presso la Divisione di Chirurgia Vascolare dell’IRCCS Ospedale San Raffaele, Milano.

Dal 2014: Ricercatore a tempo determinato di Chirurgia Vascolare con funzioni assistenziali, Università Vita-Salute San Raffaele, Milano

Dal 2011: Medico Specialista Chirurgo Vascolare presso la Divisione di Chirurgia Vascolare dell’IRCCS Ospedale San Raffaele, Milano.

Luogo e data di nascita:

Milano, 31 Gennaio 1981

Attività clinica:

Esecuzione di più di 8000 interventi di chirurgia vascolare e/o endovascolare, di cui 3000 in qualità di primo operatore, con principali interessi rivolti verso il trattamento, in elezione o in urgenza di:

  • Aneurismi e dissezioni dell’aorta addominale e toracica, mediante ricostruzione chirurgica (bypass) o trattamento endovascolare (endoprotesi)
  • stenosi carotidea, succlavia o vertebrale (endoarterectomia o angioplastica / stent)
  • ischemia degli arti inferiori, mediante ricostruzione chirurgica (bypass) o trattamento endovascolare (angioplastica / PTA / stent)
  • sindrome dello stretto toracico, mediante lisi muscolare (scalenotomia) o asportazione di coste sovrannumerarie
  • insufficienza venosa degli arti inferiori, mediante intervento chirurgico (safenectomia / flebectomie) o endovascolare (termoablazione della safena con radiofrequenza)

Esecuzione di circa 25.000 esami diagnostici di Chirurgia Vascolare, inclusa la diagnostica vascolare non invasiva (EcoColorDoppler) e invasiva (angiografia).

Studi:

1999: Maturità Classica, Liceo Classico G. Parini, Milano

2005: Laurea in Medicina e Chirurgia con votazione 110/110 e lode, menzione onorevole - Università “Vita-Salute” San Raffaele – Milano

2006: Abilitazione alla professione di Medico Chirurgo ed iscrizione all’Albo dei Medici e Chirurghi di Milano

2011: Specializzazione in Chirurgia Vascolare - Università “Vita-Salute” San Raffaele - Milano (Direttore: Prof. Roberto Chiesa) con votazione 70/70 e lode

Incarichi didattici:

2006 – 2014: Collaboratore dell’Università “Vita-Salute” San Raffaele svolgendo attività didattica teorica-pratica nell’ambito dei Corsi Elettivi di Chirurgia Vascolare per i Corsi di Laurea Specialistica e Magistrale in Medicina e Chirurgia

Dal 2008 ad oggi: Tutor per le Attività Professionalizzanti in Chirurgia e Specializzazioni Chirurgiche presso l’Università “Vita-Salute” San Raffaele – Milano nell’ambito del Corso di Laurea Specialistica in Medicina e Chirurgia

2009 – 2010: Tutor delle 9 edizioni del Corso “Planning and sizing” della patologia aortica con Osirix, tenuto presso l’Università “Vita-Salute” San Raffaele di Milano (Direttori: Prof. Roberto Chiesa, Prof. Germano Melissano).

2011: Coordinatore del Seminario “La patologie delle arterie viscerali” tenutosi presso l’Istituto Scientifico Universitario San Raffaele nell’ambito dei Seminari Lombardi di Chirurgia Vascolare 2011-2012  (parte integrante del programma didattico delle Scuole Aggregate Lombarde di Chirurgia Vascolare)

Dal 2011 ad oggi: Docente (a contratto sino al 2014, poi di ruolo) della Scuola di Specializzazione in Chirurgia Vascolare presso l’Università “Vita-Salute” San Raffaele - Milano (Direttore: Prof. Roberto Chiesa), svolgendo attività di docenza formale e pratica.

2014: Coordinatore del Corso “Planning EVAR: dalla workstation al trattamento”  tenutosi presso l’Istituto Scientifico Universitario San Raffaele

2014 – ad oggi: Docente di ruolo presso l’Università “Vita-Salute” San Raffaele - Milano, con incarichi di didattica all’interno del Corso di Laurea Magistrale in Medicina e Chirurgia (docente del corso integrato di Clinica Chirurgica, responsabile del corso elettivo “Urgenze ed emergenze in chirurgia vascolare: tempo di pace e tempo di guerra”), dell’International MD Program (corso integrato Clinical Surgery), Corso di Laurea in Infermieristica (corso integrato di Infermieristica clinica in area chirurgica), Corso di Laurea in Igiene Dentale (corso integrato di Principi di medicina generale)

2014 – ad oggi: Correlatore di numerose Tesi di Laurea, all’interno del Corso di Laurea Magistrale in Medicina e Chirurgia, Università “Vita-Salute” San Raffaele - Milano

