Terapia Genica e Cellulare

Laboratori 2021/2022 - Terapia Genica e Cellulare

Di seguito è possibile visionare l’elenco dei Directors of Studies (e i link ai rispettivi CV) e i progetti presentati per l' a.a. 2021/2022 all'interno del curriculum in Terapia Genica e Celllulare

7 BORSE A PROGETTO:

BORSA A PROGETTO GCT1: AIUTI ALESSANDRO

Unit: Pathogenesis and therapy of primary immunodeficiencies

GCT1: Characterization of Mucopolysaccharidosis Type IV murine models to develop pre-clinical gene therapy strategies

BORSA A PROGETTO GCT2: CANTORE ALESSIO

Unit: Liver gene therapy

GCT2: Evaluation of the efficacy and safety of gene therapy strategies for liver metabolic diseases

BORSA A PROGETTO GCT3: CITRO ANTONIO

Unit: Diabetes Research Institute – Pancreas Bioengineering

GCT3: Human Vascularized Islet Organ (hVIO) as an extracorporeal model for the study of physiopathology and drug screening in diabetes.

BORSA A PROGETTO GCT4: DI MICCO RAFFAELLA

Unit: Senescence in Stem Cell Aging Differentiation and Cancer

GCT4: Gaining insights on hematopoietic stem cell response to endogenous DNA damage to further advance gene and cell therapies

BORSA A PROGETTO GCT5: MORTELLARO ALESSANDRA

Unit: Pathogenesis and Therapy of Primary Immunodeficiencies

GCT5: Study of disease pathogenesis and development of gene therapy for adenosine deaminase 2 deficiency

BORSA A PROGETTO GCT6: LORENZO PIEMONTI

Unit: Diabetes Research Institute - Beta Cell Differentiation Unit

GCT6: Pre-clinical approaches of cell therapy for type 1 diabetes with induced pluripotent stem cell (iPSC) – derived β cells

BORSA A PROGETTO GCT7 (TBD): LORENZO PIEMONTI

Unit: Diabetes Research Institute - Beta Cell Biology Unit

GCT7: Vanguard: Bioartificial Pancreas to Cure Type 1 Diabetes

CHIARA BONINI

Unit: Experimental Hematology

Exploiting cutting edge technologies to hunt novel T cell receptors for the immune gene therapy of acute myeloid leukemia

COLTELLA NADIA

Unit: Targeted Cancer Gene Therapy

Development of next generation tumor-directed immune-gene therapy strategies in solid cancer

DI MICCO RAFFAELLA

Unit: Senescence in Stem Cell Aging Differentiation and Cancer

Identification and targeting of senescence programs during hematopoietic stem cell aging

GENTNER BERNHARD

Unit: Translational Stem Cell & Leukemia Research

New gene therapy approaches for leukemia

GREGORI SILVIA

Unit: Mechanisms of Peripheral Tolerance

Tolerogenic approaches to prevent unwanted immune responses in protein replacement and gene therapies for Lysosomal Storage Disorders

LIDONNICI MARIA ROSA

Unit: Gene transfer into stem cell

Definition of molecular networks of erythropoiesis in beta-thalassemia

LOMBARDO ANGELO

Unit: Epigenetic regulation and targeted genome editing

Development of multifunctional editing strategies for adoptive T-cell immunotherapy of cancer

MENEGHINI VASCO

Unit: Gene/neural stem cell therapy for lysosomal storage diseases

Development of gene editing strategies targeting glial cells for the treatment of rare neurodegenerative disorders

NALDINI LUIGI

Unit: Gene transfer technologies and new gene therapy strategies

Identify the key regulators of human HSPCs engraftment in an in vivo mouse model using a gain-of-function screen

OSTUNI RENATO

Unit: Genomics of the innate immune system

Dissection and therapeutic exploitation of macrophage diversity

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