Mazzeo Salvatore Ricercatore tempo determinato tipo bMedicine

Dr. Salvatore Mazzeo is a Neurologist and Researcher (RTDB) at Vita-Salute San Raffaele University. His research focuses on investigating the clinical, cognitive, genetic, and biological aspects of early and atypical presentations of dementia, leveraging advanced techniques in artificial intelligence. He conducts his clinical activity at the Neurology Unit of the IRCCS San Donato.

RESEARCHER ID - RESEARCHER'S UNIQUE IDENTIFIER

https://orcid.org/0000-0001-5985-5060
https://www.scopus.com/authid/detail.uri?authorId=57189687311
https://scholar.google.com/citations?hl=it&user=SCXMIUwAAAAJ

EDUCATION

2024, Ph.D. in Neuroscience, University of Florence

2020, Training in Neurology, University of Florence

2019, Advanced Course "Neuropsychological assessment of neurodegenerative diseases", University of Pisa

2015, Medical Degree, Vita-Salute San Raffaele University, Milan

FELLOWSHIPS

2023, Visiting Research Fellow, Dementia Research Centre, University College London, London, UK

CLINICAL ACTIVITY

2024 - present, Neurology Unit, IRCCS "San Donato", San Donato Milanese

2020 - 2023, Intensive Neurorehabilitation Unit, IRCCS "Don Carlo Gnocchi", Florence

2016 - 2020, Neurology resident, University Hospital Careggi, Florence

RESEARCH ACTIVITY

2024 - present, Senior Researcher (RTDB) in Neurology, Vita-Salute San Raffaele University, Milan

2023 - 2024, Senior Researcher, University Hospital Careggi, Florence

2020 - 2024, PhD student in Neuroscience, University of Florence

2022, Research Assistant, IRCCS "Don Carlo Gnocchi", Florence

2015 - 2016, Medical Research Collaborator, Institute of Experimental Neurology (INSPE), IRCCS, San Raffaele Hospital, Milan

ROLES IN SCIENTIFIC SOCIETIES

2021 - present, Elected Member of the Board of Directors of SINdem Tuscany section

AWARDS

2024, Junior Faculty Award - 18th International Conference on Alzheimer's & Parkinson's Diseases and related neurological disorders

2023, American Academy of Neurology’s (AAN) International Scholarship Award

2021, 2nd place winner of the "Research in 3 minutes" Award - European Researchers' Night, University of Florence

2020, Best poster, Congress of the Italian Society for the Study of Dementia (SINDEM)

2020, Best poster, Winter seminar on Dementia and Neurodegenerative Disorders, Bressanone

2018, Best oral presentation, Winter seminar on Dementia and Neurodegenerative Disorders, Bressanone

MAJOR PUBBLICATIONS

1. Mazzeo S, Santangelo R, Bernasconi MP, et al. Combining Cerebrospinal Fluid Biomarkers and Neuropsychological Assessment: A Simple and Cost-Effective Algorithm to Predict the Progression from Mild Cognitive Impairment to Alzheimer’s Disease Dementia. J Alzheimers Dis. 2016;54(4):1495-1508. doi:10.3233/JAD-160360
2. Mazzeo S, Padiglioni S, Bagnoli S, et al. Assessing the effectiveness of subjective cognitive decline plus criteria in predicting the progression to Alzheimer’s disease: an 11-year follow-up study. Eur J Neurol. 2020;27(5):894-899. doi:10.1111/ene.14167
3. Mazzeo S, Emiliani F, Bagnoli S, et al. Huntingtin gene intermediate alleles influence the progression from subjective cognitive decline to mild cognitive impairment: A 14-year follow-up study. Eur J Neurol. 2022;29(6):1600-1609. doi:10.1111/ene.15291
4. Mazzeo S, Polito C, Lassi M, et al. Loss of speech and functional impairment in Alzheimer’s disease-related primary progressive aphasia: predictive factors of decline. Neurobiol Aging. 2022;117:59-70. doi:10.1016/j.neurobiolaging.2022.05.002
5. Mazzeo S, Polito C, Padiglioni S, et al. Linguistic profiles, brain metabolic patterns and rates of amyloid-β biomarker positivity in patients with mixed primary progressive aphasia. Neurobiol Aging. 2020;96:155-164. doi:10.1016/j.neurobiolaging.2020.09.004
6. Mazzeo S, Padiglioni S, Bagnoli S, et al. The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study. J Neurol. 2019;266(2):487-497. doi:10.1007/s00415-018-9164-5
7. Mazzeo S, Ingannato A, Giacomucci G, et al. Plasma neurofilament light chain predicts Alzheimer’s disease in patients with subjective cognitive decline and mild cognitive impairment: A cross-sectional and longitudinal study. Eur J Neurol. Published online October 5, 2023. doi:10.1111/ene.16089
8. Bessi V and Mazzeo S, Bagnoli S, et al. The implication of BDNF Val66Met polymorphism in progression from subjective cognitive decline to mild cognitive impairment and Alzheimer’s disease: a 9-year follow-up study. Eur Arch Psychiatry Clin Neurosci. 2020;270(4):471-482. doi:10.1007/s00406-019-01069-y
9. Giacomucci G and Mazzeo S, Bagnoli S, et al. Plasma neurofilament light chain as a biomarker of Alzheimer’s disease in Subjective Cognitive Decline and Mild Cognitive Impairment. J Neurol. 2022;269(8):4270-4280. doi:10.1007/s00415-022-11055-5
10. Bessi V, Mazzeo S, Padiglioni S, et al. From Subjective Cognitive Decline to Alzheimer’s Disease: The Predictive Role of Neuropsychological Assessment, Personality Traits, and Cognitive Reserve. A 7-Year Follow-Up Study. Journal of Alzheimer’s Disease. 2018;63(4):1523-1535. doi:10.3233/JAD-171180
11. Bessi V, Giacomucci G, Mazzeo S, et al. PER2 C111G polymorphism, cognitive reserve and cognition in subjective cognitive decline and mild cognitive impairment: a 10-year follow-up study. European Journal of Neurology. 2021;28(1):56-65. doi:10.1111/ene.14518
12. Giacomucci G, Mazzeo S, Crucitti C, et al. Plasma p-tau181 as a promising non-invasive biomarker of Alzheimer’s disease pathology in subjective cognitive decline and mild cognitive impairment. Journal of the Neurological Sciences. 2023;0(0). doi:10.1016/j.jns.2023.120805
13. Lassi M, Fabbiani C, Mazzeo S, et al. Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer’s Disease continuum? NeuroImage: Clinical. 2023;38:103407. doi:10.1016/j.nicl.2023.103407
14. Belder CRS, Marshall CR, Jiang J, Mazzeo S et al. Primary progressive aphasia: six questions in search of an answer. J Neurol. 2024;271(2):1028-1046. doi:10.1007/s00415-023-12030-4
15. Amato LG, Vergani AA, Lassi M, Fabbiani C, Mazzeo S et al. Personalized modeling of Alzheimer’s disease progression estimates neurodegeneration severity from EEG recordings. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. 2024;16(1):e12526. doi:10.1002/dad2.12526

 

Per una lista complete delle pubblicazioni e altri indicatori bibliometrici, si veda al link https://scholar.google.com/citations?hl=it&user=SCXMIUwAAAAJ

H index: 12 (Scopus), 12 (Google Scholar)

i10-index (Google Scholar): 14