Neuroscience and Experimental Neurology

Laboratories 2024/2025 - Neuroscience and Experimental Neurology

Please find below the list of the Supervisors (with a link to their CV) and their PhD Projects proposed for the academic year 2024/2025 for the curriculum in Neuroscience and Experimental Neurology.

The list includes the project based fellowships and below the free projects among which the candidates, who passed the first evaluation phase, must express their preference as indicated in the Call for Applications.

4 PROJECT-BASED FELLOWSHIPS:

Project-based Fellowship NEN1: MENEGON ANDREA

Unit: CIS/Drug Screening Technologies and Alembic R&D – IRCCS Ospedale San Raffaele

Funded in the context of EU funds – NextGeneration EU- pursuant to DM 630/2024

NEN1: Acid Sensing Ion Channel isoform 3, role in glioblastoma (GBM) and as drug target for GBM treatment

Project-based Fellowship NEN2: DE GREGORIO DANILO

Unit: Neuropsychopharmacology Unit– IRCCS Ospedale San Raffaele

NEN2: Targeting the 5-HT2A receptor for treating alcohol use disorder (AUD)

Project-based Fellowship NEN3: ROCCA MARIA ASSUNTA

Unit Neuroimaging of CNS White Matter Unit, INSPE, Division of Neuroscience – IRCCS Ospedale San Raffaele

Funded in the context of EU funds – NextGeneration EU- pursuant to DM 630/2024

NEN3: Application of structural and functional MRI techniques to characterize the substrates of motor impairment and to investigate the mechanisms of different rehabilitative strategies in multiple sclerosis patients

Project-based fellowship NEN4: ALBANO LUIGI

Unit: Neurosurgery and Stereotactic Radiosurgery– IRCCS Ospedale San Raffaele

NEN4: Evaluation of spinal cord stimulation assisted by motor rehabilitation training for restoring motor function after spinal cord injury

BONANOMI DARIO

Unit: Molecular Neurobiology

Probing and targeting dysfunctional cell phenotypes in motor neuron disease

CIONI JEAN-MICHEL

Unit: RNA Biology of the Neuron

Unravelling the pathogenic processes behind Charcot-Marie-Tooth Type 2B disease.

CODAZZI FRANCA

Unit: Neuropathophysiology

Monitoring the contribution of upper motor neurons in ALS progression and propagation

COLASANTE GAIA

Unit: Stem cells and neurogenesis

Investigating the role of Scn1a in non-neuronal cell types in the brain

COLNAGHI LUCA

Unit: Protein Signalling in Brain Physiology and Pathology

Project1: Transcriptomic profiling of subjects with major depressive disorder as a new clinical tool Project2: New insights into NEDAMSS, an incurable regressive neurodevelopmental syndrome

D'ADAMO PATRIZIA

Unit: Neuroimmunology

RAB39B gene therapy and AMPAR modulation in a pre-clinical mouse model for Intellectual Disability

D'ANTONIO MAURIZIO

Unit: Biology of Myelin

Dissecting the molecular mechanisms of TDP43 cell specific toxicity in in vivo models

DE GREGORIO DANILO

Unit: Neuropsychopharmacology

The additive effect of ketamine in combination with electroconvulsive stimulation (ECS) in major depressive disorder

ESPOSITO FEDERICA

Unit: Laboratory of human genetics of neurological disorders

Evaluation of changes induced by Ocrelizumab on the T and Blymphocyte repertoire in Relapsing-Remitting multiple sclerosis patients

FARINA CINTHIA

Unit: Immunobiology of neurological disorders

Blood Transcriptomics for multiple sclerosis phenotyping

FILIPPI  MASSIMO

Unit: Neurology

Defining a multimodal machine-learning algorithm to predict disability outcomes in Frontotemporal Lobar Degeneration

GALLI ROSSELLA

Unit: Neural stem cell biology

Deconstructing the involvement of abnormally protracted corticogenesis in the etiology of cortical defects in a postnatal mouse model of Tuberous Sclerosis Complex

MALTECCA FRANCESCA

Unit: Mitochondrial dysfunctions in neurodegeneration

Developing novel therapeutic approaches for neurogenerative diseases caused by AFG3L2 mutations

MARTINO GIANVITO

Unit: Neuroimmunology

Discovery of gene regulation programs in multiple sclerosis

PANINA PAOLA

Unit: Neuroimmunology

Unveiling the role of short-chain fatty acids in neural homeostasis

POLETTI SARA

Unit: Psychiatry and Clinical Psychobiology

Profiling vulnerability and resilience for mental illness following viral infections

ROCCA MARIA ASSUNTA

Unit: Neuroimaging of CNS White Matter Unit, INSPE, Division of Neuroscience

Identifying Distinct Diagnostic and Prognostic Phenotypes in rare central nervous system disimmune disorders

SASSONE JENNY

Unit: Neuropsychopharmacology

Investigating the role od necroptosis in the axonal degeneration associated with parkinson's disease

SESSA ALESSANDRO

Unit: Neuroepigenetics

Exploring the epigenetic rewiring associated to RLF mutations as a driver of intellectual disability

SIMONATO MICHELE

Unit: Gene therapy of neurodegenerative diseases

A combinatorial gene therapy for focal epilepsy based on coordinated expression of multiple GABA-A receptor subunits

TAVEGGIA CARLA

Unit: Axo-gliali interaction

Molecular Mechanisms regulating perineural invasion in pancreatic adenocarcinoma