Zangrillo Alberto Professore ordinarioMedicinaMED/41

Biografia

Pubblicazioni

Biografia

Direttore dell’Unità Operativa di Anestesia e Rianimazione Generale dell’IRCCS Ospedale San Raffaele.

Direttore dell’Unità Operativa di Anestesia e Rianimazione Cardio Toraco Vascolare      dell’IRCCS Ospedale San Raffaele.

Direttore dell’Unità Operativa di Anestesia e Rianimazione dell’IRCCS San Raffaele Turro.

Professore Ordinario di Anestesia e Rianimazione.

Prorettore per le attività cliniche, Università Vita-Salute San Raffaele.

Referente Direzionale Aree Cliniche dell’IRCCS Ospedale San Raffaele.

Coordinatore dell’Area Cardiovascolare dell’IRCCS Ospedale San Raffaele.      
 

Scheda biografica

Nato il 13 Aprile 1958 a Genova.

Laurea in Medicina e Chirurgia presso l'Università degli Studi di Milano il 10 Novembre 1983. Specialità in Anestesia e Rianimazione presso l'Università degli Studi di Milano l’8 Luglio 1986.

Per la sua formazione professionale ha frequentato i seguenti centri: Queen Charlotte Hospital di Londra, Hospital de la Santa Creu I Sant Pau di Barcellona, Cardio-thoracic Centre of Monaco di Montecarlo, Hetzer Deutsches Herzzentrum – Berlin, IRCCS Ospedale San Raffaele di Milano.

Honors and Positions

Autore di oltre 500 pubblicazioni su riviste internazionali indicizzate (citate più di 18.000 volte, h-index 64), tra cui studi randomizzati su NEJM, JAMA, Circulation e British Medical Journal e 41 libri o capitoli di libri.

Visiting Professor, Universidad CES, Medellín, Colombia, 2016-2017.

Prorettore per le attività cliniche, Università Vita-Salute San Raffaele, anni 2013-2016.

Membro della Commissione Sviluppo Sanità della Regione Lombardia dal 8 Luglio 2013.

Editor in chief della rivista “Heart, Lung and Vessels” e revisore di grant per donors internazionali (tra cui la Swiss National Science Foundation), 2009- 2015.

Secondo il database Scopus, è tra i primi 10 medici al mondo per numero di pubblicazioni degli ultimi 2 anni nell’ambito “anesthesia”.

Ha partecipato, spesso in qualità di principal investigator, a 48 protocolli di ricerca randomizzati approvati dal Comitato Etico dell’Ospedale San Raffaele.

Da novembre 2018 è Membro del Comitato esperti per lo sviluppo del Sistema Sanitario Lombardo.

Membro del Gruppo di Lavoro HTA per valutare il device Impella 5.0 (produzione di Alert HTA per Regione Lombadia) dal 18 Luglio 2019.

Nel periodo 2009-2011 è stato Consulente del Ministro della Salute, Prof. Ferruccio Fazio e Membro del Comitato Scientifico del CCM (Centro Controllo Malattie Nazionali del Ministero della Salute).

E’ stato membro della Commissione Sport e Salute dal 2008 al 2011, della Commissione Paritetica di Programmazione Congiunta del Ministero della Salute ed Istruzione, Presidente della Commissione del Ministero della Salute per la Pandemia Influenzale dal 2009 al 2011 e Vice Presidente della Commissione Nazionale Ricerca Sanitaria.

Nel periodo 2008-2014 è stato membro della Commissione di Bioetica del Ministero della Salute.

Nel periodo 2011-2014 è stato presidente della II Commissione del Consiglio Superiore di Sanità.

Insignito del titolo di Cavaliere al merito della Repubblica Italiana dal Presidente della Repubblica Azeglio Ciampi, in data 2 Giugno 2004.

Insignito del titolo di Commendatore dal Presidente della Repubblica Italiana Giorgio Napolitano, in data 27 Dicembre 2010.

Attività di insegnamento

Docente per le Scuole di Specializzazione in Anestesia e Rianimazione, Chirurgia Vascolare, Chirurgia Toracica, Neurochirurgia, Chirurgia dell’Apparato Digerente e Malattie dell’Apparato Cardiovascolare.

Docente presso il Corso Post-Graduate di Chirurgia e protesi Odontostomatologica (direttore Prof. Gherlone) dell’Università Vita-Salute San Raffaele.

Docente nell’ ambito del corso elettivo sulle Moderne procedure di trattamento del paziente nel periodo perioperatorio per studenti del Corso di Laurea in Medicina e Chirurgia.

Attività didattica tutoriale agli specializzandi di Anestesia e Rianimazione e Cardiologia.

Attività didattica formativa professionalizzante (APRO) per studenti del Corso di Laurea in Medicina e Chirurgia.

Docente nell’ambito del Corso Integrato di Emergenze Medico Chirurgiche.

Docente nell’ambito del Corso Integrato di Infermieristica Clinica in Area Critica.

Ha svolto anche le seguenti attività di insegnamento

Docente nell’ambito del I° Corso Annuale Teorico Pratico di Ecocardiografia Transesofagea nel 2004.

Docente nell’ambito del Master di Eco-doppler in cardiochirurgia – Insufficienza Mitralica Degenerativa negli anni 2005/2006 e 2008.

Docente nell’ambito del Corso di Aggiornamento SIAARTI, La moderna Anestesia Bilanciata Anestesia Generale e Protezione a Giugno 2005.

Direttore e docente del Master di II Livello in Terapia Intensiva Cardiochirurgia, Università Vita-Salute Ospedale San Raffaele nel 2008/2009.

Direttore e docente del Master di I Livello in Assistenza Infermieristica Avanzata al Paziente Critico, Università Vita-Salute Ospedale San Raffaele negli anni 2010/2011, 2016/2017, 2017/2018.

Coordinatore e Docente nell’ambito del Corso Integrato sull’Assistenza avanzata al paziente critico con patologia cardiocircolatoria.

Coordinatore e Docente del Corso Integrato sull’Assistenza avanzata al paziente critico con patologia cardiocircolatoria negli anni 2007/2008, 2008/2009 e 2010/2011.

Coordinatore e Docente del Corso Integrato sull’Assistenza avanzata al paziente critico con patologie cardiologiche ad alta intensità assistenziale negli anni 2016/2017 e 2017/2018.

Direttore della Scuola di Anestesia e Rianimazione, Università   Vita-Salute San Raffaele di Milano fino a Ottobre 2017.

Co-Direttore programma di fellowship EACTA (European Association of Cardiothoracic Anaesthesiology).

Attività di ricerca in atto

Le principali linee di ricerca vertono sulla implementazione di supporti meccanici avanzati alle funzioni vitali (sistema cardiovascolare e respiratorio) e sulla riduzione della mortalità perioperatoria e del danno d’organo. Nello specifico:

- ECMO (ExtraCorporeal Membrane Oxygenation), VAD (Ventricular Assist Device), cuore artificiale e altri supporti meccanici avanzati al circolo sistemico per il trattamento dello scompenso cardiaco acuto;

-coordinamento di reti nazionale di centri di eccellenza sui supporti avanzati al circolo e alla ventilazione (ECMO, VAD, cuore artificiale, trattamento dello scompenso cardiaco acuto);

- ventilazione non invasiva (NIV) nel malato critico, sia in terapia intensiva che ai piani di degenza, incluso lo sviluppo di nuovi devices meccanici per la ventilazione non invasiva;

- ventilazione protettiva intraoperatoria con partecipazione a studi multicentrici per approfondire le modalità ventilatorie cui vengono sottoposti i pazienti durante anestesia generale in Europa e quali conseguenze il trattamento ventilatorio intraoperatorio abbia sul decorso e lo sviluppo di complicanze postoperatorie;

- ruolo di anticoagulanti alternativi nella gestione perioperatoria del paziente cardiochirurgico;

- ottimizzazione dell’emostasi perioperatoria con partecipazione a studi internazionali multicentrici, randomizzati negli interventi cardiovascolari complessi;

- ruolo degli anestetici alogenati nella cardioprotezione perioperatoria con studi randomizzati sul confronto tra anestetico alogenato e anestetico endovenoso nel danno miocardico perioperatorio dei pazienti ad alto rischio sottoposti a chirurgia cardiaca e non cardiaca;

- prevenzione della mortalità perioperatoria e dell'infarto miocardico acuto perioperatorio: ruolo di betabloccanti, inotropi, antiaggreganti e clonidina. In particolare partecipazione a studi internazionali come centro coordinatore nazionale italiano.

- prevenzione e trattamento dell'insufficienza renale acuta perioperatoria e del danno d'organo del paziente critico con coordinamento di studi randomizzati multicentrici;

- ruolo della metabolomica nell’identificazione di fenotipi metabolici differenti associati allo sviluppo di outcome specifici nei pazienti cardiochirurgici, affetti da patologia oncoematologica o sottoposti ad aneurismectomia dell’aorta toracoaddominale;

- ruolo dell’ecografia nello studio della funzionalità diaframmatica dopo aneurismectomia dell’aorta toracoaddominale

- cardiac biomarkers (proBNP, cardiac troponin) and renal biomarkers (ouabaine);

- sepsi in terapia intensiva;

- emergenze intra (medical emergency team) ed extra ospedaliere;

- management anestesiologico del paziente ad elevatissimo rischio periprocedurale (per esempio sottoposto a procedure di sostituzione valvolare percutanea);

- antibioticoterapia in terapia intensiva;

- controllo del dolore perioperatorio;

- coordinamento di un network internazionale tramite web-based consensus conferences;

Attività Clinico-Assistenziale

Dirigente Medico dal 1986.

Primario dell’Unità Operativa di Anestesia e Rianimazione Cardio-Toraco-Vascolare, IRCCS Ospedale San Raffaele dal 2003.

Primario dell’Unità Operativa di Terapia Intensiva e Rianimazione Generale, IRCCS Ospedale San Raffaele e dell’Unità Operativa di Anestesia e Rianimazione San Raffaele Turro dal 2008.

Finanziamenti/Grants

Vincitore Bando Ricerca Finalizzata 2018, come Principal Investigator, con il progetto “Acute normovolemic hemodilution in high-risk cardiac surgery patients. A multicenter randomized trial – ANH)”.

Vincitore Bando Fondazione Roche 2018, come Direttore/CO-Principal Investigator, per il progetto: “CIAO: Comunicare in autonomia”.

Vincitore bando Conto Capitale 2012 “Creazione di una ECMO-room”.

