Laboratori 2021/2022 - Immunologia e Oncologia di Base e Applicate

Di seguito è possibile visionare l’elenco dei Directors of Studies (e i link ai rispettivi CV) e i progetti presentati per l' a.a. 2021/2022 all'interno del curriculum in Immunologia e Oncologia di Base e Applicate

1 BORSA A PROGETTO:

Borsa a progetto BAIO1: IANNACONE MATTEO 

Unit: Dynamics of Immune Responses

BAIO1: Study the dynamics of HBsAg-specific B cells in mouse model of HBV pathogenesis

AGRESTI ALESSANDRA

Unit: In Vivo Chromatin and Transcription

Nucleosome count, genome plasticity and Epithelial-to-Mesenchymal-Transition (EMT) in cancer

BELLONE MATTEO

Unit: Cellular Immunology

Understanding the role of cytokines of the IL-17 family in multiple myeloma progression

BIANCHI MARCO 

Unit: Chromatin Dynamics

CXCR4-mediated antitumor immunization

BOLETTA ALESSANDRA

Unit: Molecular Basis of Cystic Kidney Disorders

Loss of genome repair mechanisms in the initiation and progression of renal cell carcinomas

CASUCCI MONICA

Unit: Innovative Immunotherapies

Identification of a novel CAR specificity to tackle solid malignancies

CENCI SIMONE

Unit: Age Related Diseases

Characterizing and targeting unprecedented mitochondrial vulnerabilities against multiple myeloma

CIRILLO DANIELA MARIA

Unit: Emerging Bacterial Pathogens

The role of the immune response in the pathogenesis of Non-Tubercular Mycobacteria Lung infection

DE CURTIS IVAN

Unit: Cell Adhesion

Mechanisms of regulation of a molecular network promoting cell invasion

DELLABONA PAOLO

Unit: Experimental Immunology

Adoptive immunotherapy of hepatic colorectal cancer metastasis with functionally engineered innate-like T cells

FOUSTERI GEORGIA

Unit: Regulation of Adaptive Immunity

Project 1: Role of follicular helper T cells in the humoral immune alterations in patients with mutations in the Wiskott Aldrich Syndrome protein before and after hematopoietic stem cell transplantation or gene therapy Project 2: Immune therapy with genetically engineered regulatory T cells to establish tolerance in type 1 diabetes

GHIA PAOLO

Division: Experimental Oncology-B-cell Neoplasia

Project 1: Unravelling genetic intratumor B lymphocyte heterogeneity of chronic lymphocytic leukemia Project 2:Deciphering the the role of EGR2 mutations in Chronic Lymphocytic Leukemia

GREGORI SILVIA

Unit: Mechanisms of Peripheral Tolerance

Unraveling molecular mechanisms controlling dendritic cell (DC)-mediated tolerance

KUKA MIRELA

Unit: Dynamics of Immune Responses

In depth characterization of monocyte-B cell interactions in infection and cancer

MANFREDI ANGELO

Unit: Autoimmunity and Vascular Inflammation

Mitochondrial DAMPs in vascular inflammation

MONDINO ANNA

Unit: Lymphocyte Activation

Unlocking tumors to TCR/CAR engineered T cells

MUZIO MARTA

Unit: Cell Signaling

Project 1: Exploring NFKBIZ-centered pathways in normal and malignant B-cells Project 2: Dissecting and targeting NFAT signaling in chronic lymphocytic leukemia

OSTUNI RENATO

Unit: Genomics of the innate immune system

Spatial diversity of tumor-associated macrophages

POLI GUIDO

Unit: Viral Pathogenesis and Biosafety

Project 1: Role of M1/M2 Polarization of Human Macrophages in Pathogenic RNA Virus Infection Project 2: Immuno-Virological Dynamics Triggered by Anti-HIV Therapy Suspension

SCIELZO CRISTINA 

Unit: Malignant B cells Biology and 3D modelling

Developing a comprehensive in vitro model to recapitulate the leukemic microenvironment by the use new 3D culture models.

SESSA ALESSANDRO

Unit: Stem Cells & Neurogenesis

Generation and validation of artificial epigenetic silencers to reduce brain metastases

SITIA ROBERTO

Unit: Protein Transport and Secretion, DGCB

Transmission of redox signals across compartments

TACCHETTI CARLO

Unit: CIS_Experimental Imaging Center

Translation rewiring determines triple-negative breast cancer aggressiveness: unraveling its role in metabolism and immune niche composition

TONON GIOVANNI

Unit: Functional Genomics of Cancer

Project 1: Single-cell genomic approaches to unravel cancer resistance Project 2: Unraveling how bacteria strategies are exploited by cancer cells to survive therapy

VAGO LUCA

Unit: Immunogenetics, Leukemia Genomics and Immunobiology

Identifying new actionable epigenetic drivers of leukemia immune escape

VAGO RICCARDO

Unit: Extracellular vesicles and toxins

Analysis of long non-coding RNA altered in cancer progression

VENEREAU EMILIE

Unit: Tissue Regeneration & Homeostasis

Exploring HMGB1-directed strategies to fight cancer

VICENZI ELISA

Unit: Viral Pathogens and Biosafety

SARS-CoV-2 and COVID-19: drug repurposing and viral evolution