2014 – ad oggi: Coordinatore del progetto “VASCULAR SURGERY PROGRAM - From Medical Students to Medical Doctors”, finalizzato alla programmazione, coordinazione e valutazione dei cicli di internato in Chirurgia Vascolare per gli studenti del III-IV-V-VI anno di Corso di Laurea Magistrale in Medicina e Chirurgia e del Corso di Laurea Magistrale in Medicina e Chirurgia - MD Program

2015: Visiting Professor presso University Hospital Zürich - CH, Dipartimento Cardio-Toraco-Vascolare (Direttore: Prof. Dr. Med. Mario Lachat, FECTS, FEBVS) svolgendo attività didattica e di ricerca riguardanti la riparazione aortica toracica e toracico-addominale, ECMO, la chirurgia carotidea e periferica e le tecniche avanzate ibride e endovascolari (vedi certificazione allegata)

2016: Coordinatore del Corso “Hands-on EVAR Endovascular course on simulators” in occasione del 7th International Congress Aortic and Peripheral Surgery "How To Do It" - Milano, Italy

2016 – 2017: Coordinatore del Corso “Aortic Complex Surgery Workshop” (3 edizioni) IRCCS San Raffaele - Milano, Italy

2018 – 2019: Coordinatore del Corso “Challenging Anatomy: Practical TEVAR Workshop” (2 edizioni) IRCCS San Raffaele - Milano, Italy

2019: Co-Convenor di 3 workshops all’interno dell’ESVS Academy, Annual Meeting of the European Society for Vascular Surgery (Hamburg, Germany)

Ricerca scientifica:

2008 – 2010: Coordinatore del progetto di ricerca multicentrico “Registro nazionale Italiano per lo studio dei risultati del trattamento endovascolare delle fistole aortoesofagee ed aortobronchiali, e le fistole secondarie al posizionamento di endoprotesi nell’aorta toracica”

2009 – ad oggi: Ricercatore nell’ambito dell’Unità Funzionale di Ricerca “Study and treatment of aortic disease Unit” dell’Istituto Scientifico Universitario San Raffaele

2009 – 2010: Collaboratore scientifico del registro internazionale multicentrico “RESTORE” sulle endoprotesi aortiche toraciche Relay

2011 – 2013: Co-Investigator per lo studio multicentrico internazionale “A Clinical Study of the Safety and Performance of the Treovance Stent-Graft with Navitel Delivery System for Patients With Infrarenal Abdominal Aortic Aneurysms” (Protocollo num. IP-0007-10)

2011 – 2016: Research Coordinator per lo studio multicentrico internazionale “Zenith TX2-Low-Profile (LP) Clinical Study (TX2-LP)” (ClinicalTrials.gov Identifier:  NCT00923754)

2011 – 2018: Research Coordinator per lo studio multicentrico internazionale “OvationTM Abdominal Stent Graft System Post-Market Study” (Protocollo num. 771-0008)

2011 – 2012: Research Coordinator per lo studio multicentrico internazionale “ABSORB BTK – A clinical evaluation of the Everolimus Eluting Bioresorbable Vascular Scaffold System for the treatment of subjects with critical limb ischemia from occlusive vascular disease of the tibial arteries” (ClinicalTrials.gov Identifier:  NCT01341340)

2013 – 2015: Research Coordinator per lo studio multicentrico internazionale “The Activ8 Study – A multicenter non randomized study to evaluate Cre8 BTK performances in patients with critical limb ischemia” (Protocollo num. P31301)

2013 – 2014: Investigator dello studio multicentrico internazionale spontaneo "New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: the European Registry of Endovascular Aortic Repair Complications", in collaborazione con il gruppo di ricerca europeo EuRec.

2013 – 2015: Investigator dello studio multicentrico internazionale spontaneo "Aorto-bronchial and aorto-pulmonary fistulation after thoracic endovascular aortic repair: an analysis from the European Registry of Endovascular Aortic Repair Complications (EuREC)", in collaborazione con il gruppo di ricerca europeo EuRec.

2013 – 2016    Principal Investigator e responsabile scientifico a carattere nazionale dello studio spontaneo MAEFISTO (Multicenter Study on Aorto-Enteric Fistulization after Stent-grafting of the Abdominal Aorta)

2014 – ad oggi: Investigator dello studio spontaneo monocentrico prospettico randomizzato “CURITIBA TRIAL - CUstodiol vs RInger: what is The Intrarenal Best Agent?” (ClinicalTrials.gov Identifier: NCT02327611)

2015 – ad oggi: Investigator per lo studio spontaneo prospettico randomizzato “NIMAS - Monitoraggio neurofisiologico intraoperatorio nella chirurgia aortica” (ClinicalTrials.gov Identifier: NCT02644681)

2015 – ad oggi: Investigator dello studio multicentrico internazionale sponsorizzato “Insight: Studio multicentrico sponsorizzato, in aperto, prospettico, post-approvazione sul sistema di innesto stent INCRAFT® AAA in soggetti con aneurismi aortici addominali” (ClinicalTrials.gov Identifier: NCT02477111; Promotore: Cordis Corp.)