Vincitore Bando 2012 AIFA Ricerca Indipendente sui farmaci “Continuous infusion versus intermittent administration of MERopenem in CriticallY ill patients. A multicenter randomized double blind trial. – MERCY” (Multicentrico- Randomizzato – Farmacologico).

Vincitore bando Ricerca Indipendente della Regione Lombardia, anno 2010. “Attività di coordinamento e gestione domiciliare di pazienti portatori di dispositivi di assistenza ventricolare (VAD) per il trattamento dell’insufficienza cardiaca terminale: il VAD Coordinator”.

Vincitore bando Ricerca Finalizzata del Ministero della Salute, anno 2010.   “Volatile anesthetics to reduce mortality in cardiac surgery. A multicentre randomized controlled study. (Gli alogenati nel paziente cardiochirurgico. Uno studio multicentrico randomizzato controllato)”.

Vincitore bando ricerca Finalizzata del Ministero della Salute, anno 2009. “Levosimendan to reduce mortality in high risk cardiac surgery patients. A multicentre randomized controlled trial (Levosimendan in pazienti cardiochirurgici ad alto rischio. Uno studio multicentrico randomizzato controllato)”.

Responsabile Clinico del progetto finanziato dalla Regione Lombardia, anno 2009. “Utilizzo di sistemi di assistenza ventricolare sinistra a flusso continuo in pazienti affetti da insufficienza cardiaca terminale”.

Referente progetto CCM “Supporto extracorporeo cardiorespiratorio con ECMO (extracorporeal membrane oxygenation) in pazienti con scompenso cardiaco: miglioramento dell’outcome e prevenzione delle complicanze”. Anno 2009 – Prot. CNR-iBFM n. 00000175 del 14/04/2009.

Coordinatore Responsabile del Progetto stipulato il 26 novembre 2009 tra il Ministero della Salute, l’Azienda Ospedaliera San Gerardo di Monza e la Fondazione Centro San Raffaele del Monte Tabor per la realizzazione della: “Rete nazionale per la gestione della sindrome da insufficienza respiratoria acuta grave da polmoniti da virus A(H1N1) e l’eventuale utilizzo della terapia ECMO”.

Grant from the European Commission H2020 Programme, call H2020-ICT-2020-2, as co-applicant of the project “ARTERY - Autonomous Robotics for Transcatheter dEliveRy sYstems” (Local PI Prof Alberto Zangrillo, PI Prof. Emiliano Votta, Politecnico di Milano). Project ID: 101017140.

(Agg. mar. 2022)

Pubblicazioni

Pubblicazioni su riviste scientifiche indicizzate   2018-2022

D'Amico F, Marmiere M, Righetti B, Scquizzato T, Zangrillo A, Puglisi R, Landoni G. COVID-19 seasonality in temperate countries. Environ Res. 2022;206:112614

Novellis P, Monaco F, Landoni G, Rossetti F, Carretta A, Gregorc V, Zangrillo A, Veronesi G. Venoarterial Extracorporeal Membrane Oxygenator Support in Lung Cancer Resection. Ann Thorac Surg 2022;113:e191-e193

Belletti A, Todaro G, Valsecchi G, Losiggio R, Palumbo D, Landoni G, Zangrillo A. Barotrauma in Coronavirus Disease 2019 Patients Undergoing Invasive Mechanical Ventilation: A Systematic Literature Review. Crit Care Med. 2022;50:491-500

Ball L, Volta CA, Saglietti F, Spadaro S, Di Lullo A, De Simone G, Guarnieri M, Della Corte F, Serpa Neto A, Gama de Abreu M, Schultz MJ, Zangrillo A, Pelosi P, Bignami E.Associations Between Expiratory Flow Limitation and Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2022;36:815-824

Scquizzato T, Bonaccorso A, Consonni M, Scandroglio AM, Swol J, Landoni G, Zangrillo A. Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized and propensity score-matched studies. Artif Organs. 2022 Feb 23

Montorfano M, Leoni O, Andreassi A, Ludergnani M, Moroni F, Ancona MB, Landoni G, Ciceri F, Zangrillo A. Chronic anticoagulant treatment and risk of mortality in SARS-Cov2 patients: a large population-based study. Minerva Med. 2022 Feb 22

Pieri M, Vettorello F, Calabrò MG, Zangrillo A, Scandroglio AM. Trend and Pattern of 100 Acute Respiratory Distress Syndrome Patients Referred for Venovenous Extracorporeal Membrane Oxygenation Treatment in a National Referral Center in North Italy During the Last Decade.                  J Cardiothorac Vasc Anesth. 2022;36:529-533       

Compagnone N, Palumbo D, Cremona G, Vitali G, De Lorenzo R, Calvi MR, Del Prete A, Baiardo Redaelli M, Calamarà S, Belletti A, Steidler S, Conte C, Zangrillo A, De Cobelli F, Rovere-Querini P; COVID-BioB Study Group, Monti G. Residual lung damage following ARDS in COVID-19 ICU survivors. Acta Anaesthesiol Scand. 2022;66:223-231

Franchini S, Mette F, Landoni G, Setti E, Ferrante L, Calcaterra B, Pagliula G, Barbieri A, Fontani D, Borio G, Citro M, Farolfi F, Suma G, Monti G, Colombo S, Dagna L, Rovere-Querini P, DE Cobelli F, Castagna A, Ciceri F, Zangrillo A, Tresoldi M, Secchi A, Etteri M. Gas-exchange deficit and systemic hypoperfusion in COVID-19 and non-COVID-19 young adult patients with pneumonia. Panminerva Med. 2022 Feb 4

Zangrillo A, Lomivorotov VV, Pasyuga VV, Belletti A, Gazivoda G, Monaco F, Nigro Neto C, Likhvantsev VV, Bradic N, Lozovskiy A, Lei C, Bukamal NAR, Silva FS, Bautin AE, Ma J, Yong CY, Carollo C, Kunstyr J, Wang CY, Grigoryev EV, Riha H, Wang C, El-Tahan MR, Scandroglio AM, Mansor M, Lembo R, Ponomarev DN, Bezerra FJL, Ruggeri L, Chernyavskiy AM, Xu J, Tarasov DG, Navalesi P, Yavorovskiy A, Bove T, Kuzovlev A, Hajjar LA, Landoni G; MYRIAD Study Group. Effect of Volatile Anesthetics on Myocardial Infarction After Coronary Artery Surgery: A Post Hoc Analysis of a Randomized Trial. J Cardiothorac Vasc Anesth. 2022 Jan 7

Bravi CA, Cazzaniga W, Simonini M, Larcher A, Messaggio E, Zagato L, Carenzi C, Bertini R, Briganti A, Manunta P, Vezzoli G, Salonia A, Lanzani C, Capitanio U, Zangrillo A, Landoni G, Rovere-Querini P, Tresoldi M, Montorsi F, Ciceri F. Acute Kidney Injury at Hospital Admission for SARS-CoV-2 Infection as a Marker of Poor Prognosis: Clinical Implications for Triage Risk Stratification. Kidney Blood Press Res. 2022;47:147-150

Melillo F, Napolano A, Loffi M, Regazzoni V, Boccellino A, Danzi GB, Cappelletti AM, Rovere-Querini P, Landoni G, Ingallina G, Stella S, Ancona F, Dagna L, Scarpellini P, Ripa M, Castagna A, Tresoldi M, Zangrillo A, Ciceri F, Agricola E. Myocardial injury in patients with SARS-CoV-2 pneumonia: pivotal role of inflammation in COVID-19. Eur J Clin Invest. 2022;52:e13703

COVIDSurg Collaborative; GlobalSurg Collaborative.
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022;77:28-39

Salonia A, Pontillo M, Capogrosso P, Gregori S, Carenzi C, Ferrara AM, Rowe I, Boeri L, Larcher A, Ramirez GA, Tresoldi C, Locatelli M, Cavalli G, Dagna L, Castagna A, Zangrillo A, Tresoldi M, Landoni G, Rovere-Querini P, Ciceri F, Montorsi F. Testosterone in males with COVID-19: A seven-month cohort study. Andrology. 2022;10:34-41  

Bodega F, Russi A, Melillo F, Blunda F, Rubino C, Leo G, Cappelletti A, Mazzone P, Mattiello P, Bella PD, Castiglioni A, Alfieri O, De Bonis M, Montorfano M, Tresoldi M, Filippi M, Salerno A, Cera M, Zangrillo A, Alberto M, Godino C; INSigHT (Italian DOACs San Raffaele Hospital) registry investigators. Direct Oral Anticoagulants in Patients with Non-valvular Atrial Fibrillation and Extreme Body Weight. Eur J Clin Invest. 2022;52:e13658        

Negro A, Villa G, Zangrillo A, Rosa D, Manara DF. Diaries in intensive care units: An Italian qualitative study. Nurs Crit Care. 2022;27:36-44      

Nini A, Muttin F, Cianflone F, Carenzi C, Lucianó R, Catena M, Larcher A, Salvioni M, Cazzaniga W, Pederzoli F, Matloob R, Colombo R, Paganelli M, Salonia A, Briganti A, Doglioni C,       Zangrillo A, De Cobelli F, Rigatti P, Freschi M, Cornero G, Nicoletti R, Aldrighetti L, Montorsi F, Capitanio U, Bertini R. Perioperative and oncologic outcomes of open radical nephrectomy and inferior vena cava thrombectomy with liver mobilization and Pringle maneuver for Mayo III level tumor thrombus: single institution experience. Minerva Urol Nefrol. 2021;73:746-753

Zangrillo A, Belletti A, Palumbo D, Calvi MR, Guzzo F, Fominskiy EV, Ortalda A, Nardelli P, Ripa M, Baiardo Redaelli M, Borghi G, Landoni G, D'Amico F, Marmiere M, Righetti B, Rocchi M, Saracino M, Tresoldi M, Dagna L, De Cobelli F; COVID-BioB Study Group. One-Year Multidisciplinary Follow-Up of Patients With COVID-19 Requiring Invasive Mechanical Ventilation. J Cardiothorac Vasc Anesth. 2021 Nov 27

Scquizzato T, Young PJ, Landoni G, Zaraca L, Zangrillo A. Randomised trials of temperature management in cardiac arrest: Are we observing the Zeno's paradox of the Tortoise and Achilles? Crit Care. 2021;25:409     

