Laboratori 2019/2020 - Immunologia e oncologia di base e applicate

4 BORSE A PROGETTO:

TONON GIOVANNI- Project-Based Fellowship BAIO1

Unit: Functional Genomics of Cancer

BAIO1: single-cell genomic approaches to unravel tumor heterogeneity

IANNACONE MATTEO - Project-Based Fellowship BAIO2

Unit: Dynamics of immune responses

BAIO2: Determinants of T cell behavior within the cancerous liver

IANNACONE MATTEO - Project-Based Fellowship BAIO3

Unit: Dynamics of immune responses

BAIO3: Defining intrahepatic T cell priming events responsible for defective T cell responses

FALCONE MARIKA - Project-Based Fellowship BAIO4

Unit: Experimental Diabetes

BAIO4: Exploiting a multi-omic data integration approach to assess the role of gut-related immune modulation in multiple sclerosis

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9 borse FCSR-Fronzaroli sono destinate a candidati che optano per uno dei progetti accreditati per questa tipologia di borse.

La preferenza per una borsa FCSR-Fronzaroli dovrà essere indicata durante la compilazione del modulo elettronico per la sottomissione della domanda di ammissione, come riportato all'art. del bando di concorso.

I vincitori di una posizione con borsa FCSR- Fronzaroli o di una borsa libera devono scegliere il proprio progetto di ricerca tra quelli offerti per il Curriculum di 1° scelta. 

Conclusa la seconda fase di assegnazione tutti i progetti qui sotto elencati, che riportano la dicitura FCSR-Fronzaroli ,che non sono stati scelti dai vincitori della suddetta borsa, potranno essere scelti durante le successive fasi di ammissione da tutti gli altri candidati.

 

AGRESTI ALESSANDRA - FCSR Fronzaroli

Unit: In Vivo Chromatin and Transcription

Understand the molecular mechanisms of anti-NF-kB drugs to improve Multiple Myeloma therapy

BELLONE MATTEO - FCSR Fronzaroli

Unit: Cellular Immunology

Identification of the pathogenic crosstalk between gut microbiota and immune cells driving multiple myeloma progression

BIANCHI MARCO - FCSR Fronzaroli

Unit: Chromatin Dynamics

Establishing human mesothelioma organoids

BOLETTA ALESSANDRA - FCSR Fronzaroli

Unit: Molecular Basis of Cystic Kidney Disorders

CHARACTERIZATION OF KEY METABOLIC ALTERATIONS IN RENAL CELL CARCINOMA

BONINI CHIARA

Unit: Experimental Hematology

1. Exploiting cutting edge technologies to hunt novel T cell receptors for adoptive immunotherapy of acute myeloid leukemia 2. Adoptive cell therapy with genetically engineered T-cells for liver metastases from colorectal and pancreatic cancer

BRENDOLAN ANDREA - FCSR Fronzaroli

Unit: Lymphoid Organ Development and Function

1. Role of the stromal microenvironment in B-cell malignancies 2. Development and functional characterization of a human 3D leukemic microenvironment in a perfusion bioreactor system

CASUCCI MONICA

Unit: Innovative Immunotherapies

1. Improving the Therapeutic Index of CAR-T cell therapy for solid tumours 2. Engineering better CAR-T cells for cancer therapy

CENCI SIMONE - FCSR Fronzaroli

Unit: Age Related Diseases

Mitohormesis in multiple myeloma

DE CURTIS IVAN - FCSR Fronzaroli

Unit: Cell Adhesion

Regulatory mechanisms of invadosome assembly and function

DEGANO MASSIMO - FCSR Fronzaroli

Unit: Biocrystallography

The molecular basis of autonomous signaling in chronic lymphocytic leukemia

DELLABONA PAOLO - FCSR Fronzaroli

Unit: Experimental Immunology

Adoptive immunotherapy of hepatic cancer metastasis with functionally engineered innate-like T cells

FALCONE MARIKA - FCSR Fronzaroli

Unit: Experimental Diabetes

Assessing the role of gut barrier integrity in the pathogenesis of autoimmune diabetes

FIORINO CLAUDIO

Unit: Medical Physics

Quantifying reproducibility and repeatability of CT radiomic features to build robust predictive models for patients with pancreatic cancer

FOUSTERI GEORGIA - FCSR Fronzaroli

Unit: Regulation of Adaptive Immunity

Role of follicular helper T cells in the humoral immune alterations in patients with mutations in the Wiskott Aldrich Syndrome protein before and after hematopoietic stem cell transplantation or gene therapy

FOUSTERI GEORGIA

Unit: Regulation of Adaptive Immunity

Immune therapy with genetically engineered regulatory T cells to establish tolerance in type 1 diabetes

GREGORI SILVIA - FCSR Fronzaroli

Unit: Mechanisms of Peripheral Tolerance

Unraveling epigenetic mechanisms controlling immune tolerance

MANFREDI ANGELO - FCSR Fronzaroli

Unit: Autoimmunity and vascular Inflammation

Mitochondrial DAMPs drive vascular inflammation and autoimmunity

MONDINO ANNA - FCSR Fronzaroli

Unit: Lymphocyte Activation

Unlocking tumors to TCR/CAR engineered T cells

MONTI PAOLO

Unit: Transplant Immunology

Targeting the glucose transporter GLUT1 to control T cell activation

MUZIO MARTA - FCSR Fronzaroli

Unit: Cell Signaling

Dissecting Toll-like receptors signaling pathways in B-cell lymphoid malignancies

OSTUNI RENATO - FCSR Fronzaroli

Unit: Genomics of the innate immune system

Mechanisms of suppression of inflammatory gene expression in macrophages

POLI GUIDO - FCSR Fronzaroli

Unit: AIDS Immunopathogenesis

1. HIV-1 Infection of Macrophages: Role of M1/M2 Polarization in Reversible Proviral Latency 2. Immuno-Virological Dynamics Triggered by Anti-HIV Therapy Suspension

ROVERE-QUERINI PATRIZIA - FCSR Fronzaroli

Unit: Innate Immunity and Tissue Remodelling

Role of complement in a murine experimental model of dermatomyositis (EDM)

SCARLATTI GABRIELLA

Unit: Innate Immunity and Tissue Remodelling

Mechanisms of inhibition of HIV mucosal transmission by antibodies

SCIELZO CRISTINA

Unit: B cell neoplasia

Developing a comprehensive in vitro model to recapitulate the leukemic microenvironment by the use of a 3D bio-printer.

SESSA ALESSANDRO - FCSR Fronzaroli

Unit: Stem Cells & Neurogenesis

Generation and validation of an artificial transcription factor to epigenetically reprogram glioblastoma cells

SITIA GIOVANNI - FCSR Fronzaroli

Unit: Experimental Hepatology

Type I interferon subtypes with high in-vivo potency for the treatment of liver colorectal cancer metastases

TACCHETTI CARLO - FCSR Fronzaroli

Unit: CIS_Experimental Imaging Center

eIF2α-driven translation reprogramming as a therapeutic vulnerability in triplenegative breast cancer

VAGO RICCARDO - FCSR Fronzaroli

Unit: Urological Research Institute

Targeted delivery of toxins for the treatment of bladder cancer

VENEREAU EMILIE

Unit: Chromatin Dynamics

Exploring HMGB1-directed strategies to fight cancer

VICENZI ELISA - FCSR Fronzaroli

Unit: Viral Pathogens and Biosafety

ZIKA virus cytopathic infection of neural progenitor cells and its exploitation as oncolytic virus for brain tumors

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