2015: Certificazione di svolgimento del corso internazionale di Good Clinical Practices per il personale coinvolto in studi di ricerca  (NIDA Clinical Trials Network)

2016 – ad oggi: Investigator dello studio multicentrico internazionale sponsorizzato STP185 “PQ Bypass Stent Graft System Long Segment Lesion Peripheral Artery Revascularization Feasibility Study” (ClinicalTrials.gov Identifier: NCT03128424; Promotore PQ Bypass Medical)

2016 – ad oggi: Investigator dello studio multicentrico internazionale sponsorizzato STP115 “ PQ Bypass Systems for Femoropopliteal Bypass II STP115” (ClinicalTrials.gov Identifier: NCT02471638; Promotore PQ Bypass Medical)

2016 – ad oggi: Principal Investigator locale dello studio multicentrico internazionale first-in-human “Innovative Sirolimus self expanding drug-eluting stent for the treatment of peripheral disease: evaluation of safety and efficacy. The ILLUMINA study” (Protocollo N. P41302; Responsabile dello Studio: Cardiovascular European Research Center - CERC)

2016 – ad oggi: Principal Investigator locale dello studio multicentrico internazionale sponsorizzato randomizzato “Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities (VOYAGER PAD)” (ClinicalTrials.gov Identifier: NCT02504216; Promotore: Bayer)

2016 – ad oggi: Investigator dello studio multicentrico internazionale sponsorizzato “Prot. 10219493DOC - Valiant Evo International Clinical Trial” (ClinicalTrials.gov Identifier: NCT02625324; Promotore: Medtronic Bakken Research Center B.V.)

2016 – ad oggi: Investigator dello studio spontaneo multicentrico internazionale "Paraplegia Prevention in Aortic Aneurysm Repair by Thoraco-abdominal Staging with ‘Minimally-Invasive Segmental Artery Coil- Embolization’: A Randomized Controlled Multi-center Trial (PAPA-ARTIS)", vincitore di finanziamento EUROPEAN COMMISSION Horizon 2020 - Research and Innovation Framework Programme (Tot. EU Grant: € 5,913,922.50; Grant for San Raffaele Hospital: € 166,369) Call: H2020-SC1-2016-RTD Funding scheme: RIA Proposal number: 733203.

2017 – ad oggi: Investigator per lo studio spontaneo prospettico STEAR: “Evaluation of STaged Endovascular Aneurysm Repair in the management of thoracoabdominal pathology by means of branched and fenestrated devices” Clinical Trials.gov: NCT03342755

2017 – ad oggi: Principal investigator locale dello studio multicentrico internazionale sponsorizzato EMINENT: “A randomized trial comparing the ELUVIA™ drug-eluting stent versus bare Metal self-expanding nitINol stEnts in the treatmeNt of superficial femoral and/or proximal popliteal arTeries” (ClinicalTrials.gov Identifier: NCT02921230; Sponsor: Boston Scientific International SA)

2017 – ad oggi: Investigator per lo studio spontaneo prospettico PAXA: “Percutaneous Axillary Access in the Endovascular treatment of thoracoabdominal aortic pathology”. Clinical Trials.gov: NCT03223311

2017 – ad oggi: Investigator per lo studio spontaneo prospettico PEVAR-PRO: “Approccio totalmente percutaneo al trattamento endovascolare degli aneurismi aortici”. Clinical Trials.gov: NCT03484013

2018: Certificazione di svolgimento del corso internazionale di aggiornamento in Good Clinical Practices per il personale coinvolto in studi di ricerca  (including ICH E6, Revision 2 Changes)

2018 – ad oggi: Investigator per lo studio spontaneo prospettico FETOPT: “Evaluation of supra-aortic trunks debranching techniques in open arch repair by means of Frozen Elephant Trunk procedure with two configurations of the Jotec E-Vita hybrid graft.” Clinical Trials.gov: NCT03600077

2018 – ad oggi: Investigator per lo studio spontaneo prospettico SAPE :“Occlusione endovascolare mediante Plug dell’arteria succlavia prevertebrale propedeutico a procedure aortiche chirurgiche o endovascolari”. Clinical Trials.gov: NCT03620006