Bossi E, Gianfredi V, Odone A, Valsecchi D, Franchini S, Etteri M, Cornero G, Casiraghi GM, Maimeri N, Beccaria PF, Moizo E, Mucci M, Silvani P, Plumari VP, Borghi G, Pasculli N, La Bruna A, Baiardo Redaelli M, Dell'Acqua A, Azzolini ML, Guzzo F, Alba AC, Sordoni S, Tozzi M, Nisi FG, Fresilli S, Zangrillo A, Signorelli C. COVID-19 second wave: appropriateness of admissions to the Emergency Department of a main metropolitan hospital in Milan. Acta Biomed. 2021;92:e2021419

Scquizzato T, Landoni G, Bordoni G, Zaraca L, Monti G, Zangrillo A. AED training with a 3D-printed model and a smartphone app. Resuscitation. 2021;169:95-96      

Belletti A, Campochiaro C, Marmiere M, Likhvantsev V, Yavorovskiy A, Dagna L, Landoni G, Zangrillo A, Hajjar LA. Efficacy and safety of IL-6 inhibitors in patients with COVID-19 pneumonia: a systematic review and meta-analysis of multicentre, randomized trials. Ann Intensive Care. 2021;11:152

Consolo F, Marasi A, Della Valle P, Bonora M, Pieri M, Scandroglio AM, Redaelli A, Zangrillo A, D'Angelo A, Pappalardo F. Bleeding in patients with continuous-flow left ventricular assist devices: acquired von Willebrand disease or antithrombotics? Eur J Cardiothorac Surg. 2021 Oct 31
 

Scquizzato T, Landoni G, Scandroglio AM, Franco A, Calabrò MG, Paoli A, D'Amico F, Yavorovskiy A, Zangrillo A. Outcomes of out-of-hospital cardiac arrest in patients with SARS-CoV-2 infection: a systematic review and meta-analysis. Eur J Emerg Med. 2021;28:423-431

Pieri M, Donatelli V, Calabrò MG, Scandroglio AM, Pappalardo F, Zangrillo A. Eleven Years of Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: From H1N1 to SARS-CoV-2. Experience and Perspectives of a National Referral Center. J Cardiothorac Vasc Anesth. 2021 Sep 24      

Negro A, Villa G, Greco M, Ciriolo E, Luraschi EL, Scaramuzzi J, Manara DF, Zangrillo A. Thirst in patients admitted to intensive care units: an observational study. Ir J Med Sci. 2021 Oct 19:1-7

Yacoub MR, Cucca V, Asperti C, Ramirez GA, Della-Torre E, Moro M, Zandalasini C, Di Napoli D, Ambrosio A, Signorelli C, Colombo S, Beretta L, Ciceri F, Zangrillo A, Dagna L. Efficacy of a rational algorithm to assess allergy risk in patients receiving the BNT162b2 vaccine. Vaccine. 2021;39:6464-6469

Damanti S, Cristel G, Ramirez GA, Bozzolo EP, Da Prat V, Gobbi A, Centurioni C, Di Gaeta E, Del Prete A, Calabrò MG, Calvi MR, Borghi G, Zangrillo A, De Cobelli F, Landoni G, Tresoldi M. Influence of reduced muscle mass and quality on ventilator weaning and complications during intensive care unit stay in COVID-19 patients. Clin Nutr. 2021:S0261-5614(21)00375-7


COVIDSurg Collaborative; GlobalSurg Collaborative. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021; 76:1454-1464

Palumbo D, Zangrillo A, Belletti A, Guazzarotti G, Calvi MR, Guzzo F, Pennella R, Monti G, Gritti C, Marmiere M, Rocchi M, Colombo S, Valsecchi D, Scandroglio AM, Dagna L, Rovere-Querini P, Tresoldi M, Landoni G, De Cobelli F; COVID-BioB Study Group. A radiological predictor for pneumomediastinum/pneumothorax in COVID-19 ARDS patients. J Crit Care. 2021;66:14-19

Scquizzato T, D'Amico F, Rocchi M, Saracino M, Stella F, Landoni G, Zangrillo A. Impact of COVID-19 pandemic on out-of-hospital cardiac arrest system-of-care: A systematic review and meta-analysis. Prehosp Emerg Care. 2021 Sep 14:1-12      

Belletti A, Landoni G, Zangrillo A. Pneumothorax and barotrauma in invasively ventilated patients with COVID-19. Respir Med. 2021;187:106552           
 

Moizo E, Zangrillo A, Colombo S, Leggieri C, Mucci M, Beccaria P, Pasculli N, Borghi G, Plumari VP, La Bruna A, Dossi R, Redaelli MB, Tornaghi A, Lombardi G, Landoni G, Dell'Acqua A, Guzzo F, Monti G. Percutaneous tracheostomy in COVID-19 patients: a new apneic approach. Braz J Anesthesiol. 2021 Jul 27  
 

Sorbello S, Bossi E, Zandalasini C, Carioli G, Signorelli C, Ciceri F, Ambrosio A, Zangrillo A, Odone A. After Action Reviews of COVID-19 response: Case study of a large tertiary care hospital in Italy. Int J Health Plann Manage. 2021;36:1758-1771           

Monti G, Campochiaro C, Zangrillo A, Scandroglio AM, Fominskiy E, Cavalli G, Landoni G, Beretta L, Mucci M, Calabró MG, Pieri M, Nardelli P, Sartorelli M, Baiardo Redaelli M, Morselli F, Serpa Neto A, Bellomo R, Dagna L; COVID-BioB Study Group. Immunosuppressive strategies in invasively ventilated ARDS COVID-19 patients. Minerva Anestesiol. 2021;87:891-902

Negro A, Bambi S, De Vecchi M, Isotti P, Villa G, Miconi L, Dossi M, Ponzetta G, Rinaldi L, Radaelli C, Caballo C, Leggieri C, Colombo S, Cabrini L, Manara DF, Zangrillo A. The ABCDE bundle implementation in an intensive care unit: Facilitators and barriers perceived by nurses and doctors. Int J Nurs Pract. 2021 Jun 8:e12984

Gulletta S, Della Bella P, Pannone L, Falasconi G, Cianfanelli L, Altizio S, Cinel E, Da Prat V, Napolano A, D'Angelo G, Brugliera L, Agricola E, Landoni G, Tresoldi M, Rovere PQ, Ciceri F, Zangrillo A, Vergara P. QTc interval prolongation, inflammation, and mortality in patients with COVID-19. J Interv Card Electrophysiol. 2021 Jul 22:1-8      

Ramirez GA, Calvisi SL, DE Lorenzo R, DA Prat V, Borio G, Gallina G, Farolfi F, Cavallo L, Pascali M, Castellani J, Baccellieri D, Guzzo F, Baiardo Redaelli M, Azzolini ML, Alba AC, Zangrillo A, Bozzolo EP, Scotti R, DI Lucca G, Piemonti L, Rovere Querini P, D'Angelo A, Tresoldi M; COVID-BioB group. A novel evidence-based algorithm to predict thromboembolism in patients with COVID-19: preliminary data from a single-centre cohort. Minerva Med. 2021 Jun 11

Rubino C, Blunda F, Bodega F, Melillo F, Russi A, Mattiello P, Salerno A, Cera M, Margonato D, Mazzone P, Della Bella P, Castiglioni A, Alfieri O, DE Bonis M, Montorfano M, Filippi M, Tresoldi M, Cappelletti A, Zangrillo A, Margonato A, Godino C; INSigHT (Italian DOACs San Raffaele Hospital) registry investigators. Safety and efficacy of Direct Oral Anticoagulants (DOACs) in very elderly patients (≥ 85 years old) with non-valvular atrial fibrillation. The Experience of an Italian tertiary care center. Minerva Med. 2021 Jun 28

Apruzzi L, Altizio S, Loschi D, Bertoglio L, Peña A, Ajello S, Zangrillo A, Scandroglio AM. Intravascular Ultrasound Imaging and Endovascular Treatment of Left Ventricle Assist Device (HM3) Outflow Graft Obstruction. JACC Cardiovasc Interv. 2021;14:1497-1499

Conte C, Esposito A, De Lorenzo R, Di Filippo L, Palmisano A, Vignale D, Leone R, Nicoletti V, Ruggeri A, Gallone G, Secchi A, Bosi E, Tresoldi M, Castagna A, Landoni G, Zangrillo A, De Cobelli F, Ciceri F, Camici P, Rovere-Querini P. Epicardial adipose tissue characteristics, obesity and clinical outcomes in COVID-19: A post-hoc analysis of a prospective cohort study. Nutr Metab Cardiovasc Dis. 2021;31:2156-2164

Spagnuolo V, Guffanti M, Galli L, Poli A, Querini PR, Ripa M, Clementi M, Scarpellini P, Lazzarin A, Tresoldi M, Dagna L, Zangrillo A, Ciceri F, Castagna A; COVID-BioB study group. Publisher Correction: Viral clearance after early corticosteroid treatment in patients with moderate or severe covid-19. Sci Rep. 2021;11:10699

Marmiere M, D'Amico F, Zangrillo A, Landoni G. The 5 Reasons Why People Die of Coronavirus Disease 2019. J Cardiothorac Vasc Anesth. 2021;35:3454-3455

Zangrillo A, Landoni G, Monti G, Yavorovskiy AG, Baiardo Redaelli M. Dexamethasone in COVID-19: does one drug fits all? Med Intensiva. 2021 Apr 19

Esposito A, Palmisano A, Cao R, Rancoita P, Landoni G, Grippaldi D, Boccia E, Cosenza M, Messina A, La Marca S, Palumbo D, Di Serio C, Spessot M, Tresoldi M, Scarpellini P, Ciceri F, Zangrillo A, De Cobelli F. Quantitative assessment of lung involvement on chest CT at admission: Impact on hypoxia and outcome in COVID-19 patients. Clin Imaging. 2021;77:194-201

Della-Torre E, Lanzillotta M, Campochiaro C, Cavalli G, De Luca G, Tomelleri A, Boffini N, De Lorenzo R, Ruggeri A, Rovere-Querini P, Castagna A, Landoni G, Tresoldi M, Ciceri F,         Zangrillo A, Dagna L. Respiratory Impairment Predicts Response to IL-1 and IL-6 Blockade in COVID-19 Patients With Severe Pneumonia and Hyper-Inflammation. Front Immunol. 2021;12:675678

Mazzinari G, Serpa Neto A, Hemmes SNT, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Pearse RM, Putensen C, Schmid W, Severgnini P, Wrigge H, Cambronero OD, Ball L, de Abreu MG, Pelosi P, Schultz MJ; LAS VEGAS study–investigators; PROtective VEntilation NETwork; Clinical Trial Network of the European Society of Anaesthesiology. The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients - a posthoc propensity score-weighted cohort analysis of the LAS VEGAS study. BMC Anesthesiol. 2021;21:84

