Laboratories 2022/2023 - Cellular and Molecular Biology

Please find below the list of the Supervisors (with a link to their CV) and their PhD Projects proposed for the academic year 2022/2023 for the curriculum in Cellular and Molecular Biology.

1 PROJECT-BASED FELLOWSHIP:

Project-based fellowship CMB1: FOGGETTI GIORGIA

Unit: Medical Oncology

CMB1: Unveiling novel therapeutic targets in EGFR-driven lung adenocarcinoma

BIANCHINI GIAMPAOLO

Unit: Breast Cancer Unit - Department of Medical Oncology

Novel HER2 and HER3-Targeting Antibody–Drug Conjugates (ADCs): study of antitumor efficacy and mechanism of action in in vitro models of Breast and Lung Cancer

BRAGONZI ALESSANDRA

Unit: Infection and Cystic Fibrosis

Project 1: New allelic combinations in cystic fibrosis murine models to define disease mechanisms and causes of phenotypic variation Project 2: Identifying off-targets of CFTR modulator therapy in cystic fibrosis

CARDACI SIMONE

Unit: Cancer Metabolism

Studying immunometabolic alterations in alcoholic liver disease

CAVALLI GIULIO

Age-related diseases

Dissecting and harnessing myeloid-driven inflammation in VEXAS syndrome

CENCI SIMONE

Unit: Age Related Diseases

ComBAT aging: exploring the biological bases of the exceptional longevity of bats

DE CURTIS IVAN

Unit: Cell adhesion

Kinase-controlled biomolecular condensates regulating cell migration and invasion

GABELLINI DAVIDE

Unit: Gene Expression and Muscular Dystrophy

Project 1: Structure-function characterization of a DUX4 inhibitor Project 2: Transcriptional regulation of cancer immunity

MALTECCA FRANCESCA

Unit: Mitochondrial dysfunctions in neurodegeneration

Unraveling the role of the ataxia protein sacsin in regulating Purkinje cell synapse

MAZZA DAVIDE

Unit: Imaging of Gene Regulation

Awakening the guardian of the genome: single molecule analysis of p53 action in p53-wt cancers

MILAN ENRICO

Unit: Age Related Diseases

Dissecting the molecular mechanisms regulating antibody secretion in plasma cells

MONDINO ANNA

Unit: Lymphocyte Activation

Targeting integrins by peptiCAR-T cells: a new strategy against solid tumors

MUSCO GIOVANNA

Unit: Biomolecular NMR

Project 1: Pharmacological targeting of NSD2 chromatin binding domains: a therapeutic approach against Multiple Myeloma Project 2: Structural and functional Insights into HMGB1-CXCL12-CXCR4 axis

NAI ANTONELLA

Unit: Regulation of Iron Metabolism

TFR2: A novel modulator of erythropoietin activity and cell metabolism

RAMPOLDI LUCA

Unit: Molecular Genetics of Renal Disorders

Dissecting the heterogeneous effects of renin mutations associated with Autosomal Dominant Tubulointerstitial Kidney Disease

SILVESTRI LAURA

Unit: Regulation of Iron Metabolism - Genetics and Cell Biology division

Unraveling the role of the epigenetic regulators SUV420H1-H2 in Non-Alcoholic Fatty Liver Disease and its complication

VENEREAU EMILIE

Unit: Tissue Regeneration & Homeostasis

Preclinical Evaluation of a Designer HMGB1 as a Drug Candidate for Duchenne Muscular Dystrophy

ZAMBRANO SAMUEL

Unit: Chromatin Dynamics

Spatiotemporal dynamics of NF-kappaB in liver inflammation: from single cells to tissue via 3D cultures