2018 – ad oggi: Investigator per lo studio spontaneo prospettico p-AAA: "Evaluation of open surgical and endovascular treatment of abdominal aortic pathology with hostile necks, para-/juxra-renal and sovrarinal pathology at mid and long term and stratification of the results according to the theoretical equivalent endovascular repair". Clinical Trials.gov: NCT03608683

2018 – ad oggi: Investigator per lo studio spontaneo multicentrico internazionale “STABILISE: A physician-initiated, international, multi-center, prospective and retrospective, non randomized, observational registry of patients with acute/subacute type B aortic dissection treated by means of the STABILISE technique”.  Clinical Trials.gov: NCT03707743

2018 – ad oggi: Investigator per lo studio spontaneo prospettico randomizzato TVAC: "Studio clinico di ricerca spontaneo, randomizzato e controllato sulla prevenzione delle complicanze della ferita chirurgica per patologia aneurismatica dell’aorta toraco addominale mediante l’utilizzo del sistema a pressione topica negativa “PREVENA™”. Clinical Trials.gov NCT03512470

2018 – 2019: Principal investigator locale dello studio multicentrico internazionale randomizzato GE-012-106 “ Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque™ Injection 320 mgI/mL) on Renal Function in Adults with Chronic Kidney Disease (CKD) Stage III or Stage IV Who Have Undergone Endovascular Aneurysm Repair (EVAR)”  (ClinicalTrials.gov Identifier: NCT03119662; Sponsor GE Healthcare Ltd.)

2018 – ad oggi: Principal investigator locale dello studio multicentrico internazionale VLFDC “ Contemporary Diagnosis and Management of Aortic Graft Infection” (Promotore: Vascular Low Frequency Disease Consortium - VLFDC)

Revisore per le riviste scientifiche:

Annals of Vascular Surgery (dal 2010)

Journal of Cardiovascular Surgery (dal 2013)

Eurointervention (dal 2014)

Journal of Endovascular Therapy (dal 2015)

JACC - Journal of American College of Cardiology (dal 2019)

Affiliazioni:

Dal 2006: Membro della Società Europea di Chirurgia Vascolare (European Society for Vascular Surgery, ESVS)

Dal 2010: Membro della Società Italiana di Chirurgia Vascolare ed Endovascolare (SICVE)

2015 – 2017: Vice-Presidente del Collegio Nazionale dei Ricercatori Universitari di Chirurgia Vascolare

2018 – 2019: Presidente del Collegio Nazionale dei Ricercatori Universitari di Chirurgia Vascolare
 

Pubblicazioni

 

Lista delle 15 pubblicazioni più significative:

 

Steiner, S., Sauguet, A., Langhoff, R., Kahlberg, A., Thieme, M., Zeller, T., Garot, P., Commeau, P., Cremonesi, A., Marone, E.M., Scheinert, D.

First-in-Human Experience With Sirolimus-Eluting Self-Expanding Stent for Femoropopliteal Lesions.

(2019) Journal of the American College of Cardiology, 74 (17), pp. 2216-2218.

 

Kahlberg, A., Mascia, D., Bertoglio, L., Loschi, D., Grandi, A., Melissano, G., Chiesa, R.

New technical approach for type B dissection: From the PETTICOAT to the STABILISE concept

(2019) Journal of Cardiovascular Surgery, 60 (3), pp. 281-288.

 

Kahlberg, A., Grandi, A., Loschi, D., Vermassen, F., Moreels, N., Chakfé, N., Melissano, G., Chiesa, R.

A systematic review of infected descending thoracic aortic grafts and endografts

(2019) Journal of Vascular Surgery, 69 (6), pp. 1941-1951.e1.

 

Kahlberg, A., Rinaldi, E., Tshomba, Y., Spelta, S., Mascia, D., Melissano, G., Chiesa, R.

Volumetric analysis of aneurysm thrombosis after thoracic endovascular aortic repair predicts postoperative changes in platelet count and coagulation parameters

(2018) Journal of Cardiovascular Surgery, 59 (3), pp. 419-427.

 

Kahlberg, A., Ferrante, A.M.R., Miloro, R., Mascia, D., Bertoglio, L., Baccellieri, D., Melissano, G., Chiesa, R.

Late patency of reconstructed visceral arteries after open repair of thoracoabdominal aortic aneurysm

(2018) Journal of Vascular Surgery, 67 (4), pp. 1017-1024.

 

Kahlberg, A., Melissano, G., Mascia, D., Loschi, D., Grandi, A., Chiesa, R.

How to best treat infectious complications of open and endovascular thoracic aortic repairs

(2017) Seminars in Vascular Surgery, 30 (2-3), pp. 95-102.

 

Kahlberg, A., Montorfano, M., Cambiaghi, T., Bertoglio, L., Melissano, G., Chiesa, R.