Cavalli G, Larcher A, Tomelleri A, Campochiaro C, Della-Torre E, De Luca G, Farina N, Boffini N, Ruggeri A, Poli A, Scarpellini P, Rovere-Querini P, Tresoldi M, Salonia A, Montorsi F, Landoni G, Castagna A, Ciceri F, Zangrillo A, Dagna L. Interleukin-1 and interleukin-6 inhibition compared with standard management in patients with COVID-19 and hyperinflammation: a cohort study. Lancet Rheumatol. 2021;3:e253-e261

De Simone F, Nardelli P, Licheri M, Frau G, Redaelli MB, Monaco F, Zangrillo A, Landoni G. Less is more: We are administering too much protamine in cardiac surgery. Ann Card Anaesth. 2021;24:178-182

COVIDSurg Collaborative; GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021;76:748-758

Palumbo D, Campochiaro C, Belletti A, Marinosci A, Dagna L, Zangrillo A, De Cobelli F; COVID-BioB Study Group. Pneumothorax/pneumomediastinum in non-intubated COVID-19 patients: Differences between first and second Italian pandemic wave. Eur J Intern Med. 2021;88:144-146

Monaco F, Barucco G, Licheri M, Mattioli C, Ortalda A, Lombardi G, Pallanch O, De Luca M, Chiesa R, Melissano G, Zangrillo A. Trigger and Target for Fibrinogen Supplementation Using Thromboelastometry (ROTEM) in Patients Undergoing Open Thoraco-Abdominal Aortic Aneurysm Repair. Eur J Vasc Endovasc Surg. 2021;61:799-808

COVIDSurg Collaborative, GlobalSurg Collaborative. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021;108:1056-1063

Belletti A, Palumbo D, Zangrillo A, Fominskiy EV, Franchini S, Dell'Acqua A, Marinosci A, Monti G, Vitali G, Colombo S, Guazzarotti G, Lembo R, Maimeri N, Faustini C, Pennella R, Mushtaq J, Landoni G, Scandroglio AM, Dagna L, De Cobelli F; COVID-BioB Study Group. Predictors of Pneumothorax/Pneumomediastinum in Mechanically Ventilated COVID-19 Patients. J Cardiothorac Vasc Anesth. 2021;35:3642-3651

Nijbroek SG, Hol L, Swart P, Hemmes SNT, Serpa Neto A, Binnekade JM, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ; LAS VEGAS study investigators, the PROVE Network and the Clinical Trial Network of the European Society of Anaesthesiology. Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study. Eur J Anaesthesiol. 2021; 38:1034-1041

Monti G, Leggieri C, Fominskiy E, Scandroglio AM, Colombo S, Tozzi M, Moizo E, Mucci M, Crivellari M, Pieri M, Guzzo F, Piemontese S, De Lorenzo R, Da Prat V, Fedrizzi M, Faustini C, Di Piazza M, Conte F, Lembo R, Esposito A, Dagna L, Landoni G, Zangrillo A. Two months quality of life of COVID-19 invasively ventilated survivors; an Italian single-center study. Acta Anaesthesiol Scand. 2021;65:912-920

Monti G, Galbiati C, Toffoletto F, Calabrò MG, Colombo S, Ferrara B, Giardina G, Lembo R, Marzaroli M, Moizo E, Mucci M, Pasculli N, Plumari V, Scandroglio AM, Tozzi M, Momesso E, Boffa N, Lobreglio R, Montrucchio G, Guarracino F, Benedetto U, Biondi-Zoccai G, D'Ascenzo F, D'Andrea N, Paternoster G, Ananiadou S, Ballestra M, De Sio A, Pota V, Cotoia A, Selva AD, Bruni A, Iapichino G, Bradić N, Corradi F, Gemma M, Nogtev P, Petrova M, Agrò FE, Cabrini L, Forfori F, Likhvantsev V, Bove T, Finco G, Landoni G, Zangrillo A; Collaborators. Continuous infusion versus intermittent administration of meropenem in critically ill patients (MERCY): A multicenter randomized double-blind trial. Rationale and design. Contemp Clin Trials. 2021;104:106346

Ancona MB, Moroni F, Romano V, Agricola E, Esposito A, Ajello S, De Bonis M, Cappelletti AM, Zangrillo A, Scandroglio AM, Montorfano M.  [Transcatheter aortic valve implantation for aortic regurgitation in patients with left ventricular assist device]. G Ital Cardiol (Rome). 2021;22:39S-42S

Shehabi Y, Serpa Neto A, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Kadiman SB, McArthur CJ, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; SPICE III Study Investigators. Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial. Intensive Care Med. 2021;47:455-466

Salonia A, Pontillo M, Capogrosso P, Gregori S, Tassara M, Boeri L, Carenzi C, Abbate C, Cignoli D, Maria Ferrara A, Cazzaniga W, Rowe I, Ramirez GA, Tresoldi C, Mushtaq J, Locatelli M, Santoleri L, Castagna A, Zangrillo A, De Cobelli F, Tresoldi M, Landoni G, Rovere-Querini P, Ciceri F, Montorsi F. Severely low testosterone in males with COVID-19: a case-control study. Andrology. 2021;9:1043-1052

Pasin L, Cavalli G, Navalesi P, Sella N, Landoni G, Yavorovskiy AG, Likhvantsev VV,          Zangrillo A, Dagna L, Monti G. Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies. Eur J Intern Med. 2021;86:34-40

Monaco F, Ajello S, Calabrò MG, Melisurgo G, Landoni G, Arata A, Lerose CC, Fumagalli E, Tomasso ND, Frontera A, Scandroglio AM, Della Bella P, Zangrillo A. Left Ventricular Unloading With an IABP in Patients Undergoing Ventricular Tachycardia Ablation With ECMO Support.             J Cardiothorac Vasc Anesth. 2021;35:2686-2693

Lorusso R, Combes A, Coco VL, De Piero ME, Belohlavek J; EuroECMO COVID-19 WorkingGroup; Euro-ELSO Steering Committee. ECMO for COVID-19 patients in Europe and Israel. Intensive Care Med. 2021:47:344-348

Zangrillo A, Bignami E, Noè B, Nardelli P, Licheri M, Gerli C, Crivellari M, Oriani A, Di Prima AL, Fominskiy E, Di Tomasso N, Lembo R, Landoni G, Crescenzi G, Monaco F. Esmolol in Cardiac Surgery: A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. 2021;35:1106-1114

De Cobelli F, Palumbo D, Ciceri F, Landoni G, Ruggeri A, Rovere-Querini P, D'Angelo A, Steidler S, Galli L, Poli A, Fominskiy E, Calabrò MG, Colombo S, Monti G, Nicoletti R, Esposito A, Conte C, Dagna L, Ambrosio A, Scarpellini P, Ripa M, Spessot M, Carlucci M, Montorfano M, Agricola E, Baccellieri D, Bosi E, Tresoldi M, Castagna A, Martino G, Zangrillo A. Pulmonary Vascular Thrombosis in COVID-19 Pneumonia. J Cardiothorac Vasc Anesth. 2021;35:3631-3641

Di Tomasso N, Lerose CC, Licheri M, Castro LEA, Tamà S, Vitiello C, Landoni G, Zangrillo A, Monaco F. Dynamic arterial elastance measured with pressure recording analytical method, and mean arterial pressure responsiveness in hypotensive preload dependent patients undergoing cardiac surgery: A prospective cohort study. Eur J Anaesthesiol. 2021;38:402-410

Mancini N, Clementi N, Ferrarese R, Ambrosi A, Tonelli M, Zangrillo A, Landoni G, Clementi M.Very high SARS-CoV-2 load at the emergency department presentation strongly predicts the risk of admission to the intensive care unit and death. Clin Chem Lab Med. 2021; 59:e247-e250

Baiardo Redaelli M, Landoni G, Di Napoli D, Morselli F, Sartorelli M, Sartini C, Ruggeri A, Salonia A, Dagna L, Zangrillo A. Novel Coronavirus Disease (COVID-19) in Italian Patients: Gender Differences in Presentation and Severity. Saudi J Med Med Sci. 2021;9:59-62

Esposito A, Palmisano A, Toselli M, Vignale D, Cereda A, Rancoita PMV, Leone R, Nicoletti V, Gnasso C, Monello A, Biagi A, Turchio P, Landoni G, Gallone G, Monti G, Casella G, Iannopollo G, Nannini T, Patelli G, Di Mare L, Loffi M, Sergio P, Ippolito D, Sironi S, Pontone G, Andreini D, Mancini EM, Di Serio C, De Cobelli F, Ciceri F, Zangrillo A, Colombo A, Tacchetti C, Giannini F. Chest CT-derived pulmonary artery enlargement at the admission predicts overall survival in COVID-19 patients: insight from 1461 consecutive patients in Italy. Eur Radiol. 2021;31:4031-4041

Landoni G, Maimeri N, Fedrizzi M, Fresilli S, Kuzovlev A, Likhvantsev V, Nardelli P, Zangrillo A. Why are Asian countries outperforming the Western world in controlling COVID-19 pandemic? Pathog Glob Health. 2021;115:70-72

Mastrangelo A, Germinario BN, Ferrante M, Frangi C, Li Voti R, Muccini C, Ripa M; COVID-BioB Study Group. Candidemia in COVID-19 patients: incidence and characteristics in a prospective cohort compared to historical non-COVID-19 controls. Clin Infect Dis. 2021;73:e2838-e2839

Ripa M, Galli L, Poli A, Oltolini C, Spagnuolo V, Mastrangelo A, Muccini C, Monti G, De Luca G, Landoni G, Dagna L, Clementi M, Rovere Querini P, Ciceri F, Tresoldi M, Lazzarin A, Zangrillo A, Scarpellini P, Castagna A; COVID-BioB study group. Secondary infections in patients hospitalized with COVID-19: incidence and predictive factors. Clin Microbiol Infect. 2021;27:451-457

Zangrillo A, Morselli F, Lombardi G, Yavorovskiy A, Likhvantsev V, Beretta L, Monaco F, Landoni G. Procedural sedation and analgesia for percutaneous high tech cardiac procedures. Minerva Cardioangiol. 2021;69:358-369

