Laboratori 2020/2021 - Immunologia e Oncologia di Base e Applicate

Ciascun candidato, al momento della sottomissione della domanda di ammissione, deve selezionare da 3 a 5 progetti, non necessariamente afferenti ad uno stesso curriculum, tra tutti quelli elencati nelle pagine dei curricula stessi.

5 BORSE A PROGETTO:

Borsa a progetto BAIO1

BRIGANTI ALBERTO

Unit: Urological Research Unit (URI)

BAIO1: Genomic alterations underlying immune escape mechanisms in prostate cancer:

Borsa a progetto BAIO2

DELLABONA PAOLO

 Unit: Experimental Immunology

BAIO2: Defining the metastatic immune contexture of colorectal cancer in the liver

Borsa a progetto BAIO3

GUIDOTTI LUCA 

Unit: Immunopathology

BAIO3: Combining new mouse models with single-cell imaging and genomic technologies to study COVID-19 Virology, Immunopathogenesis and Coagulopathy

Borsa a progetto BAIO4

IANNACONE MATTEO 

Unit: Dynamics of Immune Responses

BAIO4: Defining intrahepatic T cell priming events responsible for defective T cell responses

Borsa a progetto BAIO5

BIANCHI MARCO 

Unit: Chromatin Dynamics

Establishing human mesothelioma organoids

AGRESTI ALESSANDRA - FCSR Fronzaroli

Unit: In Vivo Chromatin and Transcription

Nucleosome count, genome plasticity and Epithelial-to-Mesenchymal- Transition (EMT) in cancer

BELLONE MATTEO - FCSR Fronzaroli

Unit: Cellular Immunology

Identification of the pathogenic crosstalk between gut microbiota and immune cells driving multiple myeloma progression

BOLETTA ALESSANDRA - FCSR Fronzaroli

Unit: Molecular Basis of Cystic Kidney Disorders

Characterization of Key Metabolic Alterations in Renal Cell Carcinoma

BONINI CHIARA- FCSR Fronzaroli only for the second project

Unit: Experimental Hematology

Cell therapy with genetically engineered T-cells for liver metastases from colorectal and pancreatic cancer Exploiting cutting edge technologies to hunt novel T cell receptors for adoptive immunotherapy of acute myeloid leukemia

BRENDOLAN ANDREA - FCSR Fronzaroli

Unit: Lymphoid Organ Development and Function

Role of fibroblastic stromal cells in lymphoid malignancies

CASORATI GIULIA  - FCSR Fronzaroli

Unit: Experimental Immunology

Defining the molecular bases of tumor immunesurveillance by iNKT cells to improve their therapeutic exploitation

CENCI SIMONE - FCSR Fronzaroli

Unit: Age Related Diseases

Mitohormesis in multiple myeloma

CIRILLO DANIELA - FCSR Fronzaroli

Unit: Emerging Bacterial Pathogens

Role of the immune response in the pathogenesis of Non-Tubercular Mycobacteria Lung infection

DE CURTIS IVAN - FCSR Fronzaroli

Unit: Cell Adhesion

Mechanisms of regulation of a molecular network promoting cell invasion

FOUSTERI GEORGIA - FCSR Fronzaroli only for the first project

Unit: Regulation of Adaptive Immunity

Role of follicular helper T cells in the humoral immune alterations in patients with mutations in the Wiskott Aldrich Syndrome protein before and after hematopoietic stem cell transplantation or gene therapy Immune therapy with genetically engineered regulatory T cells to establish tolerance in type 1 diabetes

GHIA PAOLO - FCSR Fronzaroli 

Division: Experimental Oncology-B-cell Neoplasia Unit

Dissecting the NFKB signaling pathway in normal and malignant B lymphocytes of Chronic Lymphocytic Leukemia Unravelling Genetic Intratumor B Lymphocyte Heterogeneity of Chronic Lymphocytic Leukemia

MONDINO ANNA - FCSR Fronzaroli

Unit: Lymphocyte Activation

Unlocking tumors to TCR/CAR engineered T cells

MONTI PAOLO- FCSR Fronzaroli

Unit: Transplant Immunology

Targeting the glucose transporter GLUT1 to control T cell activation

MUZIO MARTA - FCSR Fronzaroli

Unit: Cell Signaling

Exploring NFKBIZ-centered pathways in normal and malignant B-cells

OSTUNI RENATO - FCSR Fronzaroli

Unit: Genomics of the innate immune system

Identification of immune suppressive pathways in liver metastatic cancer

PETRELLI ALESSANDRA - FCSR Fronzaroli

Unit: Prevention of T1D - DRI

EXPLORING MOLECULAR MECHANISMS OF CD8 T CELL-MEDIATED INSULIN-RESISTANCE IN HUMAN OBESITY

POLI GUIDO - FCSR Fronzaroli

Unit: AIDS Immunopathogenesis

Role of M1/M2 Polarization of Human Macrophages in Pathogenic RNA Virus Infection Immuno-Virological Dynamics Triggered by Anti-HIV Therapy Suspension

PROTTI MARIA PIA - FCSR Fronzaroli only for the first project

Unit: Tumor Immunology

Dissecting mechanisms of chemotherapy-induced immunomodulation of T follicular helper cells in pancreatic cancer Investigating the immune contexture of liver lesions from metastatic pancreatic cancer patients

SCIELZO CRISTINA 

Unit: Malignant B cells Biology and 3D modelling

Developing a comprehensive in vitro model to recapitulate the leukemic microenvironment by the use of a 3D bio-printer

SESSA ALESSANDRO - FCSR Fronzaroli

Unit: Stem Cells & Neurogenesis

Generation and validation of artificial epigenetic silencers to reduce brain metastases

SQUADRITO MARIO LEONARDO - FCSR Fronzaroli

Unit: Targeted Cancer Gene Therapy 

Exploiting microRNA networks in tumor-associated macrophages to boost tumor immunity

TACCHETTI CARLO - FCSR Fronzaroli

Unit: CIS_Experimental Imaging Center

Translation rewiring shapes triple-negative breast cancer invasiveness and immune niche composition

TONON GIOVANNI - FCSR Fronzaroli

Unit: Functional Genomics of Cancer Unit

Single-cell genomic approaches to unravel tumor resistance

VAGO LUCA - FCSR Fronzaroli

Unit: Immunogenetics, Leukemia Genomics and Immunobiology

Cutting-edge transcriptomics to identify leukemia-intrinsic and -extrinsic correlates of defined patterns of immune escape and post-transplantation relapse

VAGO RICCARDO - FCSR Fronzaroli

Unit: Urological Research Institute

Analysis of long non-coding RNA altered in cancer progression

VENEREAU EMILIE- FCSR Fronzaroli

Unit: Chromatin Dynamics

Exploring HMGB1-directed strategies to fight cancer

VICENZI ELISA - FCSR Fronzaroli

Unit: Viral Pathogens and Biosafety

SARS-CoV-2 and COVID-19: drug repurposing and viral evolution

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