Endovascular Stent-Grafting of the Ascending Aorta for Symptomatic Parietal Thrombus

(2016) Journal of Endovascular Therapy, 23 (6), pp. 969-972.

 

Kahlberg, A., Rinaldi, E., Piffaretti, G., Speziale, F., Trimarchi, S., Bonardelli, S., Melissano, G., Chiesa, R., Kahlberg, A., Rinaldi, E., Apruzzi, L., Tshomba, Y., Chiesa, R., Piffaretti, G., Castelli, P., Capoccia, L., Sirignano, P., Speziale, F., Segreti, S., Trimarchi, S., Cervi, E., Bonardelli, S., Costantini, E., Baratta, V., Bellosta, R., Sarcina, A.

Results from the Multicenter Study on Aortoenteric Fistulization After Stent Grafting of the Abdominal Aorta (MAEFISTO)

(2016) Journal of Vascular Surgery, 64 (2), pp. 313-320.e1.

 

Kahlberg, A., Melissano, G., Tshomba, Y., Leopardi, M., Chiesa, R.

Strategies to treat thoracic aortitis and infected aortic grafts

(2015) Journal of Cardiovascular Surgery, 56 (2), pp. 269-280.

 

Tshomba, Y., Kahlberg, A., Melissano, G., Coppi, G., Marone, E., Ferrari, D., Lembo, R., Chiesa, R.

Comparison of renal perfusion solutions during thoracoabdominal aortic aneurysm repair

(2014) Journal of Vascular Surgery, 59 (3), pp. 623-633.

 

Zipfel, B., Chiesa, R., Kahlberg, A., Marone, E.M., Rousseau, H., Kaskarelis, I., Riambau, V., Coppi, G., Ferro, C., Sassi, C., Esteban, C., Mangialardi, N., Tealdi, D.G., Nano, G., Schoder, M., Funovics, M., Buz, S., Hetzer, R.

Endovascular repair of traumatic thoracic aortic injury: Final results from the relay endovascular registry for thoracic disease

(2014) Annals of Thoracic Surgery, 97 (3), pp. 774-780.

 

Czerny, M., Eggebrecht, H., Sodeck, G., Weigang, E., Livi, U., Verzini, F., Schmidli, J., Chiesa, R., Melissano, G., Kahlberg, A., Amabile, P., Harringer, W., Horacek, M., Erbel, R., Park, K.-H., Beyersdorf, F., Rylski, B., Blanke, P., Canaud, L., Khoynezhad, A., Lonn, L., Rousseau, H., Trimarchi, S., Brunkwall, J., Gawenda, M., Dong, Z., Fu, W., Schuster, I., Grimm, M.

New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: The european registry of endovascular aortic repair complications

(2014) European Journal of Cardio-thoracic Surgery, 45 (3), art. no. ezt393, pp. 452-457.

 

Kahlberg, A., Mascia, D., Marone, E.M., Logaldo, D., Tshomba, Y., Chiesa, R.

The Bolton Treovance endograft: Single center experience

(2014) Journal of Cardiovascular Surgery, 55 (1), pp. 77-84.

 

Chiesa, R., Kahlberg, A., Mascia, D., Tshomba, Y., Civilini, E., Melissano, G.

Use of a novel hybrid vascular graft for sutureless revascularization of the renal arteries during open thoracoabdominal aortic aneurysm repair

(2014) Journal of Vascular Surgery, 60 (3), pp. 622-630.

 

Kahlberg, A., Tshomba, Y., Marone, E.M., Castellano, R., Melissano, G., Chiesa, R.

Current results of a combined endovascular and open approach for the treatment of aortoesophageal and aortobronchial fistulae

(2014) Annals of Vascular Surgery, 28 (7), pp. 1782-1788.

 

English version

ssociate Professor of Vascular Surgery, Vita-Salute San Raffaele University School of Medicine, Milan, Italy

 

Chief Resident, Department of Vascular Surgery, San Raffaele Hospital, Milan, Italy

 

 

Place and date of birth:

 

Milan, January 31, 1981

 

 

Education:

 

1999 High School diploma, Liceo Classico G. Parini, Milan

 

2005 Medical Degree, 110/110 summa cum laude, honorable mention, at Vita-Salute San Raffaele University School of Medicine, Milan

 

2006: National Board of Medical Examiners, Milan

 

2011: Board Certification in Vascular Surgery, at Vita-Salute San Raffaele University School of Medicine, Milan (Director: Prof. Roberto Chiesa); 70/70 cum laude

 

 

Clinical activity:

 

Execution of more than 8,000 vascular or endovascular surgical operations, of which 3000 as first operator, mainly related to the treatment, in election or emergency, of:

- Abdominal and thoracic aortic aneurysms, by means of surgical reconstruction (bypass) or endovascular treatment (stent-grafts / endoprostheses)

- Cerebrovascular disesase - Carotid, vertebral or subclavian artery stenosis (endarterectomy or angioplasty / stent)

- Lower limb ischemia, by means of surgical reconstruction (bypass) or endovascular treatment (angioplasty / PTA / stent)

- Thoracic outlet syndrome, by means of muscular lysis (scalenotomy) or removal of anomalous ribs

- Venous insufficiency of the lower limbs, by means of surgery (saphenectomy / phlebectomy) or endovascular (radiofrequency ablation of the saphenous vein)

 

Execution of about 25,000 diagnostic tests of Vascular Surgery, including non-invasive (Doppler ultrasound) and invasive vascular diagnostic examinations (angiography).

 

 

Teaching duties:

 

From 2006 to 2014: Lecturer, Ancillary Courses in Vascular Surgery, Vita-Salute San Raffaele University School of Medicine.

 

Since 2008: Tutor for qualifying activities in Surgery and Surgical Specialties, Vita-Salute San Raffaele University School of Medicine, San Raffaele Hospital

 

2009 - 2010: Tutor of 9 editions of the course "Planning and sizing of aortic disease with OsiriX” held at San Raffaele Scientific Institute, Milan (Directors: Prof. Roberto Chiesa, Prof. Germano Melissano ).

 

2011: Coordinator of the Seminar "The disease of the visceral arteries" held at San Raffaele Scientific Institute, part of the educational program of the aggregated Residency Program of Vascular Surgery in Lumbardy

 

From 2011 to 2014: Lecturer of the Residency Program in Vascular Surgery, Vita-Salute San Raffaele University School of Medicine, Milan (Director: Prof. Roberto Chiesa), carrying out formal and practical teaching.

 

2014: Coordinator of the course "Planning EVAR: from workstation to treatment", held at  San Raffaele Scientific Institute

 

2014 – today: Tenured professor at Vita-Salute San Raffaele University School of Medicine, with teaching duties in the Degree Course of Medicine and Surgery, in the International MD Program, Degree Course in Nursing, Degree Course of Dental Hygienist

 

2014 – present: Thesis co-advisor, Vita-Salute San Raffaele University School of Medicine - Milano

 

2014 – present: Coordinator of the project “VASCULAR SURGERY PROGRAM - From Medical Students to Medical Doctors”, for students of the III-IV-V-VI year of the Degree Course in Medicine and Surgery and the International MD Program, Vita-Salute San Raffaele University School of Medicine - Milano

 

2015: Visiting Professor at University Hospital Zürich - CH, Cardio-Thoracic-Vascular Department (Director: Prof. Dr. Med. Mario Lachat, FECTS, FEBVS)

 

2016: Course director “Hands-on EVAR Endovascular course on simulators” during the 7th International Congress Aortic and Peripheral Surgery "How To Do It" - Milano, Italy

 

2016 – 2017: Course director “Aortic Complex Surgery Workshop” (3 editions) IRCCS San Raffaele - Milano, Italy

 

2018 – 2019: Course director “Challenging Anatomy: Practical TEVAR Workshop” (2 editions) IRCCS San Raffaele - Milano, Italy

 

2019: Co-Convenor of 3 workshops of the ESVS Academy, during the Annual Meeting of the European Society for Vascular Surgery (Hamburg, Germany)

 

 

 

Scientific research:

 

2008 - 2010: Coordinator of the multi-center research project "Italian National Registry for the study of the results of endovascular treatment for aortoesophageal and aortobronchial fistulas, and for fistulas secondary to the placement of endovascular thoracic aortic stent-grafts"

 

2009 - present: Researcher of the Functional Unit "Study and treatment of aortic disease Unit", San Raffaele Scientific Institute

 

2009 - 2010: Scientific collaborator of the international multicenter registry "RESTORE" on thoracic endovascular aorticrepair with the Relay stent-graft

 

2011 - 2013: Co-Investigator for the multicenter international trial "A Clinical Study of the Safety and Performance of the Treovance Stent-Graft with Navitel Delivery System for Patients With infrarenal Abdominal Aortic Aneurysms" (Protocol no. IP-0007-10)

 

2011 - 2018: Research Coordinator for the international multicenter trial "OvationTM Abdominal Stent Graft System Post-Market Study" (Protocol no. 771-0008)

 

2011 - 2016: Research Coordinator for the international multicenter trial "Zenith TX2-Low-Profile (LP) Clinical Study (TX2-LP)" (ClinicalTrials.gov Identifier: NCT00923754)

 

2011 - 2012: Research Coordinator for the international multicenter trial "ABSORB BTK - A clinical evaluation of the bioresorbable Everolimus-Eluting Vascular Scaffold System for the treatment of subjects with critical limb ischemia from occlusive vascular disease of the tibial arteries" (ClinicalTrials.gov Identifier: NCT01341340)

 

2013 - 2015: Research Coordinator for the international multicenter trial "The Activ8 Study - A multicenter non-randomized controlled study to evaluate Cre8 BTK performance in patients with critical limb ischemia" (Protocol no. P31301)

  

2013 – 2014: Investigator for the international study "New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: the European Registry of Endovascular Aortic Repair Complications", in collaboration with the EuRec study group.