Mushtaq J, Pennella R, Lavalle S, Colarieti A, Steidler S, Martinenghi CMA, Palumbo D, Esposito A, Rovere-Querini P, Tresoldi M, Landoni G, Ciceri F, Zangrillo A, De Cobelli F. Initial chest radiographs and artificial intelligence (AI) predict clinical outcomes in COVID-19 patients: analysis of 697 Italian patients. Eur Radiol. 2021;31:1770-1779

Belletti A, Lerose CC, Zangrillo A, Landoni G. Vasoactive-Inotropic Score: Evolution, Clinical Utility, and Pitfalls. J Cardiothorac Vasc Anesth. 2021;35:3067-3077

Fominskiy EV, Scandroglio AM, Monti G, Calabrò MG, Landoni G, Dell'Acqua A, Beretta L, Moizo E, Ravizza A, Monaco F, Campochiaro C, Pieri M, Azzolini ML, Borghi G, Crivellari M, Conte C, Mattioli C, Silvani P, Mucci M, Turi S, Tentori S, Baiardo Redaelli M, Sartorelli M, Angelillo P, Belletti A, Nardelli P, Nisi FG, Valsecchi G, Barberio C, Ciceri F, Serpa Neto A, Dagna L, Bellomo R, Zangrillo A; COVID-BioB Study Group. Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy. Blood Purif. 2021;50:102-109

Kim JH, Pieri M, Landoni G, Scandroglio AM, Calabrò MG, Fominskiy E, Lembo R, Heo MH, Zangrillo A. Venovenous ECMO treatment, outcomes, and complications in adults according to large case series: A systematic review. Int J Artif Organs. 2021;44:481-488

Renzi S, Clementi M, Racca S, Mucci M, Beccaria P, Borghi G, Landoni G, Zangrillo A. Is Bordetella pertussis co-infecting SARS-CoV-2 patients? Braz J Anesthesiol. 2021;71:92-93Pasin L, Navalesi P, Zangrillo A, Kuzovlev A, Likhvantsev V, Hajjar LA, Fresilli S, Lacerda MVG, Landoni G. Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials. J Cardiothorac Vasc Anesth. 2021;35:578-584

Baccellieri D, Bertoglio L, Apruzzi L, Ardita V, D'Angelo A, Bossi M, Rinaldi E, Bilman V, Calvisi S, Castagna A, Galli L, Landoni G, Melissano G, Querini PR, Tresoldi M, De Cobelli F, Zangrillo A, Ciceri F, Chiesa R. Incidence of deep venous thrombosis in COVID-19 hospitalized patients during the first peak of the Italian outbreak. Phlebology. 2021;36:375-383

Franchini S, Spessot M, Landoni G, Piani C, Cappelletti C, Mariani F, Mauri S, Taglietti MV, Fortunato M, Furlan F, Guglielmi B, Setti E, Di Napoli D, Borghi G, Pascucci F, Sannicandro R, Moro M, Colombo S, Dagna L, Castagna A, Tresoldi M, Rovere-Querini P, Ambrosio A, Ciceri F, Zangrillo A, Carlucci M, Faccincani R. Stranger months: how SARS-CoV-2, fear of contagion, and lockdown measures impacted attendance and clinical activity during February and March 2020 at an urban Emergency Department in Milan. Disaster Med Public Health Prep. 2021;15:e33-e42

Carugo S, Ferlini M, Castini D, Andreassi A, Guagliumi G, Metra M, Lombardi C, Cuccia C, Savonitto S, Piatti L, D'Urbano M, Lettieri C, Vandoni P, Lettino M, Marenzi G, Montorfano M, Zangrillo A, Castiglioni B, De Ponti R, Oltrona Visconti L. Management of acute coronary syndromes during the COVID-19 outbreak in Lombardy: The "macro-hub" experience. Int J Cardiol Heart Vasc. 2020 Dec;31:100662

Spagnuolo V, Guffanti M, Galli L, Poli A, Querini PR, Ripa M, Clementi M, Scarpellini P, Lazzarin A, Tresoldi M, Dagna L, Zangrillo A, Ciceri F, Castagna A; COVID-BioB study group. Viral clearance after early corticosteroid treatment in patients with moderate or severe covid-19. Sci Rep. 2020;10:21291

Foti G, Giannini A, Bottino N, Castelli GP, Cecconi M, Grasselli G, Guatteri L, Latronico N, Langer T, Monti G, Muttini S, Pesenti A, Radrizzani D, Ranucci M, Russotto V, Fumagalli R; COVID-19 Lombardy ICU Network. Management of critically ill patients with COVID-19: suggestions and instructions from the coordination of intensive care units of Lombardy. Minerva Anestesiol. 2020;86:1234-1245

Scquizzato T, Landoni G, Paoli A, Lembo R, Fominskiy E, Kuzovlev A, Likhvantsev V,        Zangrillo A. Effects of COVID-19 pandemic on out-of-hospital cardiac arrests: A systematic review. Resuscitation. 2020;157:241-247

Rovere-Querini P, Tresoldi C, Conte C, Ruggeri A, Ghezzi S, De Lorenzo R, Di Filippo L, Farina N, Ramirez GA, Ripa M, Mancini N, Cantarelli E, Galli L, Poli A, De Cobelli F, Bonini C, Manfredi AA, Franchini S, Spessot M, Carlucci M, Dagna L, Scarpellini P, Ambrosio A, Di Napoli D, Bosi E, Tresoldi M, Lazzarin A, Landoni G, Martino G, Zangrillo A, Poli G, Castagna A, Vicenzi E, Clementi M, Ciceri F; COVID-BioB Study Group. Biobanking for COVID-19 research. Panminerva Med. 2020 Oct 19

Ramirez GA, Bozzolo EP, Castelli E, Marinosci A, Angelillo P, Damanti S, Scotti R, Gobbi A, Centurioni C, Di Scala F, Morgillo A, Castagna A, Conte C, Assanelli A, De Cobelli F, Calcaterra B, Cabrini L, Carcó F, Turi S, Silvani P, Dagna L, Zangrillo A, Landoni G, Tresoldi M; Covid-19 BioB Study Group. Continuous positive airway pressure and pronation outside the intensive care unit in COVID 19 ARDS. Minerva Med. 2020 Sep 30

De Lorenzo R, Conte C, Lanzani C, Benedetti F, Roveri L, Mazza MG, Brioni E, Giacalone G, Canti V, Sofia V, D'Amico M, Di Napoli D, Ambrosio A, Scarpellini P, Castagna A, Landoni G, Zangrillo A, Bosi E, Tresoldi M, Ciceri F, Rovere-Querini P. Residual clinical damage after COVID-19: A retrospective and prospective observational cohort study. PLoS One. 2020;15:e0239570

Secchi M, Bazzigaluppi E, Brigatti C, Marzinotto I, Tresoldi C, Rovere-Querini P, Poli A, Castagna A, Scarlatti G, Zangrillo A, Ciceri F, Piemonti L, Lampasona V. COVID-19 survival associates with the immunoglobulin response to the SARS-CoV-2 spike Receptor Binding Domain. J Clin Invest. 2020;130:6366-6378

Renzi S, Landoni G, Zangrillo A, Ciceri F. MicroCLOTS pathophysiology in COVID 19. Korean J Intern Med. 2020 Sep 9

Della-Torre E, Campochiaro C, Cavalli G, De Luca G, Napolitano A, La Marca S, Boffini N, Da Prat V, Di Terlizzi G, Lanzillotta M, Rovere Querini P, Ruggeri A, Landoni G, Tresoldi M, Ciceri F, Zangrillo A, De Cobelli F, Dagna L; SARI-RAF Study Group; SARI-RAF Study Group members. Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study. Ann Rheum Dis. 2020; 79:1277-1285

Della-Torre E, Campochiaro C, Cavalli G, De Luca G, Ciceri F, Zangrillo A, Dagna L.Targeting IL-1, IL-6 or GM-CSF in COVID-19. Response to: 'More evidences on which biologic and which pathway is key in severe-critical COVID-19 pneumonia' by Ferraccioli. Ann Rheum Dis. 2020 Jul 31

Sala S, Peretto G, De Luca G, Farina N, Campochiaro C, Tresoldi M, Dagna L, Zangrillo A, Gulletta S, Della Bella P. Low prevalence of arrhythmias in clinically stable COVID-19 patients. Pacing Clin Electrophysiol. 2020;43:891-893

Agricola E, Beneduce A, Esposito A, Ingallina G, Palumbo D, Palmisano A, Ancona F, Baldetti L, Pagnesi M, Melisurgo G, Zangrillo A, De Cobelli F. Heart and Lung Multimodality Imaging in COVID-19. JACC Cardiovasc Imaging. 2020;13:1792-1808

Godino C, Bodega F, Melillo F, Rubino F, Parlati ALM, Cappelletti A, Mazzone P, Mattiello P, Della Bella P, Castiglioni A, Alfieri O, De Bonis M, Montorfano M, Tresoldi M, Filippi M, Zangrillo A, Salerno A, Cera M, Margonato A; INSIgHT (Italian NOACs San Raffaele Hospital) registry investigators. Inappropriate dose of nonvitamin-K antagonist oral anticoagulants: prevalence and impact on clinical outcome in patients with nonvalvular atrial fibrillation. J Cardiovasc Med (Hagerstown). 2020;21:751-758

Landoni G, Moro M, Belletti A, Rovere-Querini P, Veronesi G, Ruggeri A, Lembo R, Dalessandro G, Galbiati C, Serpa Neto A, Zangrillo A. Recent exposure to smoking and COVID-19. Crit Care Resusc. 2020;22:253-256

Ciceri F, Castagna A, Rovere-Querini P, De Cobelli F, Ruggeri A, Galli L, Conte C, De Lorenzo R, Poli A, Ambrosio A, Signorelli C, Bossi E, Fazio M, Tresoldi C, Colombo S, Monti G, Fominskiy E, Franchini S, Spessot M, Martinenghi C, Carlucci M, Beretta L, Scandroglio AM, Clementi M, Locatelli M, Tresoldi M, Scarpellini P, Martino G, Bosi E, Dagna L, Lazzarin A, Landoni G, Zangrillo A. Early predictors of clinical outcomes of COVID-19 outbreak in Milan, Italy. Clin Immunol. 2020;217:108509

Cecchetti G, Vabanesi M, Chieffo R, Fanelli G, Minicucci F, Agosta F, Tresoldi M, Zangrillo A, Filippi M. Cerebral involvement in COVID-19 is associated with metabolic and coagulation derangements: an EEG study. J Neurol. 2020;267:3130-3134

Cavalli G, Landoni G, Zangrillo A, Dagna L. Anakinra for patients with COVID-19 – Authors' reply. The Lancet Rheumatology 2020;2:e383-e384

Landoni G, Losi D, Fresilli S, Lazzari S, Nardelli P, Puglisi R, Zangrillo A. Is time our ultimate ally in defying the pandemic? Pathog Glob Health. 2020;114:279-280

Di Filippo L, Formenti AM, Rovere-Querini P, Carlucci M, Conte C, Ciceri F, Zangrillo A, Giustina A. Hypocalcemia is highly prevalent and predicts hospitalization in patients with COVID-19. Endocrine. 2020;68:475-478

Ciceri F, Ruggeri A, Lembo R, Puglisi R, Landoni G, Zangrillo A; COVID-BioB Study Group. Decreased in-hospital mortality in patients with COVID-19 pneumonia. Pathog Glob Health. 2020;114:281-282

Scquizzato T, Pallanch O, Belletti A, Frontera A, Cabrini L, Zangrillo A, Landoni G. Enhancing citizens response to out-of-hospital cardiac arrest: A systematic review of mobile-phone systems to alert citizens as first responders. Resuscitation. 2020;152:16-25

Zangrillo A, Gattinoni L. Learning from mistakes during the pandemic: the Lombardy lesson. Intensive Care Med. 2020;46:1622-1623

Drake DH, De Bonis M, Covella M, Agricola E, Zangrillo A, Zimmerman KG, Cobey FC. Echocardiography in Pandemic: Front-Line Perspective, Expanding Role of Ultrasound, and Ethics of Resource Allocation. J Am Soc Echocardiogr. 2020;33:683-689

Campochiaro C, Della-Torre E, Cavalli G, De Luca G, Ripa M, Boffini N, Tomelleri A, Baldissera E, Rovere-Querini P, Ruggeri A, Monti G, De Cobelli F, Zangrillo A, Tresoldi M, Castagna A, Dagna L; TOCI-RAF Study Group. Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study. Eur J Intern Med. 2020;76:43-49

Pisano A, Landoni G, Verniero L, Zangrillo A. Cardiothoracic Surgery at the Time of the Coronavirus Disease-2019 Pandemic: Lessons From the East (and From a Previous Epidemic) for Western Battlefields. J Cardiothorac Vasc Anesth. 2020;34:2338-2340

Renzi S, Fallanca F, Zangrillo A, Tresoldi M, Landoni G, Angelillo P, Pepe G, Pajoro U, Maestranzi G, Yacoub MR. Caring with compassion during COVID-19. Palliat Support Care. 2020;18:403-404

Gramegna M, Baldetti L, Beneduce A, Pannone L, Falasconi G, Calvo F, Pazzanese V, Sacchi S, Pagnesi M, Moroni F, Ajello S, Melisurgo G, Agricola E, Camici PG, Scandroglio AM, Landoni G, Ciceri F, Zangrillo A, Cappelletti AM. ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub. Circ Cardiovasc Interv. 2020;13:e009413

Negro A, Mucci M, Beccaria P, Borghi G, Capocasa T, Cardinali M, Pasculli N, Ranzani R, Villa G, Zangrillo A. Introducing the Video call to facilitate the communication between health care providers and families of patients in the intensive care unit during COVID-19 pandemia. Intensive Crit Care Nurs. 2020;60:102893

Monaco F, Nardelli P, Denaro G, De Luca M, Franco A, Bertoglio L, Castiglioni A, Zangrillo A. First experience with a ROTEM-enhanced transfusion algorithm in patients undergoing aortic arch replacement with frozen elephant trunk technique. A theranostic approach to patient blood management. J Clin Anesth. 2020;66:109910

Della-Torre E, Landoni G, Zangrillo A, Dagna L. Impact of sarilumab on mechanical ventilation in patients with COVID-19. Response to: 'Correspondence on: 'Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation-an open-label cohort study' by Della-Torre et al' by Cheng and Zhang. Ann Rheum Dis. 2020 Aug 19

Cavalli G, De Luca G, Campochiaro C, Della-Torre E, Ripa M, Canetti D, Oltolini C, Castiglioni B, Tassan Din C, Boffini N, Tomelleri A, Farina N, Ruggeri A, Rovere-Querini P, Di Lucca G, Martinenghi S, Scotti R, Tresoldi M, Ciceri F, Landoni G, Zangrillo A, Scarpellini P, Dagna L. Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study. Lancet Rheumatol. 2020;2:e325-e331

Ciceri F, Beretta L, Scandroglio AM, Colombo S, Landoni G, Ruggeri A, Peccatori J, D'Angelo A, De Cobelli F, Rovere-Querini P, Tresoldi M, Dagna L, Zangrillo A. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis. Crit Care Resusc. 2020;22:95-97

De Luca G, Cavalli G, Campochiaro C, Della-Torre E, Angelillo P, Tomelleri A, Boffini N, Tentori S, Mette F, Farina N, Rovere-Querini P, Ruggeri A, D'Aliberti T, Scarpellini P, Landoni G, De Cobelli F, Paolini JF, Zangrillo A, Tresoldi M, Trapnell BC, Ciceri F, Dagna L. GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study. Lancet Rheumatol. 2020;2:e465-e473

Zangrillo A, Beretta L, Silvani P, Colombo S, Scandroglio AM, Dell’Acqua A, Fominskiy E, Landoni G, Monti G, Azzolini ML, Monaco F, Oriani A, Belletti A, Sartorelli M, Pallanch O, Saleh O, Sartini C, Nardelli P, Lombardi G, Morselli F, Scquizzato T, Frontera A, Ruggeri A, Scotti R, Assanelli A, Dagna L, Rovere-Querini P, Castagna A, Scarpellini P, Di Napoli D, Ambrosio A, Ciceri F, Tresoldi M. Fast reshaping of intensive care unit facilities in a large metropolitan hospital in Milan, Italy: facing the COVID-19 pandemic emergency. Crit Care Resusc. 2020;22:91-94

Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, Cereda D, Coluccello A, Foti G, Fumagalli R, Iotti G, Latronico N, Lorini L, Merler S, Natalini G, Piatti A, Ranieri MV, Scandroglio AM, Storti E, Cecconi M, Pesenti A; COVID-19 Lombardy ICU Network. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323:1574-1581

Zangrillo A, Landoni G, Beretta L, Morselli F, Serpa Neto A, Bellomo R; COVID-BioB Study Group. Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series. Crit Care. 2020;24:227

Zangrillo A, Lomivorotov VV, Pisano A, Calabrò MG, Belletti A, Brazzi L, Grigoryev EV, Guarracino F, Monaco F, Garofalo E, Crivellari M, Likhvantsev VV, Fominskiy EV, Paternoster G, Yavorovskiy A, Pasyuga VV, Oriani A, Lembo R, Bianchi A, Scandroglio AM, Abubakirov MN, Di Tomasso N, Landoni G; CHEETAH Study Group. Long-term outcome of perioperative low cardiac output syndrome in cardiac surgery: 1-year results of a multicenter randomized trial. J Crit Care. 2020;58:89-95

Robba C, Hemmes SNT, Serpa Neto A, Bluth T, Canet J, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Putensen C, Jaber S, Schmid W, Severgnini P, Wrigge H, Battaglini D, Ball L, Gama de Abreu M, Schultz MJ, Pelosi P; FERS for the LAS VEGAS investigators; PROtective VEntilation Network and the Clinical Trial Network of the European Society of Anaesthesiology. Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study. BMC Anesthesiol. 2020;20:73

Cabrini L, Baiardo Redaelli M, Zangrillo A. "Neuromonitoring as an alternative to awake intubation in uncooperative patients at risk for cervical spine injury". Acta Anaesthesiol Scand. 2020;64:864

Drake D, Morrow CD, Kinlaw K, De Bonis M, Zangrillo A, Sade RM; Cardiothoracic Ethics Forum. Cardiothoracic Surgeons in Pandemics: Ethical Considerations. Ann Thorac Surg. 2020;110:355-358

Drake D, Morrow CD, Kinlaw K, De Bonis M, Zangrillo A, Sade RM; Cardiothoracic Ethics Forum. Cardiothoracic surgeons in pandemics: Ethical considerations. J Thorac Cardiovasc Surg. 2020;160:456-459

Sartini C, Tresoldi M, Scarpellini P, Tettamanti A, Carcò F, Landoni G, Zangrillo A. Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit. JAMA. 2020;323:2338-2340

Zangrillo A, Beretta L, Scandroglio AM, Monti G, Fominskiy E, Colombo S, Morselli F, Belletti A, Silvani P, Crivellari M, Monaco F, Azzolini ML, Reineke R, Nardelli P, Sartorelli M, Votta CD, Ruggeri A, Ciceri F, De Cobelli F, Tresoldi M, Dagna L, Rovere-Querini P, Serpa Neto A, Bellomo R, Landoni G; COVID-BioB Study Group. Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in Milan, Italy. Crit Care Resusc. 2020;22:200-211

Monti G, Cremona G, Zangrillo A, Lombardi G, Sartini C, Sartorelli M, Colombo S, Serpa Neto A, Landoni G. Home ventilators for invasive ventilation of patients with COVID-19. Crit Care Resusc. 2020;22:266-270

Pisano A, Landoni G, Zangrillo A. Protecting High-Risk Cardiac Patients During the COVID-19 Outbreak. J Cardiothorac Vasc Anesth. 2020;34:1698

Landoni G, Morselli F, Silvetti S, Frontera A, Zangrillo A. Pizza in adults and grape in children are the most frequent causes of foreign body airway obstruction in Italy. A national media-based survey. Resuscitation. 2020;149:141-142

Cabrini L, Landoni G, Zangrillo A. Minimise nosocomial spread of 2019-nCoV when treating acute respiratory failure. Lancet 2020;395:685

STARRT-AKI Investigators; Canadian Critical Care Trials Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group, the United Kingdom Critical Care Research Group, the Canadian Nephrology Trials Network, and the Irish Critical Care Trials Group, Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann M, Palevsky PM, Pettilä V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thomé F, Thorpe KE, Vaara S, Weir M, Wang AY, Young P, Zarbock A. Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020; 16;383:240-251

Cabrini L, Baiardo Redaelli M, Filippini M, Fominskiy E, Pasin L, Pintaudi M, Plumari VP, Putzu A, Votta CD, Pallanch O, Ball L, Landoni G, Pelosi P, Zangrillo A. Tracheal intubation in patients at risk for cervical spinal cord injury: A systematic review. Acta Anaesthesiol Scand. 2020;64:443-454