 

2013 – 2015: Investigator for the international study "Aorto-bronchial and aorto-pulmonary fistulation after thoracic endovascular aortic repair: an analysis from the European Registry of Endovascular Aortic Repair Complications (EuREC)", in collaboration with the EuRec study group.

 

2013 – 2016: Principal Investigator of the national multicenter study MAEFISTO (Multicenter Study on Aorto-Enteric Fistulization after Stent-grafting of the Abdominal Aorta)

 

2014 – present: Investigator of the randomized prospective study “CURITIBA TRIAL - CUstodiol vs RInger: what is The Intrarenal Best Agent?” (ClinicalTrials.gov Identifier: NCT02327611)

 

2015 – present: Investigator of the randomized prospective study “NIMAS - Monitoraggio neurofisiologico intraoperatorio nella chirurgia aortica” (ClinicalTrials.gov Identifier: NCT02644681)

 

2015 – present: Investigator of the international sponsored trial “Insight: Studio multicentrico sponsorizzato, in aperto, prospettico, post-approvazione sul sistema di innesto stent INCRAFT® AAA in soggetti con aneurismi aortici addominali” (ClinicalTrials.gov Identifier: NCT02477111; Promotore: Cordis Corp.)

 

2016 – present: Investigator of the international sponsored trial STP185 “PQ Bypass Stent Graft System Long Segment Lesion Peripheral Artery Revascularization Feasibility Study” (ClinicalTrials.gov Identifier: NCT03128424; Promotore PQ Bypass Medical)

 

2016 – present: Investigator of the international sponsored trial STP115 “ PQ Bypass Systems for Femoropopliteal Bypass II STP115” (ClinicalTrials.gov Identifier: NCT02471638; Promotore PQ Bypass Medical)

 

2016 – present: Local Principal Investigator of the international first-in-human study “Innovative Sirolimus self expanding drug-eluting stent for the treatment of peripheral disease: evaluation of safety and efficacy. The ILLUMINA study” (Protocollo N. P41302; Responsabile dello Studio: Cardiovascular European Research Center - CERC)

 

2016 – present: Local Principal Investigator of the international randomized trial “Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities (VOYAGER PAD)” (ClinicalTrials.gov Identifier: NCT02504216; Promotore: Bayer)

 

2016 – present: Investigator of the international sponsored trial “Prot. 10219493DOC - Valiant Evo International Clinical Trial” (ClinicalTrials.gov Identifier: NCT02625324; Promotore: Medtronic Bakken Research Center B.V.)

 

2016 – present: Investigator of the international trial "Paraplegia Prevention in Aortic Aneurysm Repair by Thoraco-abdominal Staging with ‘Minimally-Invasive Segmental Artery Coil- Embolization’: A Randomized Controlled Multi-center Trial (PAPA-ARTIS)", vincitore di finanziamento EUROPEAN COMMISSION Horizon 2020 - Research and Innovation Framework Programme (Tot. EU Grant: € 5,913,922.50; Grant for San Raffaele Hospital: € 166,369) Call: H2020-SC1-2016-RTD Funding scheme: RIA Proposal number: 733203.

 

2017 – present: Investigator of the prospective local study STEAR: “Evaluation of STaged Endovascular Aneurysm Repair in the management of thoracoabdominal pathology by means of branched and fenestrated devices” Clinical Trials.gov: NCT03342755

 

2017 – present: Local Principal investigator of the international randomized sponsored trial EMINENT: “A randomized trial comparing the ELUVIA™ drug-eluting stent versus bare Metal self-expanding nitINol stEnts in the treatmeNt of superficial femoral and/or proximal popliteal arTeries” (ClinicalTrials.gov Identifier: NCT02921230; Sponsor: Boston Scientific International SA)

 

2017 – present: Investigator of the prospective local study PAXA: “Percutaneous Axillary Access in the Endovascular treatment of thoracoabdominal aortic pathology”. Clinical Trials.gov: NCT03223311

 

2017 – present: Investigator of the prospective local study PEVAR-PRO: “Approccio totalmente percutaneo al trattamento endovascolare degli aneurismi aortici”. Clinical Trials.gov: NCT03484013