Monaco F, Nardelli P, Pasin L, Barucco G, Mattioli C, Di Tomasso N, Dalessandro G, Giardina G, Landoni G, Chiesa R, Zangrillo A. Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial. Br J Anaesth. 2020;124:35-43

Scquizzato T, Gazzato A, Landoni G, Zangrillo A. Assessment of noise levels in the intensive care unit using Apple Watch. Crit Care. 2020;24:130

Kim JH, Lerose CC, Landoni G, Di Prima AL, Licheri M, Oriani A, Alaidroos M, Zangrillo A, Monaco F. Differences in Biomarkers Pattern Between Severe Isolated Right and Left Ventricular Dysfunction After Cardiac Surgery. J Cardiothorac Vasc Anesth. 2020;34:650-658

Scquizzato T, Landoni G, Carenzo L, Forti A, Zangrillo A. A smartphone application with augmented reality for estimating weight in critically ill paediatric patients. Resuscitation. 2020;146:3-4

Belletti A, Nagy A, Sartorelli M, Mucchetti M, Putzu A, Sartini C, Morselli F, De Domenico P, Zangrillo A, Landoni G, Lembo R. Effect of Continuous Epinephrine Infusion on Survival in Critically Ill Patients. A Meta-Analysis of Randomized Trials. Crit Care Med. 2020;48:398-405

COVIDSurg Collaborative. Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans. Br J Surg. 2020;107:1440-1449

Pasin L, Marrocco Trischitta MM, Landoni G, Piras D, Nardelli P, Cornero G, Chiesa R,         Zangrillo A. Operative morbidity and mortality in octogenarians after carotid endarterectomy: a propensity score matching study. J Cardiovasc Surgery 2019;60:703-707

Pasin L, Nardelli P, Landoni G, Beretta L, Piras D, Baccellieri D, Chiesa R, Zangrillo A. Enhanced recovery after surgery program in elective infrarenal abdominal aortic aneurysm repair. J Cardiovasc Surg 2019;60:369-374

Cabrini L, Landoni G, Baiardo Redaelli M, Saleh O, Votta CD, Fominskiy E, Putzu A, de Souza CDS, Antonelli M, Bellomo R, Pelosi P, Zangrillo A. Correction to: Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials. Crit Care. 2019;23:325

Zangrillo A, Mazzone P, Oriani A, Pieri M, Frau G, D'Angelo G, Sartini C, Capucci R, Belletti A, Bella PD, Monaco F. Noninvasive ventilation during left atrial appendage closure under sedation: Preliminary experience with the Janus Mask. Ann Card Anaesth. 2019;22:400-406

Garofalo E, Bruni A, Pelaia C, Landoni G, Zangrillo A, Antonelli M, Conti G, Biasucci DG, Mercurio G, Cortegiani A, Giarratano A, Vetrugno L, Bove T, Forfori F, Corradi F, Vaschetto R, Cammarota G, Astuto M, Murabito P, Bellini V, Zambon M, Longhini F, Navalesi P, Bignami E. Comparisons of two diaphragm ultrasound-teaching programs: a multicenter randomized controlled educational study. Ultrasound J. 2019;11:21

Scquizzato T, Landoni G, Semeraro F, Zangrillo A. Smartphone software update could potentially affect the efficiency of lay first-responders networks in out-of-hospital cardiac arrests. Resuscitation. 2019;144:15-16

Tinelli V, Cabrini L, Fominskiy E, Franchini S, Ferrante L, Ball L, Pelosi P, Landoni G,          Zangrillo A, Secchi A. High Flow Nasal Cannula Oxygen vs. Conventional Oxygen Therapy and Noninvasive Ventilation in Emergency Department Patients: A Systematic Review and Meta-Analysis. J Emerg Med. 2019;57:322-328

Baiardo Redaelli M, Zangrillo A, Gregorc V, Ciceri F, Dagna L, Tshomba Y, Navalesi P, Landoni G. How to obtain severe hypoglycemia without causing brain or cardiac damage. Med Hypotheses. 2019;130:109276

Cabrini L, Pallanch O, Pieri M, Zangrillo A. Preoxygenation for tracheal intubation in critically ill patients: one technique does not fit all. J Thorac Dis. 2019;11:S1299-S1303

Monaco F, Barucco G, Nardelli P, Licheri M, Notte C, De Luca M, Mattioli C, Melissano G, Chiesa R, Zangrillo A. Editor’s Choice - A Rotational Thromboelastometry Driven Transfusion Strategy Reduces Allogenic Blood Transfusion During Open Thoraco-abdominal Aortic Aneurysm Repair: A Propensity Score Matched Study. Eur J Vasc Endovasc Surg. 2019;58:13-22

Shehabi Y, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Murray L, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; ANZICS Clinical Trials Group and the SPICE III Investigators. Early Sedation with Dexmedetomidine in Critically Ill Patients.          N Engl J Med. 2019;380:2506-2517

Sartini C, Lomivorotov V, Pisano A, Riha H, Baiardo Redaelli M, Lopez-Delgado JC, Pieri M, Hajjar L, Fominskiy E, Likhvantsev V, Cabrini L, Bradic N, Avancini D, Wang CY, Lembo R, Novikov M, Paternoster G, Gazivoda G, Alvaro G, Roasio A, Wang C, Severi L, Pasin L, Mura P, Musu M, Silvetti S, Votta CD, Belletti A, Corradi F, Brusasco C, Tamà S, Ruggeri L, Yong CY, Pasero D, Mancino G, Spadaro S, Conte M, Lobreglio R, Di Fraja D, Saporito E, D'Amico A, Sardo S, Ortalda A, Yavorovskiy A, Riefolo C, Monaco F, Bellomo R, Zangrillo A, Landoni G. A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality. J Cardiothorac Vasc Anesth. 2019;33:2685-2694

Bertaggia L, Baiardo Redaelli M, Lembo R, Sartini C, Cuffaro R, Corrao F, Zangrillo A,     Landoni G, Bellomo R. The Fragility Index in peri-operative randomised trials that reported significant mortality effects in adults. Anaesthesia. 2019;74:1057-1060

Monaco F, Di Tomasso N, Landoni G, Nardelli P, Radinovic A, Melillo F, D'Angelo G, Della Bella P, Zangrillo A, Mazzone P. Predictors of Intensive Care Unit Admission in Patients Undergoing Lead Extraction: A 10-Year Observational Study in a High-Volume Center. J Cardiothorac Vasc Anesth. 2019;33:1845-1851

Cabrini L, Baiardo Redaelli M, Ball L, Filippini M, Fominskiy E, Pintaudi M, Putzu A, Votta CD, Sorbello M, Antonelli M, Landoni G, Pelosi P, Zangrillo A. Awake Fiberoptic Intubation Protocols in the Operating Room for Anticipated Difficult Airway: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Anesth Analg. 2019;128:971-980

Landoni G, Lomivorotov VV, Nigro Neto C, Monaco F, Pasyuga VV, Bradic N, Lembo R, Gazivoda G, Likhvantsev VV, Lei C, Lozovskiy A, Di Tomasso N, Bukamal NAR, Silva FS, Bautin AE, Ma J, Crivellari M, Farag AMGA, Uvaliev NS, Carollo C, Pieri M, Kunstýř J, Wang CY, Belletti A, Hajjar LA, Grigoryev EV, Agrò FE, Riha H, El-Tahan MR, Scandroglio AM, Elnakera AM, Baiocchi M, Navalesi P, Shmyrev VA, Severi L, Hegazy MA, Crescenzi G, Ponomarev DN, Brazzi L, Arnoni R, Tarasov DG, Jovic M, Calabrò MG, Bove T, Bellomo R, Zangrillo A; MYRIAD Study Group. Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery. N Engl J Med. 2019;380:1214-1225

Cortegiani A, Gregoretti C, Neto AS, Hemmes SNT, Ball L, Canet J, Hiesmayr M, Hollmann MW, Mills GH, Melo MFV, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Schultz MJ, Pelosi P; LAS VEGAS Investigators, the PROVE Network, and the Clinical Trial Network of the European Society of Anaesthesiology. Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications. Br J Anaesth. 2019;122:361-369

Cabrini L, Brusasco C, Roasio A, Corradi F, Nardelli P, Filippini M, Cotticelli V, Belletti A, Ferrara L, Antonucci E, Baiardo Redaelli M, Lattuada M, Colombo S, Olper L, Ponzetta G, Ananiadou S, Monti G, Severi L, Maj G, Giardina G, Biondi-Zoccai G, Benedetto U, Gemma M, Cavallero SSM, Hajjar LA, Zangrillo A, Bellomo R, Landoni G. Non-invAsive VentIlation for early General wArd respiraTory failurE (NAVIGATE): A multicenter randomized controlled study. Protocol and statistical analysis plan. Contemp Clin Trials. 2019;78:126-132

Vetrugno L, Guadagnin GM, Barbariol F, Langiano N, Zangrillo A, Bove T. Ultrasound Imaging for Diaphragm Dysfunction: A Narrative Literature Review. J Cardiothorac Vasc Anesth. 2019;33:2525-2536

Iatrino R, Lanzani C, Bignami E, Casamassima N, Citterio L, Meroni R, Zagato L, Zangrillo A, Alfieri O, Fontana S, Macrina L, Delli Carpini S, Messaggio E, Brioni E, Dell'Antonio G, Manunta P, Hamlyn JM, Simonini M. Lanosterol Synthase Genetic Variants, Endogenous Ouabain, and Both Acute and Chronic Kidney Injury. Am J Kidney Dis. 2019;73:504-512

Ruggeri L, Franco A, Alba AC, Lembo R, Frassoni S, Scandroglio AM, Calabrò MG, Zangrillo A, Pappalardo F. Coagulation Derangements in Patients With Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation. J Cardiothorac Vasc Anesth. 2019;33:1877-1882

International Surgical Outcomes Study (ISOS) group. Prospective observational cohort study on grading the severity of postoperative complications in global surgery research. Br J Surg. 2019;106:e73-e80

Sartini C, Lomivorotov V, Pieri M, Delgado JCL, Baiardo Redaelli M, Hajjar L, Pisano A, Likhvantsev V, Fominskiy E, Bradic N, Cabrini L, Novikov M, Avancini D, Riha H, Lembo R, Gazivoda G, Paternoster G, Wang C, Tamà S, Alvaro G, Wang CY, Roasio A, Ruggeri L, Yong CY, Pasero D, Severi L, Pasin L, Mancino G, Mura P, Musu M, Spadaro S, Conte M, Lobreglio R, Silvetti S, Votta CD, Belletti A, Di Fraja D, Corradi F, Brusasco C, Saporito E, D'Amico A, Sardo S, Ortalda A, Riefolo C, Fabrizio M, Zangrillo A, Bellomo R, Landoni G. A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Reducing Mortality. J Cardiothorac Vasc Anesth. 2019;33:1430-1439