 

2018: Good Clinical Practices Course certification  (including ICH E6, Revision 2 Changes)

 

2018 – present: Investigator of the prospective local study FETOPT: “Evaluation of supra-aortic trunks debranching techniques in open arch repair by means of Frozen Elephant Trunk procedure with two configurations of the Jotec E-Vita hybrid graft.” Clinical Trials.gov: NCT03600077

 

2018 – present: Investigator of the prospective local study SAPE :“Occlusione endovascolare mediante Plug dell’arteria succlavia prevertebrale propedeutico a procedure aortiche chirurgiche o endovascolari”. Clinical Trials.gov: NCT03620006

 

2018 – present: Investigator of the prospective local study p-AAA: "Evaluation of open surgical and endovascular treatment of abdominal aortic pathology with hostile necks, para-/juxra-renal and sovrarinal pathology at mid and long term and stratification of the results according to the theoretical equivalent endovascular repair". Clinical Trials.gov: NCT03608683

 

2018 – present: Investigator for the international multi-center physician-initiated prospective study “STABILISE: A physician-initiated, international, multi-center, prospective and retrospective, non randomized, observational registry of patients with acute/subacute type B aortic dissection treated by means of the STABILISE technique”.  Clinical Trials.gov: NCT03707743

 

2018 – present: Investigator of the prospective local study TVAC: "Studio clinico di ricerca spontaneo, randomizzato e controllato sulla prevenzione delle complicanze della ferita chirurgica per patologia aneurismatica dell’aorta toraco addominale mediante l’utilizzo del sistema a pressione topica negativa “PREVENA™”. Clinical Trials.gov NCT03512470

 

2018 – 2019: Local Principal investigator of the randomized international trial GE-012-106 “ Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque™ Injection 320 mgI/mL) on Renal Function in Adults with Chronic Kidney Disease (CKD) Stage III or Stage IV Who Have Undergone Endovascular Aneurysm Repair (EVAR)”  (ClinicalTrials.gov Identifier: NCT03119662; Sponsor GE Healthcare Ltd.)

 

2018 – present: Local Principal investigator of the international multicenter study VLFDC “ Contemporary Diagnosis and Management of Aortic Graft Infection” (Promotore: Vascular Low Frequency Disease Consortium - VLFDC)

 

Reviewer of scientific journals:

 

Annals of Vascular Surgery (dal 2010)

Journal of Cardiovascular Surgery (dal 2013)

Eurointervention (dal 2014)

Journal of Endovascular Therapy (dal 2015)

JACC - Journal of American College of Cardiology (dal 2019)

 

 

Scientific Societies:

 

Since 2006: Member of the European Society for Vascular Surgery (ESVS)

 

Since 2010: Member of the Italian Society of Vascular and Endovascular Surgery (SICVE)

 

2015 – 2017: Vice-President of the Italian College of Assistant Professors in Vascular Surgery

 

2018 – 2019: President of the Italian College of Assistant Professors in Vascular Surgery

 

 

Publications and congress presentations

 

Author of 68 full scientific publications in international scientific "peer-reviewed" journals cited, in the search engines PubMed / Scopus (11 as first author, 3 as last author, 17 as corresponding author; h-index = 18)

 

Editor of 2 books of Vascular Surgery, and author of 25 chapters included in 17 books related to Vascular Surgery.

 

Author or co-author of more than 120 original articles and abstracts published in national and international journals or proceedings relating to oral communications held in major national or international congresses of Vascular Surgery.

 

Invited speaker and Faculty member of more than 100 international conferences, including: Annual Meeting of the European Society of Vascular Surgery (ESVS), Annual Meeting of the European Society of Cardiovascular Surgery (ESCVS), Veith Symposium (New York), Annual Meeting of the European Association of Cardio-Thoracic Surgery (EACTS), Charing Cross symposium (London), Congresso Internacional de Cirurgia Endovascular (CICE, Sao Paulo), European Congress of Trauma and Emergency Surgery (ESTES), Siena Vascular and Endovascular Course (SIVEC), Roma C.A.P.V.T. Mundi – Carotid Aorta Peripheral Vascular Treatment (Roma),Vascular International Congress (VIP, Padua), Lisbon International Forum on Vascular Diseases (Lisbon), Aortic Surgery: How To Do It (HTDI, Milano), Leipzig Interventional Course (LINC), International Symposium of Endovascular Surgery (Spain), Annual Meeting and Postgraduate Course of the Cardiovascular and Interventional Radiological Society Of Europe (CIRSE), Annual Meeting of the Brazilian Society of Angiology and Vascular Surgery (SBACV).

 

Il titolare del presente curriculum vitae, pubblicato online sul portale www.unisr.it, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.