Pieri M, De Luca M, Gerli C, Crivellari M, Buzzatti N, Denti P, Stamelos M, Zangrillo A, Landoni G, Monaco F. Anesthesiologic Management of Patients Undergoing Cardiac Transapical Procedures: Which Challenges in the Modern Era? J Cardiothorac Vasc Anesth. 2019;33:1883-1889

Mamo D, Zangrillo A, Cabrini L, Leggieri C, Olper L, Monaco F, Nardelli P, Dalessandro G, Ponzetta G, Monti G, Landoni G, Greco M. Noninvasive Ventilation After Thoracoabdominal Aortic Surgery: A Pilot Randomized Controlled Trial. J Cardiothorac Vasc Anesth. 2019;33:1639-1645

Monaco F, Pieri M, Barucco G, Karprati V, Radaelli MB, De Luca M, Mattioli C, Bove T, Melissano G, Chiesa R, Landoni G, Zangrillo A. Epidural Analgesia in Open Thoraco-abdominal Aortic Aneurysm Repair. Eur J Vasc Endovasc Surg. 2019;57:360-367

Kirmeier E, Eriksson LI, Lewald H, Jonsson Fagerlund M, Hoeft A, Hollmann M, Meistelman C, Hunter JM, Ulm K, Blobner M; POPULAR Contributors. Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study. Lancet Respir Med. 2019;7:129-140

Consolo F, Sferrazza G, Motolone G, Pieri M, De Bonis M, Zangrillo A, Redaelli A, Slepian MJ, Pappalardo F. Shear-Mediated Platelet Activation Enhances Thrombotic Complications in Patients With LVAD and Is Reversed After Heart Transplantation. ASAIO J. 2019:65:e33-e35

Bignami E, Spadaro S, Saglietti F, Di Lullo A, Corte FD, Guarnieri M, de Simone G, Giambuzzi I, Zangrillo A, Volta CA. Positive end-expiratory pressure (PEEP) level to prevent expiratory flow limitation during cardiac surgery: study protocol for a randomized clinical trial (EFLcore study). Trials. 2018;19:654

Pieri M, Sorrentino T, Oppizzi M, Melisurgo G, Lembo R, Colombo A, Zangrillo A,  Pappalardo F. The role of different mechanical circulatory support devices and their timing of implantation on myocardial damage and mid-term recovery in acute myocardial infarction related cardiogenic shock. J Interv Cardiol. 2018;31:717-724

Calabrò MG, Febres D, Recca G, Lembo R, Fominskiy E, Scandroglio AM, Zangrillo A, Pappalardo F. Blood Purification With CytoSorb in Critically Ill Patients: Single-Center Preliminary Experience. Artif Organs. 2018;43:189-194

Leonardis F, De Angelis V, Frisardi F, Pietrafitta C, Riva I, Valetti TM, Broletti V, Marchesi G, Menato L, Nani R, Marson F, Fabbris M, Cabrini L, Colombo S, Zangrillo A, Coniglio C, Gordini G, Stalteri L, Giuliani G, Dalmastri V, La Manna G. Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis. Case Rep Crit Care. 2018;2018:1205613

Di Tomasso N, Carcò F, Arangino C, De Luca M, Bove T, Zangrillo A, Monaco F. Anesthetic management of carcinoid heart disease after cardiac surgery. A possible use of veno-arterial extracorporeal membrane oxygenation support. J Clin Anesth. 2018;50:91-92

Monaco F, Belletti A, Bove T, Landoni G, Zangrillo A. Extracorporeal Membrane Oxygenation: Beyond Cardiac Surgery and Intensive Care Unit: Unconventional Uses and Future Perspectives.        J Cardiothorac Vasc Anesth. 2018;32:1955-1970

Bove T, Belletti A, Putzu A, Pappacena S, Denaro G, Landoni G, Bagshaw SM, Zangrillo A. Intermittent furosemide administration in patients with or at risk for acute kidney injury: Meta-analysis of randomized trials. PLoS One. 2018;13:e0196088

Beccaria PF, Silvetti S, Lembo R, Landoni G, Monti G, Zambon M, Mamo D, Zangrillo A. The Brachiocephalic Vein as a Safe and Viable Alternative to Internal Jugular Vein for Central Venous Cannulation. Anesth Analg. 2018;127:146-150

Belletti A, Benedetto U, Putzu A, Martino EA, Biondi-Zoccai G, Angelini GD, Zangrillo A, Landoni G. Vasopressors During Cardiopulmonary Resuscitation. A Network Meta-Analysis of Randomized Trials. Crit Care Med. 2018;46:e443-e451

Zangrillo A, Alvaro G, Belletti A, Pisano A, Brazzi L, Calabrò MG, Guarracino F, Bove T, Grigoryev EV, Monaco F, Boboshko VA, Likhvantsev VV, Scandroglio AM, Paternoster G, Lembo R, Frassoni S, Comis M, Pasyuga VV, Navalesi P, Lomivorotov VV; CHEETAH Study Group. Effect of Levosimendan on Renal Outcome in Cardiac Surgery Patients With Chronic Kidney Disease and Perioperative Cardiovascular Dysfunction: A Substudy of a Multicenter Randomized Trial. J Cardiothorac Vasc Anesth. 2018;32:2152-2159

Mingxing F, Landoni G, Zangrillo A, Monaco F, Lomivorotov VV, Hui C, Novikov M, Nepomniashchikh V, Fominskiy E. Phosphocreatine in Cardiac Surgery Patients: A Meta-Analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. 2018;32:762-770

Poveda-Jaramillo R, Monaco F, Zangrillo A, Landoni G. Ultra-Short-Acting β-Blockers (Esmolol and Landiolol) in the Perioperative Period and in Critically Ill Patients. J Cardiothorac Vasc Anesth. 2018;32:1415-1425

Monaco F, Di Prima AL, De Luca M, Barucco G, Zangrillo A. Periprocedural and perioperatory management of patients with tricuspid valve disease. Minerva Cardioangiol. 2018;66:691-699

Cabrini L, Landoni G, Baiardo Radaelli M, Saleh O, Votta CD, Fominskiy E, Putzu A, Snak de Souza CD, Antonelli M, Bellomo R, Pelosi P, Zangrillo A. Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials. Crit Care. 2018;22:6

Nuzzi M, Delmonte D, Barbini B, Pasin L, Sottocorna O, Casiraghi GM, Colombo C, Landoni G, Zangrillo A. Thiopental is better than propofol for electroconvulsive therapy. Acta Biomed. 2018;88:450-456

Consolo F, Sferrazza G, Motolone G, Contri R, Valerio L, Lembo R, Pozzi L, Della Valle P, De Bonis M, Zangrillo A, Fiore GB, Redaelli A, Slepian MJ, Pappalardo F. Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device. Eur J Heart Fail. 2018;20:792-800

Pappalardo F, Ajello S, Greco M, Celińska-Spodar M, De Bonis M, Zangrillo A, Montisci A. Contemporary applications of intra-aortic balloon counterpulsation for cardiogenic shock: a "real world" experience. J Thorac Dis. 2018;10:2125-2134

Martino EA, Baiardo Redaelli M, Sardo S, Lembo R, Giordano VF, Winterton D, Ruggeri L, Hajjar LA, Zangrillo A, Landoni G. Steroids and Survival in Critically Ill Adult Patients: A Meta-analysis of 135 Randomized Trials. J Cardiothorac Vasc Anesth. 2018;32:2252-2260

Campanelli F, Landoni G, Cabrini L, Zangrillo A. Gender differences in septic intensive care unit patients. Minerva Anestesiol. 2018;84:504-508

Landoni G, Lomivorotov V, Silvetti S, Nigro Neto C, Pisano A, Alvaro G, Hajjar LA, Paternoster G, Riha H, Monaco F, Szekely A, Lembo R, Aslan NA, Affronti G, Likhvantsev V, Amarelli C, Fominskiy E, Baiardo Redaelli M, Putzu A, Baiocchi M, Ma J, Bono G, Camarda V, Covello RD, Di Tomasso N, Labonia M, Leggieri C, Lobreglio R, Monti G, Mura P, Scandroglio AM, Pasero D, Turi S, Roasio A, Votta CD, Saporito E, Riefolo C, Sartini C, Brazzi L, Bellomo R, Zangrillo A. Nonsurgical Strategies to Reduce Mortality in Patients Undergoing Cardiac Surgery: An Updated Consensus Process. J Cardiothorac Vasc Anesth. 2018;32:225-235

Scandroglio AM, Bove T, Calabrò MG, Votta CD, Pappalardo F, Giacomello R, Landoni G, Zangrillo A. Extracorporeal membrane oxygenation to resuscitate a 14-year-old boy after 43min drowning. Med Intensiva. 2018;42:509-510

Pieri M, Sardo S, Votta CD, Frau G, Oriani A, Zangrillo A, Monaco F. Improving fiberoptic intubation in the conscious patient using the new Janus mask. Med Intensiva. 2018;42:196-198

Landoni G, Lopez-Delgado JC, Sartini C, Tamà S, Zangrillo A. Halogenated agents and cardiovascular surgery: has mortality really decreased. Curr Vasc Pharmacol. 2018;16:336-343

Landoni G, Lomivorotov V, Pisano A, Neto CN, Benedetto U, Zoccai GB, Gemma M, Frassoni S, Agrò FE, Baiocchi M, Barbosa Gomes Galas FR, Bautin A, Bradic N, Carollo C, Crescenzi G, Elnakera A, El-Tahan MR, Fominskiy E, Farag AG, Gazivoda G, Gianni S, Grigoryev E, Guarracino F, Hanafi S, Huang W, Kunst G, Kunstyr J, Lei C, Lembo R, Li ZJ, Likhvantsev V, Lozovskiy A,

(Agg. mar. 2022)

Il titolare del presente curriculum vitae, pubblicato online sul portale www.unisr.it, è garante in via esclusiva della correttezza e della veridicità dei dati e delle informazioni in esso riportate e del loro eventuale e puntuale aggiornamento. Egli è dunque il diretto ed unico responsabile dei contenuti indicati nei propri curricula.